| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
In this study, I examined influence of the MMPs activity inhibitors on mechanical properties of the decalcified dentin and the experimental bonding system that combined the MMPs activity inhibitors with bonding resin of the self-etching system. 1). Influence on mechanical property: MMPs activity inhibitors treatment improved the mechanical property of the decalcified dentin. 2)．Influence in the dentin adhesion: In early adhesion examination, there were no decline of the bonding strength the combination to bonding agents with tannic acid until 1%. In 6 months storage, tannic acid controlled degradation of the bonding strength.
Because the change of color of the tooth substance with tannic acid and Saforide were accepted, the development of the MMPs activity inhibitors which does not cause a change of color is necessary.
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