| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Neuron cell is very sensitive for ischemia. After cardiac arrest and resuscitation, many neuron cells get damaged. The damage causes not only ischemia but also activation of immuno-cells, that resuts to delayed neuron death. Our hyposis was that delayed neuron damage can be suppressed by anti-activation of immuno-system. The first target was misrocria. Many reports that supressud microglia resuts to protective neurons after cardia arrest and resuscitation. But it was hard that microglia was inactivated without physical damage, and microglia inactivation did not result to neuron protect. We need to find a new target to protect neurons.
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