Investigation on mechanisms of action of deep brain stimulation therapy for Parkinson's disease using near infrared spectroscopy
| Project/Area Number |
15K19984
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Fukuoka University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | パーキンソン病 / 脳深部刺激療法 / 脳可塑性 / 脳神経活動 / NIRS / 光イメージング / ニューロモデュレーション / 機能的神経外科 / 脳神経機能回復 |
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| Outline of Final Research Achievements |
In this study, we measured cortical activities in the brain of Parkinson's disease (PD) patients before and after deep brain stimulation (DBS) therapy using Near Infrared Spectroscopy (NIRS). Our NIRS study showed increased cortical activities as well as improvement of PD symptoms. This study sheds light on the mechanisms of DBS therapy for PD, and contributes to the development of new therapy.
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Report
(4 results)
Research Products
(22 results)
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[Presentation] Dynamic Motor-related Cortical Activity Following Deep Brain Stimulation for Parkinson's Disease: A Functional Near Infrared Spectroscopy Study2017
Author(s)
Takashi Morishita, M.D., Ph.D.,1 Masa-aki Higuchi, M.D., Ph.D.,2 Kazuya Saita, O.T.,1,3 Yoshio Tsuboi, M.D., Ph.D.,2 Hiroshi Abe, M.D., Ph.D., 1 Shogo Yamada, Hiroshi Muratani, Tooru Inoue.
Organizer
INS 13th World Congress
Related Report
Int'l Joint Research
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