| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
The present study aimed to develop antimicrobial photodynamic therapy (a-PDT) for dental treatment. It is well known that PDT, including a-PDT, can be used as a disinfection method. Numerous studies have demonstrated that many variables must be taken into account when developing an a-PDT protocol, including light parameters, photosensitizers and light delivery techniques. However, the mechanism of bacterial disinfection of singlet oxygen, which is the principle of PDT, has not yet been clarified. Therefore, in this study, we evaluated the relationship between bactericidal effects and sterilization mechanism by singlet oxygen using scanning electron microscopy.
In addition, further understanding of dental pulp calcification applying PDT was obtained.
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