Does oxytocin facilitate recovery of cesarean section-induced postoperative pain?: an examination of analgesic effects of oxytocin on postoperative pain.
| Project/Area Number |
15K20036
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology
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| Research Institution | Shinshu University |
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Principal Investigator |
Fuseya Satoshi 信州大学, 学術研究院医学系(医学部附属病院), 助教 (00588197)
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| Research Collaborator |
KAWAMATA Mikito 信州大学, 学術研究院医学系, 教授 (90315523)
KIYOSAWA Kenkichi 信州大学, 医学部附属病院, 助教 (50624772)
TANAKA Satoshi 信州大学, 学術研究院医学系, 准教授 (60293510)
MARUYAMA Yuki 信州大学, 医学部附属病院, 医員
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | オキシトシン / 術後痛 / 帝王切開 / 帝王切開術後痛 |
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| Outline of Final Research Achievements |
First, we examined whether lactation facilitated relief of cesarean section-induced postoperative pain. Second, we examined whether plasma concentrations of oxytocin were involved in relief of cesarean section-induced postoperative pain. We found that lactation facilitated relief of cesarean section-induced postoperative pain including areas of secondary hyperalgesia. However, plasma concentrations of oxytocin showed no positive correlation with areas of secondary hyperalgesia. Since these results were not consistent with the results showing that lactation facilitated relief of cesarean section-induced postoperative pain, we changed the measurement of plasma concentrations of oxytocin to measurement of saliva concentrations of oxytocin. However, we were not able to obtain stable results for measurements of oxytocin concentrations and thus the results of our study were more limited than the initial plan.
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Report
(4 results)
Research Products
(1 results)
