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High-speed optical imaging engine for multifunctional investigation of the ey

Research Project

Project/Area Number 15K20887
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Optical engineering, Photon science
Biomedical engineering/Biomaterial science and engineering
Research InstitutionUniversity of Tsukuba

Principal Investigator

Hong Young-Joo  筑波大学, 医学医療系, 助教 (40738431)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsOCT / motion correction / Lissajous scan / optical buffering / PMD / envelope modulation
Outline of Final Research Achievements

I had replaced the research approach to meet the fundamental goal of high speed optical coherence tomography(OCT) engine which aiming reduction of motion artifacts. The another approach is the correction of motion artifacts by using particularly designed scanning protocol.
A Lissajous scanning pattern, which has a trajectory that frequently overlaps with itself, was adopted and designed for OCT volume scan, and a three-dimensional eye motion correction method was developed. Eye motion artifacts were corrected automatically by software. By comparing the image without and with the motion correction, it was shown the effectiveness of the method. An experiment was performed and the results corrected by our method was compared with the ground truths to verify its validity. The experimental results showed that our method effectively corrects eye motion artifacts. Furthermore, the sufficient repeatability of our method was confirmed.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (8 results)

All 2017 2016 2015

All Journal Article (5 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 5 results,  Open Access: 4 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Three-dimensional eye motion correction by Lissajous scan optical coherence tomography2017

    • Author(s)
      Yiwei Chen, Young-Joo Hong, Shuichi Makita, and Yoshiaki Yasuno
    • Journal Title

      Biomedical Optics Express

      Volume: 8 Issue: 3 Pages: 1783-1802

    • DOI

      10.1364/boe.8.001783

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Eye motion corrected OCT imaging with Lissajous scan pattern2016

    • Author(s)
      Young-Joo Hong, Yiwei Chen, En Li, Masahiro Miura, Shuichi Makita, and Yoshiaki Yasuno
    • Journal Title

      SPIE Proceedings

      Volume: 9693 Pages: 96930P-96930P

    • DOI

      10.1117/12.2212227

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Noise-immune complex correlation for optical coherence angiography based on standard and Jones matrix optical coherence tomography2016

    • Author(s)
      S Makita, K Kurokawa, YJ Hong, M Miura, Y Yasuno
    • Journal Title

      Biomed. Opt. Express

      Volume: 7 Issue: 4 Pages: 1525-1548

    • DOI

      10.1364/boe.7.001525

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography2015

    • Author(s)
      S Sugiyama, YJ Hong, D Kasaragod, S Makita, S Uematsu, Y Ikuno, M Miura , Y Yasuno
    • Journal Title

      Biomed. Opt. Express

      Volume: 6 Issue: 12 Pages: 4951-4974

    • DOI

      10.1364/boe.6.004951

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] In-plane and out-of-plane tissue micro-displacement measurement by correlation coefficients of optical coherence tomography2015

    • Author(s)
      Kazuhiro Kurokawa, Shuichi Makita, Young-Joo Hong, Yoshiaki Yasuno
    • Journal Title

      Optics Letters

      Volume: 40 Issue: 9 Pages: 2153-2156

    • DOI

      10.1364/ol.40.002153

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Eye motion corrected OCT imaging with Lissajous scan pattern2016

    • Author(s)
      Young-Joo Hong, Yiwei Chen, En Li, Masahiro Miura, Shuichi Makita, Yoshiaki Yasuno
    • Organizer
      Photonics West, BiOS
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-02-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Lissajous scan applied eye motion correction for OCT volume imaging2015

    • Author(s)
      Young-Joo Hong,, Shuichi Makita, Masahiro Miura,, Yoshiaki Yasuno
    • Organizer
      Optics and Photonics Japan
    • Place of Presentation
      Tokyo,Japan
    • Year and Date
      2015-10-29
    • Related Report
      2015 Research-status Report
  • [Presentation] Multifunctional OCT imaging of macular degeneration for vasculature, RPE and choroid investigation2015

    • Author(s)
      Young-Joo Hong, Masahiro Miura, Shuichi Makita, Deepa Kasaragod, Satoshi Sugiyama, Yoshiaki Yasuno
    • Organizer
      The Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Denver, USA
    • Year and Date
      2015-05-06
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2018-03-22  

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