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The effect of transcutaneous application of carbon dioxide on postoperative pain relief after total knee arthroplasty

Research Project

Project/Area Number 15K19997
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Orthopaedic surgery
Research InstitutionKobe University

Principal Investigator

Takayama Koji  神戸大学, 医学部附属病院, 特命助教 (80546490)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords人工膝関節置換術 / 炭酸ガス経皮吸収療法 / リハビリテーション / 炭酸ガス治療
Outline of Final Research Achievements

The purpose of this study was to examine the effects of transcutaneous CO2 application on postoperative pain relief after total knee arthroplasty (TKA). The transcutaneous CO2 application was started from the seven days after surgery and CO2 application was performed for 20 minutes for 5 days. Visual analog scale (VAS) for pain was examined before and after CO2 application. On 16 days after surgery, pain VAS, knee range of motion, and quadriceps muscle strength were compared with historical control group. The pain VAS after CO2 application was significantly decreased compared with those before application. This finding indicated that the transcutaneous CO2 application might be an alternative treatment for pain relief after TKA. On the other hand, there was no significant difference between CO2 application group and control group in pain VAS, knee range of motion, and quadriceps muscle strength on 16 days after surgery. For clinical applications, further study is required.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2018

All Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] The effect of transcutaneous application of carbon dioxide on postoperative pain relief after total knee arthroplasty2018

    • Author(s)
      Koji Takayama
    • Organizer
      Orthopaedic Research Society (ORS) 2018 Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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