Circumspect Management of Oral Conditions in the Medically Compromised Patients at Perioperative Period
| Project/Area Number |
15K20655
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Social dentistry
|
|---|
| Research Institution | Tsurumi University |
|---|
Principal Investigator |
Okada Ayako 鶴見大学, 歯学部, 学部助手 (60515584)
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 易感染性宿主 / 口腔ケア / 次亜塩素酸電解水 / 細胞毒性 / 細胞間接着分子 / 感染制御 |
|---|
| Outline of Final Research Achievements |
Medically compromised patients, especially at perioperative conditions are prone to a range of oral complications majorly due to the loss of mucosal integrity. Proper preventive management would minimize the risks of oral and associated systemic complications. In recent years, electrolyzed saline solutions are gaining interests for their anti-bacterial potentials in shortest possible application time. In this study, some reactive oxygen species based electrolyzed saline solutions known as super-oxidized water (SOW) containing hypochlorous acid have been examined for their cytotoxicity. Results have indicated that a highly purified SOW containing 125 mg/L active chlorine concentrations with pH of 6.8 might be safe for useful in management of oral conditions at perioperative period especially for the medically compromised patients as it showed very low level of cytotoxicity on HeLa mucosal epithelial cells.
|
Report
(3 results)
Research Products
(26 results)
-
[Journal Article] Comparison of salivary hemoglobin measurements for periodontitis screening2017
Author(s)
Okada A, Nomura Y, Sogabe K, Oku H, Sato Gillbreath A, Hino F, Hayashi H, Yoshino H, Utsunomiya H, Suzuki K, Koresawa K, Koba K, Uetani K, Kotoh M, Nishitsuji N, Akutsu S, Nakasone T, Tobi Y, Fukuzawa Y, Yabuki Y, Naono Y, Yajima M, Shimizu K, Hanada N
-
Journal Title
Journal of Oral Science
Volume: 59
Issue: 1
Pages: 63-69
DOI
NAID
ISSN
1343-4934, 1880-4926
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
[Journal Article] Predication of the Prognosis after Initial Periodontal Treatment by Salivary Biomarkers2015
Author(s)
Ayako Okada, Yoshiaki Nomura, Kentaro Matsumoto, Kazuaki Yamane, Tatsuhiko Yoshida, Megumi Hatano, Shinya Miyamatsu, Naomi Fukaishi, Tomoya Amagasaki, Kumiko Nagamatsu, Hiroo Yoshikawa, Takahide Gunji , Seiji Kajiura and Nobuhiro Hanada
-
Journal Title
Asian Pacific Journal of Dentistry
Volume: 15
Pages: 25-31
NAID
Related Report
Peer Reviewed / Open Access
-
[Journal Article] Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease2015
Author(s)
Terai T, Okumura T, Imai S, Nakao M, Yamaji K, Ito M, Nagata T, Kaneko K, Miyazaki K, Okada A, Nomura Y, Hanada N
-
Journal Title
PLoS One
Volume: 10
Issue: 6
Pages: 1-20
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Trial of a Liquid Carrier Type Dental Drug Delivery Tray2015
Author(s)
Ayako Okada, Takatoshi Murata, Khairul Matin, Mayu Miyanohara, Kaoru Sogabe, Ryoko Otsuka, Masaru Kirihara, Masazumi Matsuzawa, Tomomi Sudo, Susumu Imai, Junji Tagami, Nobuhiro Hanada
Organizer
the 63rd Annual meeting of JADR
Place of Presentation
FUKUOKA INTERNATIONAL CONGRESS CENTER (Fukuoka Japan)
Year and Date
2015-10-30
Related Report
Int'l Joint Research
-
-
-
-
-
-
-
[Book] 歯科発アクティブライフプロモ－ション21 健康増進からフレイル予防まで2017
Author(s)
武内博朗, 泉福英信, 野村義明, 花田信弘, 村田貴俊, 山田秀則, 岡田彩子, 宮之原真由, 有吉芽生, 曽我部薫, 浦口昌秀
Total Pages
119
Publisher
デンタルダイヤモンド社
Related Report
