| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
Plants have typical sphingolipid structures distinct from other eukaryotes. To dissect plant-specific structures of sphingolipids, we established a comprehensively targeted sphingolipidomics technology based on theoretical library covering whole molecular species present in plants. The technical development provided new insights into molecular functions of plant-specific sphingolipid structures in the formation of functional lipid-protein clusters as plasma membrane microdomains. Moreover, we succeeded to identify a novel glycosyl transferase gene family responsible for biosynthesis of the diverse sugar chains of plant sphingolipids. These results will further accelerate understanding of molecular functions of plant sphingolipids as well as applied biotechnological development through metabolic engineering of sphingolipids.
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