Negative balanced isolated pelvic perfusion under realtime anticancer drug control

• Project/Area Number: 15K19821
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Teikyo University (2017); Nippon Medical School (2015-2016)
• Principal Investigator: Onozawa Shiro 帝京大学, 医学部, 講師 (10544398)
• Research Collaborator: MURATA Satoru 帝京大学, 医学部, 教授 ; KATADA Yoshiaki 東京女子医科大学, 医学部, 准教授
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: IVR

Outline of Final Research Achievements

The purpose of this study is to establish the rapid platinum concentration measurement in the blood. Unfortunately, we could not reach the efficient point of this study period. We had experienced the rabbit and pig model study to measure the plutonium concentration and we also had a good communication among the specialists in this field. One of the reason we could not achieve the study enough was thought that I moved the institution during the study period.

Research Products

• [Journal Article] Evaluating the Feasibility of Isolated Pancreatic Perfusion for Chemotherapy Using Computed Tomography: An Experimental Study in Pig Models (2018)
  • Author(s): Murata S, Onozawa S, Yasui D, Ueda T, Sugihara F, Shimizu A, Suzuki K, Satake M
  • Journal Title: ardiovasc Intervent Radiol. Volume: 41 Issue: 7 Pages: 1081
  • DOI: 10.1007/s00270-018-1943-y
  • Peer Reviewed
• [Journal Article] Novel treatment strategy for advanced hepatocellular carcinoma: combination of conventional transcatheter arterial chemoembolization and modified method with portal vein occlusion for cases with arterioportal shunt: a preliminary study (2018)
  • Author(s): Yasui D, Ueda T, et al.
  • Journal Title: Acta Radiologica Volume: 59 Issue: 3 Pages: 266
  • DOI: 10.1177/0284185117717762
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Endovenous Treatment for Acute Massive Pulmonary Thromboembolism (2017)
  • Author(s): Tajima H, Kaneshiro T, Takenoshita N, Ichikawa T, Isshiki S, Murata S, Onozawa S, Nakazawa K.
  • Journal Title: Annals of Vascular Diseases Volume: 10 Issue: 4 Pages: 338-344
  • DOI: 10.3400/avd.ra.17-00082
  • NAID: 130006282017
  • ISSN: 1881-641X, 1881-6428
  • Peer Reviewed / Open Access
• [Journal Article] ACTH stimulation test and computed tomography are useful for differentiating the subtype of primary aldosteronism (2017)
  • Author(s): Moriya A, Yamamoto M, Kobayashi S, Nagamine T, Takeichi-Hattori N, Nagao M, Harada T, Tanimura-Inagaki K, Onozawa S, Murata S, Tamura H, Fukuda I, Oikawa S, Sugihara H
  • Journal Title: Endocrine Journal Volume: 64 Issue: 1 Pages: 65-73
  • DOI: 10.1507/endocrj.EJ16-0297
  • NAID: 130005305972
  • ISSN: 0918-8959, 1348-4540
  • Peer Reviewed
• [Journal Article] Interventional Treatment of Severe Portal Vein Thrombosis after Living-Donor Liver Transplantation. (2016)
  • Author(s): Kawano Y, Murata S, Taniai N, Yoshioka M, Hirakata A, Mizuguchi Y, Shimizu T, Kanda T, Ueda J, Takada H, Yoshida H, Akimaru K, Onozawa S, Kumita S, Uchida E.
  • Journal Title: J Nippon Med Sch. Volume: 83 Pages: 206-210
  • NAID: 130005284975
  • Peer Reviewed / Open Access
• [Journal Article] Combination Therapy of Interventional Radiology and Surgery for Infarction of the Small Intestine Caused by Portal Vein and Mesenteric Vein Thrombosis: A Patient Report. (2016)
  • Author(s): Kimura T, Murata S, Onozawa S, Mine T, Ueda T, Sugihara F, Yasui D, Miki I, Kumita S, Ogawa T.
  • Journal Title: Yonago Acta Med. Volume: 59 Pages: 237-240
  • NAID: 120005842978
