Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Outline of Final Research Achievements |
The study aims to develop fMRI analyses to identify disease-specific abnormal neural activity. First, we compared the spatiotemporal pattern of BOLD signal and that of the hemodynamics and showed that there might be multiple global neural activities besides local synchronous activity (i.e. so-called resting-state network: RSN) (Amemiya et al. Neuroimage 2016). In order to understand the basis of the interaction between networks, we further try to develop an analysis that enables the separate identification of both components. We have also developed a method for detecting spatiotemporal asymmetry of the spontaneous nerve activity and reported it together with the usefulness of the integrated multi-echo denoising strategy (Amemiya et al. MRM 2019).
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