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Characteristics and prevalence of uveitis in CIHHV-6 patients

Research Project

Project/Area Number 15K20293
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionNara Medical University

Principal Investigator

Yoshikawa Tadanobu  奈良県立医科大学, 医学部, 助教 (20632764)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Keywordsぶどう膜炎 / HHV6 / CIHHV6 / ヘルペスウイルス
Outline of Final Research Achievements

Multiplex PCR for herpes virus was performed in 27 eyes of 27 patients suspected herpes virus associated disease. The mean ± standard deviation age of the patients was 63.1±14.5 years. Of the 27 eyes, 12 eyes had iritis, 6 eyes had uveitis, 1 eye had endophthalmitis, 1 eye had cytomegalovirus retinopathy, 4 eyes had acute retinal necrosis, 2 eyes had secondary glaucoma, and 1 eye had herpetic keratitis. Multiplex PCR for herpes virus demonstrated that 4 eyes were cytomegalovirus positive, 2 eyes were herpes simplex virus-1 positive, 2 eyes were varicella zoster virus positive, 1 eye was Epstein-Barr virus positive, and 18 eyes were negative. None of the eyes had human herpes virus-6. Thus prevalence of uveitis with CIHHV-6 and characteristics of CIHHV-6 was unclear.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2016

All Journal Article (1 results) (of which Acknowledgement Compliant: 1 results)

  • [Journal Article] 「眼アレルギーの最新診療」に寄せる ヘルペスウイルス6型と眼疾患(2016

    • Author(s)
      吉川匡宣
    • Journal Title

      アレルギーの臨床

      Volume: 36 Pages: 776-779

    • Related Report
      2016 Annual Research Report
    • Acknowledgement Compliant

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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