The new evaluation method for cardiopulmonary cerebral resuscitation by using Near-Infrared Spectroscopy - easily, non-invasively, and real-timely -
| Project/Area Number |
15K20883
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Emergency medicine
Brain biometrics
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 脳組織酸素飽和度 / 心拍再開 / 心肺脳蘇生 / 近赤外線分光法 / 心原性心停止 / 呼吸原性心停止 |
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| Outline of Final Research Achievements |
The present study demonstrated that the validity of cerebral tissue oxygen saturation (Tissue oxygen Index: TOI) of NIRO-Pulse compared with near-infrared spectroscopy in porcine cerebral blood flow and clinical data.
In a porcine model, TOI value was strongly correlated with cerebral tissue oxygen partial pressure. In the cases of cardiogenic cardiac arrest (CA) and respiratory CA, respectively, the TOI showed the lowest value in 4 minutes after oxygen. In the cases of cardiogenic CA, the TOI value immediately normalized. Return of spontaneous circulation (ROSC) could be obtained if the TOI is maintained or increased again after decreased on normal value. In respiratory CA, ROSC could be obtained if the TOI level is continuously increased.
On the other hand, in the clinical data, about 60% of TOI implied the area dominated by the internal carotid artery. TOI is observed the brain more. ROSC was obtained if the TOI value is high on arrival at hospital and continuously increased.
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Report
(3 results)
Research Products
(10 results)
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[Presentation] 2)初期波形 Asytole で１時間以上心肺蘇生を行い良好な脳組織酸素飽和度を呈し社会復帰した１例.2015
Author(s)
久後舟平,小山泰明,丸島愛樹,山崎裕一朗,萩谷圭一,榎本有希,宮顕,塩入瑛里子,秋山大樹,下條信威,河野了,水谷太郎.
Organizer
第43回日本救急医学会総会
Place of Presentation
東京国際フォーラム（東京都千代田区）
Year and Date
2015-10-21
Related Report
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