New methods for diagnosis of male infertility
| Project/Area Number |
15K20086
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 男性不妊 |
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| Outline of Final Research Achievements |
We have been establishing the method to extract RNA and purify it from fertile men and infertile men. We found that Human CPβ3 (hCPβ3) that was one of the most important actin binding proteins localized in the neck legion of human sperm had an important role for male fertile. hCPβ3 is expressed in testis, changes its localization dynamically during spermatogenesis, and has some association with male infertility. We are investigating several micro RNAs that regulate this protein.
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Report
(3 results)
Research Products
(6 results)
