Neural mechanisms of coordination between swallowing and respiration due to the effect of stimulation to the larynx
Project/Area Number |
15K20220
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
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Research Institution | Kyoto Prefectural University of Medicine |
Principal Investigator |
Sugiyama Yoichiro 京都府立医科大学, 医学(系)研究科(研究院), 助教 (50629566)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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Keywords | 喉頭 / 嚥下 / 電気生理学 / 喉頭科学 |
Outline of Final Research Achievements |
We first examined the contribution of the respiratory neurons in the parafacial respiratory group in the medulla, which can control the expiratory phase of breathing, to the swallowing regulation, in order to assess whether the respiratory neuronal networks could participate in the swallowing central pattern generation. In addition, we tested for effects of electrical stimulation of the neck to the swallowing reflexibility as well as respiratory rhythmogenesis. Consequently, our data suggested that the neurons of the parafacial respiratory group may contribute to the regulation of swallowing and that the surface electrical stimulation of the neck could modulate the swallowing central pattern generator in the medulla resulting in improvement of the laryngeal sensation to elicit swallowing.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Differential responses to steroid hormones in fibroblasts from the vocal fold, trachea, and esophagus.2015
Author(s)
Mukudai S, Matsuda K I, Nishio T, Sugiyama Y, Bando H, Hirota R, Sakaguchi H, Hisa Y, Kawata M
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Journal Title
Endocrinology
Volume: 156
Issue: 3
Pages: 1000-1009
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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