| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Outline of Final Research Achievements |
I performed a prospective clinical study entitled ‘Exhaled breath condensate (EBC) collection in normal healthy volunteers’. An adequate amount of EBC was collected from all subjects. Changes in vital signs were little among the collection in all subjects. Therefore, EBC collection in my procedures seems to be feasible and safe.
Then, a prospective observational study entitled ‘Relationship between radiation pneumonitis and TGF-β1 concentration in EBC’ is under way. In an interim analysis, it seems that (1) EBC collection in my procedures may be feasible and safe in patients with lung cancer, (2) total protein and TGF-β1 concentration in EBC may increase by radiation therapy, and (3) a high value of TGF-β1 concentration in EBC may relate to occurrence of Grade 2 radiation pneumonitis.
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