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Development of MRI-compatible brachytherapy applicator for elderly asian gynecologic cancer paatients

Research Project

Project/Area Number 15K19792
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionKobe University

Principal Investigator

Uezono Haruka  神戸大学, 医学研究科, 助教 (60546480)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords子宮頸癌 / 画像誘導小線源治療 / アプリケーター / 腔内照射 / 子宮頸がん
Outline of Final Research Achievements

We conducted a study to verify the safety of the prototype applicator. On physical experiment, we confirmed the radiation effect to the surrounding tissue was equal to that of commercially available applicator. However, extremely high dose area was found to happen probably due to the short distance between each needle.
The applicator will be connected to remote after loading system (RALS) in clinical practice. Hence the connection needs to be certain so that the radioactive seed can be carried through the unit without any interruption. We have found the connection was smooth. To make it commercially available, collaboration with RALS trader is essential. We are going to build up a collaborative relationship with the company, which has not yet been carried out at the moment.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2016

All Presentation (4 results)

  • [Presentation] Change in the ADC value during the period of whole pelvic radiotherapy for cervical cancer2016

    • Author(s)
      Ryo Nishikawa
    • Organizer
      日本放射線腫瘍学会第29回学術大会
    • Place of Presentation
      京都
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] Assessment of Parametrial Response by Growth Pattern in Patients With International Federation of Gynecology and Obstetrics Stage IIB and IIIB Cervical Cancer: Analysis of Patients From a Prospective, Multicenter Trial (EMBRACE)2016

    • Author(s)
      Kenji Yoshida
    • Organizer
      ASTRO's 58th annual meeting
    • Place of Presentation
      Boston
    • Year and Date
      2016-09-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] One-year Experience of MRI Based Image Guided Adaptive Brachytherapy for Cervical Cancer2016

    • Author(s)
      Ryo Nishikawa
    • Organizer
      第75回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 当院における子宮頸部腺癌の根治的放射線治療の治療成績の検討2016

    • Author(s)
      藤本健士郎
    • Organizer
      第314回公益社団法人日本医学放射線学会関西地方会
    • Place of Presentation
      大阪
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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