  • Peer Reviewed / Open Access
• [Journal Article] Diaphragm height varies with arm position: comparison between angiography and CT. (2016)
  • Author(s): Onozawa S, Murata S, Kimura T, Ueda T, Sugihara F, Yasui D, Tajima H.
  • Journal Title: Jpn J Radiol. Volume: 34 Pages: 724-729
  • NAID: 50010139075
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Can an enhanced thin-slice computed tomography delineate the right adrenal vein and improve the success rate? (2016)
  • Author(s): Onozawa S, Murata S, Yamaguchi H, Mine T, Yasui D, Sugihara H, Tajima H.
  • Journal Title: Jpn J Radiol Volume: 34 Pages: 611-619
  • NAID: 50010071582
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Amplatzer Vascular Plug Anchoring Technique to Stabilize the Delivery System for Microcoil Embolization (2016)
  • Author(s): Onozawa S, Murata S, Mine T, Sugihara F, Yasui D, Kumita S.
  • Journal Title: Cardiovasc Intervent Radiol Volume: 39 Issue: 5 Pages: 756
  • DOI: 10.1007/s00270-015-1248-3
  • Peer Reviewed / Open Access
• [Journal Article] Amplatzer Vascular Plug Anchoring Technique to Stabilize the Delivery System for Microcoil Embolization. (2016)
  • Author(s): Onozawa S, Murata S, Mine T, Sugihara F, Yasui D, Kumita S.
  • Journal Title: Cardiovasc Intervent Radiol Volume: 39 Pages: 756-60
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] 胸部の最新画像情報2016】 肺血栓塞栓症に対するInterventional Radiologyの実際 (2016)
  • Author(s): 田島 廣之, 金城 忠志, 竹ノ下 尚子, 市川 太郎, 一色 彩子, 中摩 健二, 佐藤 直樹, 村田 智, 小野澤 志郎, 三樹 いずみ, 山本 剛, 中沢 賢
  • Journal Title: 臨床放射線 Volume: 61 Pages: 177-184
• [Journal Article] Feasibility and Safety of Negative-Balance Isolated Pelvic Perfusion in Patients with Pretreated Recurrent or Persistent Uterine Cervical Cancer (2015)
  • Author(s): Murata S, Onozawa S, Sugihara F, Sakamoto A, Ueda T, Yamaguchi H, Yasui D, Mine T, Kumita
  • Journal Title: Annals of Surgical Oncology Volume: 22 Issue: 12 Pages: 3981
  • DOI: 10.1245/s10434-015-4494-3
  • Peer Reviewed
• [Journal Article] Minimizing systemic leakage of cisplatin during percutaneous isolated pancreas perfusion chemotherapy: A pilot study (2015)
  • Author(s): Murata Satoru, Onozawa S, Mine T, Ueda T, Sugihara F, Yasui D, Kumita S, Shimizu A, Satake M.
  • Journal Title: Radiology Volume: 276 Issue: 1 Pages: 102
  • DOI: 10.1148/radiol.15141596
  • Peer Reviewed
• [Presentation] Embolization for type 1a endoleak after TEVAR via direct transthoracic puncture in pig models (2018)
  • Author(s): S Onozawa, Y Katada, T Takano
  • Organizer: Leipzig Interventional course 2018.
  • Int'l Joint Research
• [Presentation] Massive pulmonary embolization due to embolization for renal arteriovenous fistula with huge renal vein sac (2017)
  • Author(s): Shiro Onozawa, Satoru Murata
  • Organizer: LINC 2017
  • Place of Presentation: ライプチヒ
  • Year and Date: 2017-01-24
  • Int'l Joint Research
• [Presentation] AVM直接穿刺治療におけるsyngo Dyna4Dシステムの初期臨床使用 (2017)
  • Author(s): 小野澤志郎、大内邦枝、片田芳明、高田悟朗、田島廣之、村田智、市川誠二、池野裕太
  • Organizer: 第23回血管内治療学会総会
• [Presentation] AVM直接穿刺治療におけるsyngo Dyna4Dシステムの臨床使用について (2017)
  • Author(s): 小野澤志郎、大内邦枝、片田芳明、高田悟朗、市川誠二、池野裕太
  • Organizer: 第14回日本血管腫血管奇形学会学術集会
• [Presentation] Massive pulmonary embolization due to embolization for renal arteriovenous fistula with huge renal vein sac. (2017)
  • Author(s): Shiro Onozawa, Satoru Murata
  • Organizer: Leipzig Interventional course 2017.
  • Int'l Joint Research
• [Presentation] Amplatzer Vascular Plug anchoring techniqueの有用性 (2016)
  • Author(s): 小野澤 志郎, 井上 政則, 上田 達夫, 安井 大祐, 田島 廣之, 村田 智
