Involvement of CGRP and adrenomedullin in animal models of neuropathic pain
| Project/Area Number |
15K20039
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology
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| Research Institution | Shinshu University |
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Principal Investigator |
Ishida Kumiko 信州大学, 医学部, 助教(特定雇用) (80467191)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 神経因性疼痛 / CGRP / CGRPファミリー / AM |
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| Outline of Final Research Achievements |
We studied the involvement of αCGRP in neuropathic pain model by using αCGRP knockout mice and wild type mice. Our study suggested that αCGRP was not involved in spontaneous pain, thermal hyperalgesia and mechanical hyperalgesia in partial sciatic nerve ligation model.
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Report
(4 results)
Research Products
(3 results)
