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Novel thermo-chemotherapy for oral cancer using a new magnetic anti-cancer drug

Research Project

Project/Area Number 15K20552
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionYokohama City University

Principal Investigator

SATO Itaru  横浜市立大学, 医学研究科, 客員研究員 (00737710)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords抗癌剤 / 温熱療法 / ドラッグデリバリー
Outline of Final Research Achievements

Radical surgery for patients with head and neck cancer often causes major dysfunctions, such as dysphagia, dysarthria, or mastication disorder, leading to impaired quality of life. Here, a new magnetic anticancer drug has been developed. This drug has two characteristics; anti-cancer effect and hyperthermic effect in combination with an alternating current magnetic field (ACMF). We have evaluated the anti-cancer effects of a new magnetic anticancer drug using oral cancer cells in vitro.The results in this study demonstrated the unique property of the novel magnetic anticancer compound. In particular, this drug had anti-cancer effect with heat induction in an ACMF. This drug may thus be useful in a novel cancer therapy in the future.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2015

All Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Novel thermo-chemotherapy of oral cancer using a new magnetic anti-cancer drug.2015

    • Author(s)
      Itaru Sato
    • Organizer
      The European Cancer Congress 2015.
    • Place of Presentation
      Messezentrum Vienna(オーストリア ウィーン)
    • Year and Date
      2015-09-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 口腔癌に対する新規磁性抗癌剤を用いたハイパーサーミアの開発.2015

    • Author(s)
      佐藤 格
    • Organizer
      第32回日本ハイパーサーミア学会学術大会
    • Place of Presentation
      KKRホテル大阪(大阪府大阪市)
    • Year and Date
      2015-09-04
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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