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Development of 3D-Magnetic Tweezer System for Live Cell Experiment

Research Project

Project/Area Number 15K20994
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Biomedical engineering/Biomaterial science and engineering
Research InstitutionTokyo Institute of Technology

Principal Investigator

Matsuura Daisuke  東京工業大学, 工学院, 助教 (40618740)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords非接触マニピュレーション / 磁気駆動 / 精密画像計測 / 設計工学 / バイオロボティクス / 精密工学 / 磁気テザー / 精密マニピュレーション
Outline of Final Research Achievements

This research is aiming to figure out a systematic design procedure of sextuple 3D-magnetic tweezer that is utilizing magnetic levitation technique to achieve a non-contact magnetic force exertion to a micro-sized magnetic particle, which is effective for establishing a position control of a free-floating particle in medium or a measurement of mechanical property, such as stiffness, of a specimen cell on which the particle is attached. In order to satisfy a given specification which includes a strength, frequency and a size of workspace in which anisotropy of the generative force can be within a permissible value, a practical procedure to find a combination of proper material, tip shape and number of turns of excitation coils was determined. By using this procedure, a setup has been fabricated, and a semi-closed loop magnetic force control using a Hall element sensor mounted on each pole’s end side was applied. Obtained performance of the developed system was experimentally evaluated.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2016 2015

All Presentation (4 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] 生細胞試験用3次元磁気テザーの設計・試作と発生力制御2017

    • Author(s)
      松浦大輔,青木仁志,菅原雄介,武田行生
    • Organizer
      日本機械学会ロボティクス・メカトロニクス講演会2017
    • Place of Presentation
      福島県郡山市
    • Year and Date
      2017-05-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] Development of a 3D-Magnetic Tweezer System Having Magnetic Pole Positioning Mechanism2016

    • Author(s)
      Daisuke Matsuura, Hitoshi Aoki and Yukio Takeda
    • Organizer
      IEEE International Conference on Robotics and Automation (ICRA2016)
    • Place of Presentation
      スウェーデン,ストックホルム市
    • Year and Date
      2016-05-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 3D-Magnetic Tweezer for Live Cell Experiment2016

    • Author(s)
      Daisuke Matsuura, Yukio Takeda.
    • Organizer
      Proc. of the First International Engineering Forum 2016
    • Place of Presentation
      台湾科学技術大学
    • Year and Date
      2016-02-21
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 磁極位置決め機構を有する3次元磁気テザーシステムの設計・試作と発生力の測定2015

    • Author(s)
      青木仁志, 松浦大輔, 武田行生
    • Organizer
      第21回日本IFToMM会議シンポジウム前刷集
    • Place of Presentation
      東京工業大学
    • Year and Date
      2015-07-18
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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