Elucidation of the biological pathology of peri-implantitis and development of immunological therapy.
Project/Area Number |
15K20439
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Prosthodontics/ Dental materials science and
|
Research Institution | Okayama University |
Principal Investigator |
Mino Takuya 岡山大学, 医歯薬学総合研究科, 助教 (10625718)
|
Research Collaborator |
窪木 拓男 (00225195)
大野 充昭 (60613156)
大野 彩 (20584626)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 口腔インプラント / インプラント周囲炎 / 免疫応答 / 次世代シークエンサー / メタゲノム解析 |
Outline of Final Research Achievements |
It is well known that peri-implantitis is caused by bacterial infection but the constitution of bacteria causing peri-implantitis is still unclear. We did cluster analysis of NGS to investigate the bacterial flora of peri-implant exudate which was extracted from 6 patients suffering from peri-implantitis. As a result, we found five kinds of bacteria in peri-implantitis site which were not found in periodontitis teeth, and another five kinds of bacteria which were not found in normal implants.
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Report
(4 results)
Research Products
(16 results)