  • Organizer: 第５７回日本脈管学会
  • Place of Presentation: 奈良
  • Year and Date: 2016-10-13
• [Presentation] 放射線科IVR分野の卒前教育に関する実態調査2015 (2016)
  • Author(s): 西尾福 英之, 小野澤 志郎, 最上 拓児, 中島 康雄, 興梠 征典, 荒井 保明
  • Organizer: 第５２回日本医学放射線学会秋季臨床大会
  • Place of Presentation: 東京
  • Year and Date: 2016-09-16
• [Presentation] PPPD後の慢性門脈閉塞に対して再開通・ステント留置に成功した1例 (2016)
  • Author(s): 大澤 まりえ, 近藤 浩史, 棚橋 裕吉, 山本 真由, 井上 政則, 小野澤 志郎, 古井 滋
  • Organizer: 第２３回日本門脈圧亢進症学会総会
  • Place of Presentation: 神戸
  • Year and Date: 2016-09-09
• [Presentation] 下肢静脈瘤に対する血管内焼灼術 保険適用全機種の特性 (2016)
  • Author(s): 保坂 純郎, 小野澤 志郎, 大森 裕也, 山内 仁紫
  • Organizer: 第３６回日本静脈学会総会
  • Place of Presentation: 弘前
  • Year and Date: 2016-06-23
• [Presentation] 重症急性肺血栓塞栓症治療の進歩 重症急性肺血栓塞栓症に対するIVR(画像下治療)の治療成績とその評価 (2016)
  • Author(s): 田島 廣之, 金城 忠志, 竹ノ下 尚子, 三樹 いずみ, 上田 達夫, 村田 智, 小野澤 志郎, 山本 剛
  • Organizer: 第３６回日本静脈学会総会
  • Place of Presentation: 弘前
  • Year and Date: 2016-06-23
• [Presentation] 治療抵抗性および再発子宮頸癌における閉鎖循環下骨盤内灌流化学療法(NIPP)の治療成績 (2016)
  • Author(s): 杉原 史恵, 村田 智, 上田 達夫, 安井 大祐, 三樹 いずみ, 齋藤 英正, 小野澤 志郎, 坂本 篤裕, 汲田 伸一郎
  • Organizer: 第４５回日本IVR学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-05-26
• [Presentation] Liver rupture after TIPS (2016)
  • Author(s): S Onozawa, S Murata, M Shibata, et al
  • Organizer: Leipzig interventional course 2016
  • Place of Presentation: ドイツ
  • Year and Date: 2016-01-26
  • Int'l Joint Research
• [Presentation] 当院における腹部分枝debranching TEVARの治療成績 (2015)
  • Author(s): 芝田 匡史, 師田 哲郎, 栗田 二郎, 小野澤 志郎, 嶺 貴彦, 圷 宏一, 汲田 伸一郎, 清水 渉, 新田 隆
  • Organizer: 第56回脈管学会
  • Place of Presentation: 東京
  • Year and Date: 2015-10-29
• [Presentation] Technical contribution of CT during adrenal venous sampling to improve the success rate (2015)
  • Author(s): S. Onozawa, T. Ueda, F. Sugihara, D. Yasui, I. Miki, H. Sugihara, S. Murata
  • Organizer: CIRSE 2015
  • Place of Presentation: ポルトガル
  • Year and Date: 2015-09-26
  • Int'l Joint Research
• [Presentation] easibility of percutaneous isolated pancreatic perfusion chemotherapy: evaluated by CT during isolated celiac arteriography (2015)
  • Author(s): S. Murata, S. Onozawa, T. Ueda, F. Sugihara, D. Yasui, S. Kumita, K. Suzuki, M. Satake
  • Organizer: CIRSE 2015
  • Place of Presentation: ポルトガル
  • Year and Date: 2015-09-26
  • Int'l Joint Research
• [Presentation] 孤立性腹部内臓動脈解離の8例に関する臨床的特徴の検討 (2015)
  • Author(s): 圷 宏一, 山本 剛, 清水 渉, 師田 哲郎, 小野澤 志郎
  • Organizer: 日本心臓病学会学術集会
  • Place of Presentation: 横浜
  • Year and Date: 2015-09-18
• [Presentation] Interventional radiology in liver malignancies Transcatheterarterial chemoembolization for unresectable hepatocellular carcinoma with marked arterioportal shunts (2015)
  • Author(s): S Murata, S Onozawa, D Yasui , et al.
  • Organizer: IASGO 2015
  • Place of Presentation: 中国
  • Year and Date: 2015-09-04
  • Int'l Joint Research
• [Presentation] Feasibility of transcatheter arterial embolization for post-operative hemorrhage (2015)
  • Author(s): S Onozawa, S Murata, D Yasui, H Yamaguchi, et al
  • Organizer: IASGO 2015
  • Place of Presentation: 中国
  • Year and Date: 2015-09-04
  • Int'l Joint Research
• [Presentation] 2ステップ法にて腹腔内ドレナージを施行した際にガイドワイヤがアンラベルした1例 (2015)
  • Author(s): 小野澤 志郎
  • Organizer: 関東IVR研究会
  • Place of Presentation: 東京
  • Year and Date: 2015-07-12
• [Book] 塞栓物質を使いこなす (2016)
  • Author(s): 荒井 保明、中島 康雄、田島 廣之
  • Total Pages: 232
  • Publisher: メジカルビュー社
• [Funded Workshop] Leipzig Interventional Course 2017 (2017)
  • Place of Presentation: ライプチヒ、ドイツ
  • Year and Date: 2017-01-24