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Adaptive optics scanning laser ophthalmoscope for retinal vein occlusion-associated macular edema

Research Project

Project/Area Number 15K20254
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionKyoto University

Principal Investigator

Muraoka Yuki  京都大学, 医学研究科, 特定病院助教 (00739089)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords網膜循環疾患 / 黄斑浮腫 / 網膜静脈閉塞症 / 網膜循環評価 / 補償光学レーザー検眼鏡 / 赤血球凝集体速度 / AO-SLO / 凝集赤血球速度
Outline of Final Research Achievements

In the current study, I have observed affected macular lesion of eyes with retinal vein occlusion using adaptive optics scanning laser ophthalmoscopy (AO-SLO). The AO-SLO enabled quantitative measurement of the aggregated erythrocyte velocity in the parafoveal capillary network. Additionally, the aggregated erythrocyte velocity was found to strongly associate with the central foveal thickness of eyes with retinal vein occlusion. The current findings suggest that the AO-SLO evaluated erythrocyte velocity in the parafoveal capillary network would be useful for investigating for pathology of the macular edema, and prognosing for the treatment effect.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] ASSOCIATIONS BETWEEN MACULAR EDEMA AND CIRCULATORY STATUS IN EYES WITH RETINAL VEIN OCCLUSION: An Adaptive Optics Scanning Laser Ophthalmoscopy Study.2017

    • Author(s)
      Iida Y, Muraoka Y, Uji A, Ooto S, Murakami T, Suzuma K, Tsujikawa A, Arichika S, Takahashi A, Miwa Y, Yoshimura N.
    • Journal Title

      Retina

      Volume: 印刷中 Issue: 10 Pages: 1896-1904

    • DOI

      10.1097/iae.0000000000001433

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] 補償光学を用いた網膜微小循環の観察2017

    • Author(s)
      宇治彰人
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京
    • Year and Date
      2017-04-06
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 網膜静脈閉塞症の黄斑部における中心窩形態と網膜微小循環動態との関連2015

    • Author(s)
      飯田悠人、村岡勇貴、大音壮太郎、宇治彰人、高橋綾子、三輪裕子、有近重太、村上智昭、鈴間潔、辻川明孝、吉村長久
    • Organizer
      第54回日本網膜硝子体学会総会 第32回日本眼循環学会 合同学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report
  • [Presentation] Association between Foveal Pathomorphology and Microcirculatory Status in Eyes with Retinal Vein Occlusion-Associated Macular Edema2015

    • Author(s)
      Yuto Iida, Yuki Muraoka, Sotaro Ooto, Akihito Uji, Ayako Takahashi, Yuko Miwa, Shigeta Arichika, Tomoaki Murakami, Kiyoshi Suzuma, Akitaka Tsujikawa, Nagahisa Yoshimura
    • Organizer
      American Academy Ophthalmology 2015 Annual Meeting
    • Place of Presentation
      Las Vegas, United States
    • Year and Date
      2015-11-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2018-03-22  

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