The relation between hepatic fiblosis and liver metastasis

Research Project

Project/Area Number	15K19910
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Digestive surgery
Research Institution	Keio University
Principal Investigator	Kondo Takayuki 慶應義塾大学, 医学部(信濃町), 助教 (40626701)
Project Period (FY)	2015-04-01 – 2017-03-31
Project Status	Completed (Fiscal Year 2016)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	肝転移 / 肝線維化 / 大腸癌 / 大腸癌肝転移
Outline of Final Research Achievements	In spleen injection, the number of liver metastasis in NASH group is higher than in normal liver group. In anti-Ki67 antibody in Immunohistochemistry, the number of stained nuclear in liver metastasis foci in NASH group was higher than in normal liver group. The ability of proliferation in Nash group was higher than in normal liver group. The ability of migration and invasion of colon cancer cell line was elevated in co-cultured with IL-13. The ability of proliferation was elevated in a concentration dependent fashion.

Report

(3 results)