| Project/Area Number |
15K20449
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Nagasaki University |
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Principal Investigator |
YASUTAKE Munenori 長崎大学, 医歯薬学総合研究科(歯学系), 研究協力員 (10734163)
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| Research Collaborator |
SAWASE Takashi 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (80253681)
KUROSHIMA Shinichiro 長崎大学, 病院(歯学系), 講師 (40443915)
NAKANO Takayoshi 大阪大学, 大学院工学研究科, 教授 (30243182)
WATANABE Ikuya 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (00274671)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | デンタルインプラント / 荷重 / 骨質 / 骨細胞 / コラーゲン線維 / 生体アパタイト結晶 / 配向性 / 優先配向 / オッセオインテグレーション |
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| Outline of Final Research Achievements |
The aim of this study was to investigate the effect of neck design of dental implants on bone quality around implants under loaded conditions. Neck designs of dental implant were determined by previous reports and finite element analysis. Designed implants were placed in rabbit tibiae and received mechanical repetitive loading. Osteocyte network, and the preferential alignment of collagen fibers/biological apatite c-axis in bones around implant neck with +60 degree-grooves were significantly adapted to mechanical stimuli. Moreover, designed implants were placed in beagle mandibles and received occlusal forces via screw-retained superstructures. Occlusal forces significantly increased osseointegration and bone quality around implant neck with +60-degree-grooves.
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