| Project/Area Number |
15K19859
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
NISHI Masaaki 徳島大学, 大学院医歯薬学研究部(医学系), 助教 (70464344)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 肥満 / metabolic surgery / 大腸 / 大腸バイパス / DJB / 糖尿病 / NASH / microbiome / GLUT1 / 胆汁酸 |
|---|
| Outline of Final Research Achievements |
We herein investigated the role of metabolic surgery, especially in the colon, for the morbid obesity. Metabolic surgery (Duodeno-jejunal bypass) had the effect for the nonalcoholic steatohepatitis, diabetes mellitus, and changed the gut microbiota. However, the colon bypass was not effective in our experiments
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