| Project/Area Number |
15K19957
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Research Collaborator |
OKITA Hirokazu
NAKAJIMA Riho
INADA Yuna
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 心の理論 / 覚醒下脳手術 / トラクトグラフィ / 脳腫瘍 / 覚醒下手術 / グリオーマ / 安静時fMRI |
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| Outline of Final Research Achievements |
From the data of intraoperative mapping using theory of mind task in awake craniotomy for 15 right frontal gliomas, reproducible positive mappings could be confirmed in cortical and subcortical areas, and then overlapped on tractography and standardized brain MRI. A white matter tract "A" was a candidate tract subserving a network of mentalizing because of the three-dimensional distribution of positive mapping on the bundle in tractography and significant relationships between postoperative impairment of mentalizing and resected cavity including the white matter tract A in voxel-based lesion-symptom mapping analysis. This study suggested that structural preservation of white matte tract A would be able to maintain and improve mentalizing postoperatively in the resection of right frontal glioma.
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