Strengthening of biomedical titanium alloy for narrow implants application

• Project/Area Number: 15K20473
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Ashida Maki 東京医科歯科大学, 生体材料工学研究所, 助教 (50708386)
• Project Period (FY): 2015-04-01 – 2021-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: チタン合金 / 巨大ひずみ加工 / 金属生体材料 / 生体材料 / 材料加工・処理 / 医療・福祉 / バイオマテリアル / 機械的特性 / HPT加工

Outline of Final Research Achievements

A Ti-6Al-7Nb alloy with three different initial microstructures was processed by high-pressure torsion (HPT) and the resultant microstructure and mechanical properties of the alloy after HPT processing were investigated. The Ti-6Al-7Nb alloy with the bi-modal microstructure was strengthened more than with the equiaxed microstructure when the alloy was processed by HPT. Furthermore, the alloy with bi-modal microstructure consisting of equiaxed α-phase and acicular α’-phase showed a good balance between the tensile strength and the elongation to fracture after 1 revolution. In summary, large strength and elongation of the Ti-6Al-7Nb alloy were simultaneously achieved by HPT processing.

Academic Significance and Societal Importance of the Research Achievements

高強度チタン合金の、従来の歯科インプラントより直径の小さいナローインプラントへの応用ができれば、適用可能となる症例が増加する。これによって大がかりな骨造成手術の必要がなくなり、手術の回数、治療期間の短縮などの観点から歯科インプラント治療患者への負担を低減することができる。またナローインプラントのみではなくインプラント小型化促進につながる。

Research Products

• [Journal Article] Cytocompatibility of Ti–6Al–7Nb through High-Pressure Torsion Processing (2016)
  • Author(s): Chen P, Ashida M, Doi H, Tsutsumi Y, Horita Z, Hanawa T
  • Journal Title: MATERIALS TRANSACTIONS Volume: 57 Issue: 12 Pages: 2020-2025
  • DOI: 10.2320/matertrans.MI201515
  • NAID: 130005284477
  • ISSN: 1345-9678, 1347-5320
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] HPS加工によるTi-6Al-7Nb合金4 mm板材の高強度化 (2020)
  • Author(s): 蘆田茉希，鈴木貴大，陳 鵬，瀧沢陽一，湯本 学，小田切吉治，寺田大将，堀田善治，塙 隆夫
  • Organizer: 日本金属学会2020年秋期(第167回)講演大会
• [Presentation] Strengthening of titanium alloy by severe plastic deformation for dental narrow implants (2020)
  • Author(s): Ashida M
  • Organizer: The 7th Joint Symposium between IBB/TMDU and Chulalongkorn University
  • Int'l Joint Research / Invited
• [Presentation] 往復高圧すべり加工による生体用Ti-6Al-7Nb合金棒材の高強度化 (2020)
  • Author(s): 蘆田茉希，大塚英一，陳 鵬，瀧沢陽一，湯本 学，小田切吉治，堀田善治，塙 隆夫
  • Organizer: 日本金属学会2021年春期(第168回)講演大会
• [Presentation] Strengthening of Ti-6Al-7Nb alloy by high-pressure torsion processing (2019)
  • Author(s): Ashida M, Hanawa T, Chen P, Tsutsumi Y, Horita Z
  • Organizer: The 14th World Conference on Titanium (Ti-2019)
  • Int'l Joint Research
• [Presentation] Strengthening of Ti-6Al-7Nb alloy by high-pressure sliding (2018)
  • Author(s): Ashida M, Kitamura Y, Chen P, Doi H, Tsutsumi Y, Takizawa Y, Yumoto M, Otagiri Y, Horita Z, Hanawa T
  • Organizer: International Workshop on Giant Straining Process for Advanced Materials in 2018(GSAM2018)
  • Int'l Joint Research / Invited
• [Presentation] 高圧ねじり加工によるバイモーダル組織を有するTi-6Al-7Nb合金の高強度化 (2017)
  • Author(s): 蘆田茉希, 陳 鵬, 土居 壽, 堤 祐介, 堀田善治, 塙 隆夫
  • Organizer: 軽金属学会第133回秋期大会
• [Presentation] Strengthening of Ti-6Al-7Nb alloy with bimodal microstructure by high- pressure torsion (2017)
  • Author(s): Ashida M, Chen P, Doi H, Tsutsumi Y, Horita Z, Hanawa T
  • Organizer: International Workshop on Giant Straining Process for Advanced Materials(GSAM2017)
  • Int'l Joint Research
• [Presentation] Superplasticity of biocompatible Ti-6Al-7Nb alloy after processing by high-pressure torsion (2015)
  • Author(s): Ashida M, Chen P, Doi H, Tsutsumi Y, Hanawa T, Horita Z
  • Organizer: 12th International Conference on Superplasticity in Advanced Materials (ICSAM)
  • Place of Presentation: Tokyo(Japan)
  • Year and Date: 2015-09-08
  • Int'l Joint Research
• [Presentation] Effects of initial microstructure on the resultant microstructure and mechanical properties of Ti-6Al-7Nb alloy after HPT processing (2015)
  • Author(s): Ashida M, Chen P, Doi H, Tsutsumi Y, Hanawa T, Horita Z
  • Organizer: International workshop on giant straining process for advanced materials (GSAM2015)
  • Place of Presentation: Fukuoka(Japan)
  • Year and Date: 2015-09-03
  • Int'l Joint Research
• [Presentation] Effects of grain refinement by high-pressure torsion on mechanical properties of Ti-6Al-7Nb (2015)
  • Author(s): Ashida M, Chen P, Doi H, Tsutsumi Y, Hanawa T, Horita Z
  • Organizer: The 13th World Conference on Titanium (Ti-2015)
  • Place of Presentation: San Diego(USA)
  • Year and Date: 2015-08-16
  • Int'l Joint Research
• [Presentation] Influence of heat treatment on mechanical properties of Ti-6Al-7Nb processed by severe plastic deformation (2015)
  • Author(s): Ashida M, Chen P, Doi H, Tsutsumi Y, Hanawa T
  • Organizer: The 6th International Symposium on Advanced Materials Development and Integration of Novel Structured Metallic and Inorganic Materials (AMDI-6)
  • Place of Presentation: Tokyo(Japan)
  • Year and Date: 2015-06-09
  • Int'l Joint Research
• [Presentation] HPT加工を施したα+β型Ti-6Al-7Nb合金の組織と機械的特性 (2015)
  • Author(s): 蘆田茉希，陳 鵬，土居 壽，堤 祐介，塙 隆夫，堀田善治
  • Organizer: 軽金属学会第128回春期大会
  • Place of Presentation: 東北大学（宮城県・仙台市）
  • Year and Date: 2015-05-16