Analysis of cell-free mRNA in first trimester plasma from pregnant women who would develop fetal growth restriction or hepertensive disorders of pregnancy
Project/Area Number |
15K20162
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Obstetrics and gynecology
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Research Institution | Showa University |
Principal Investigator |
|
Research Collaborator |
KOIDE Keiko (90384437)
SEIKIZAWA Akihiko (10245839)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 胎児発育不全 / 胎盤機能 / 母体血中cell-free RNA / 妊娠高血圧症候群 |
Outline of Final Research Achievements |
At 8-11 weeks of gestation, cell-free HOXC4 mRNA level in plasma of pregnant women who would develop fetal growth restriction later was statistically higher than normal pregnant women. It was suggested that HOXC4 was one of the key genes in understanding pathogenesis of fetal growth restriction.
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Report
(4 results)
Research Products
(1 results)