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Development of new desensitizer for hypersensitive dentin with antibacterial properties

Research Project

Project/Area Number 15K20403
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Conservative dentistry
Research InstitutionOkayama University

Principal Investigator

TAKAHASHI KEI  岡山大学, 大学病院, 助教 (00550815)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords象牙質知覚過敏抑制材 / 抗菌性 / 細菌付着性
Outline of Final Research Achievements

This study is about the adhesion of oral bacteria for the dentin which I treated in desensitizer for hypersensitive dentin. It was in the beginning representative desensitizer for hypersensitive dentin. As a result, the initial adhesion of oral bacteria tended that there was few it in comparison with the type that a hydrophilic monomer penetrated to the dentin surface, and a type to form a high polymer film on the dentin surface when I put it within this study formed a film such as hybrid layer in the adhesion.
Although antibacterial effect can be obtained constantly by adding antimicrobial ingredient to prototype desensitizer for hypersensitive dentin, its antibacterial effect did not last for a long time, addition of antimicrobial ingredient decreased physical properties and the resin bond strength to dentin.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2017 2016 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results) (of which Int'l Joint Research: 1 results) Book (1 results)

  • [Journal Article] 象牙質知覚過敏抑制材塗布がレジン接着強さに及ぼす影響2016

    • Author(s)
      高橋圭、西谷佳浩、吉山昌宏
    • Journal Title

      接着歯学

      Volume: 33 Pages: 163-169

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Mineralization of Resin Using Experimental Adhesives Containing Hydroxyapatite in Long Term2015

    • Author(s)
      Tomohiro Hoshika, Yoshihiro Nishitani, Kei Takahashi, Haruka Ogata, Naoko Ohara, Takehiro Kajihara, Masahiro Yoshiyama
    • Journal Title

      Journal of Oral Tissue Engineering

      Volume: 13(2) Pages: 85-95

    • NAID

      130005150543

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] 咬耗面積・接触面積・咬合接触点による咬耗症例の解析2016

    • Author(s)
      神農泰生、大原直子、松崎久美子、高橋圭、山路公造、吉山昌宏
    • Organizer
      第145回日本歯科保存学会学術大会
    • Place of Presentation
      キッセイ文化ホール
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] The evaluation of new all-in-one self-etching adhesives.2016

    • Author(s)
      T. Hoshika, Y. Nishitani, K. Takahashi, H. Ogata, T. Kajihara, M.
    • Organizer
      94th General Session & Exhibition of the IADR
    • Place of Presentation
      Korean
    • Year and Date
      2016-06-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 各種セルフアドヒーシブセメントのフッ素徐放性ならびに酸中和能の評価2015

    • Author(s)
      高橋圭、星加知宏、横山章人、西谷佳浩、吉山昌宏
    • Organizer
      第142回日本歯科保存学会学術大会
    • Place of Presentation
      北九州市
    • Year and Date
      2015-06-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 歯面処理方法の違いが新規ワンステップボンディング材の象牙質微小引張強さに及ぼす影響について2015

    • Author(s)
      星加知宏、西谷佳浩、高橋圭、吉山昌宏
    • Organizer
      第142回日本歯科保存学会学術大会
    • Place of Presentation
      北九州市
    • Year and Date
      2015-06-25
    • Related Report
      2015 Research-status Report
  • [Book] 第五版 保存修復212017

    • Author(s)
      田上順次、奈良陽一郎、山本一世、斉藤隆史他
    • Total Pages
      321
    • Publisher
      永末書店
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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