| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Fat fraction (FF) in the salivary glands of healthy subjects and patients with Sjogren 's syndrome was quantitatively evaluated using 6 point DIXON method which is imaging technique of MRI.
From this study, it was found that quantification of FF in salivary gland is possible by 6 point DIXON method. Furthermore, by using this technique, it was suggested that fat deposition occurs in the salivary glands depending on the physical characteristics and blood condition of the individual even in the normal group. In addition, in Sjogren 's syndrome patients, it was suggested that fatty degeneration was likely to occur in the submandibular glands. These results seemed to contribute to the establishment of new diagnostic methods and development of therapeutic methods for Sjogren 's syndrome in the future.
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