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Establishment of embolic index for treatment of unruptured cerebral aneurysm by placement of endovascular device

Research Project

Project/Area Number 15K19985
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neurosurgery
Research InstitutionHirosaki University (2016)
National Cardiovascular Center Research Institute (2015)

Principal Investigator

Moriwaki Takeshi  弘前大学, 理工学研究科, 助教 (50707213)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords脳動脈瘤 / ステント / PIV / フローダイバーター / 可視化計測 / 動脈瘤
Outline of Final Research Achievements

Intracranial aneurysm (IA) flow was visualized by using in vitro flow simulator and particle image velocimetry (PIV), to propose embolic index of IA treatment. In the result, it was considered that IA with smaller dome size and wider neck width aneurysms were more difficult to embolize by stent-sheilding. It was considered that IA with sharp bend parent vessel was difficult to embolize. And, shielding performance of stent devices were compared. Shielding performance of our developed microporous covered stent was superior to bare stent and flow diverter. It is expected that this measurement method is useful to evaluate difficulty of aneurysm embolization and shielding performance of stent.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2016 2015

All Journal Article (1 results) Presentation (6 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] 脳動脈瘤塞栓治療用多孔薄膜カバードステントの開発:ワイドネック動脈瘤における塞栓可能性の検討2015

    • Author(s)
      森脇健司,日高涼,田地川勉,中山泰秀
    • Journal Title

      人工臓器

      Volume: 44巻1号 Pages: 22-22

    • Related Report
      2015 Research-status Report
  • [Presentation] 開発中の多孔薄膜カバードステントとフローダイバーターの生体外模擬循環回路を用いた動脈瘤内血流抑制能の比較2016

    • Author(s)
      森脇健司,中山泰秀,日高涼,田地川勉
    • Organizer
      第28回バイオエンジニアリング講演会
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京)
    • Year and Date
      2016-01-09
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳動脈瘤治療用多孔薄膜カバードステントの開発: フローダイバータとの瘤内血流抑制能の生体外回路での比較2016

    • Author(s)
      森脇健司,中山泰秀,日高涼,田地川勉
    • Organizer
      第39回日本バイオレオロジー学会年会
    • Place of Presentation
      東海大学校友会館
    • Related Report
      2016 Annual Research Report
  • [Presentation] In vitro hemodynamical performance comparison in endovascular devices for treating intracranial aneurysms: our microporous covered stent vs flow diverter2016

    • Author(s)
      Moririwaki Takeshi, Hidaka Ryo, Tajikawa Tsutomu, Nakayama Yasuhide
    • Organizer
      XLIII Annual Congress of the European Society for Artificial Organs
    • Place of Presentation
      Nalecz Institute of Biocybernetics and Biomedical Engineering and International Centre of Biocybernetics, Warsaw, POLAND
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] NCVCカバードステント対フローダイバーター:in vitroでの血流抑制能の比較2015

    • Author(s)
      森脇健司,日高涼,田地川勉,中山泰秀
    • Organizer
      第53回日本人工臓器学会大会
    • Place of Presentation
      東京ドームホテル(東京)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] In vitro Hemodynamical Evaluation of Microporous Covered Stents for Treatment Intracranial Aneurysms2015

    • Author(s)
      Moriwaki T, Hidaka R, Tajikawa T, Nakayama Y
    • Organizer
      XLII ANNUAL ESAO CONFERENCE
    • Place of Presentation
      KU Leuven(Belgium)
    • Year and Date
      2015-09-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 脳動脈瘤塞栓治療用多孔薄膜カバードステントの開発:外弯側動脈瘤の血流抑制能の評価2015

    • Author(s)
      森脇健司,日高涼,田地川勉,中山泰秀
    • Organizer
      第38回日本バイオレオロジー学会年会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2015-06-06
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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