Evaluation of atherosclerotic vessel wall lesions in intracranial perforating arteries using high-resolution three-dimensional magnetic resonance vessel wall imaging
| Project/Area Number |
15K19811
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 血管壁イメージング / Stroke / MRI / 血管壁イメージンング / ラクナ梗塞 / 3次元血管壁イメージング |
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| Outline of Final Research Achievements |
We evaluated atherosclerotic vessel wall lesions in intracranial arteries, including perforating arteries, among patients with acute stroke in the territory of the lenticulostriate arteries (LSA) using a high-resolution, three-dimensional (3D) T1-weighted vessel wall imaging (T1W VWI) at 7 Tesla magnetic resonance imaging (MRI) scanner. VWI showed atherosclerotic plaques in the bilateral M1 portions in all 15 patients. Although vessel wall thickening in the proximal portion of the LSA was identified in only 1 patient, high signal intensity in the distal portion of the LSA was observed in 7 patients. Use of the 3D-VWI at 7 Tesla MRI can provide direct visualization of subtle vessel wall lesions in the intracranial arteries, including perforating arteries, and can be helpful for understanding the mechanism for acute stroke.
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Report
(3 results)
Research Products
(11 results)
