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Elucidation of the actual situation and the risk factor of the human papilloma virus infection involved in the oral cavity, pharynx cancer

Research Project

Project/Area Number 15K20644
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Social dentistry
Research InstitutionKyushu University

Principal Investigator

Takeuchi Kenji  九州大学, 歯学研究院, 助教 (10712680)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsヒトパピローマウイルス / 口腔がん / 歯学 / 唾液
Outline of Final Research Achievements

This study estimated the prevalence of high-risk human papillomavirus (HPV) infection and determined distinct risk factors for high-risk HPV infection in a community-dwelling adults aged 40-69 years. Among 574 respondents (269 men and 305 women), high-risk HPV infection was found in 25 respondents (4.4%). In a multivariate logistic regression model, higher plaque score was significantly associated with greater odds of high-risk HPV infection (plaque score >1, odds rario = 3.49, 95% confidence interval= 1.24-9.81). These findings suggest that plaque score is an important predictor of high-risk HPV infection and maintenance of oral hygiene may contribute to prevention of oral cavity, pharynx cancer in Japanese adults.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Bacterial diversity in saliva and oral health-related conditions: the Hisayama Study.2016

    • Author(s)
      Takeshita T, Kageyama S, Furuta M, Tsuboi H, Takeuchi K, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.
    • Journal Title

      Science Reorts

      Volume: 6 Issue: 1 Pages: 1-11

    • DOI

      10.1038/srep22164

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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