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Three-dimensional printer-generated patient-specific phantom for artificial in-vivo dosimetry in radiotherapy quality assurance

Research Project

Project/Area Number 15K21060
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Radiation science
Research InstitutionNagoya University

Principal Investigator

KAMOMAE Takeshi  名古屋大学, 医学部附属病院, 病院助教 (60706282)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords放射線治療 / 品質管理 / 3Dプリンタ / 三次元積層造形 / 個別化医療 / 三次元造形 / 患者個別 / 線量計測 / 医学物理学 / 患者模擬ファントム / 3次元造形
Outline of Final Research Achievements

Pretreatment patient-specific quality assurance for radiotherapy is performed by measurement using simple rectangular or cylindrical phantoms; thus, the dosimetric errors caused by complex patient-specific anatomy are absent in the evaluation objects. In this study, we constructed a system for generating patient-specific three-dimensional (3D)-printed phantoms based on the patient computed tomography data sets. The results of this study demonstrated the feasibility of the 3D-printed phantom for artificial in-vivo dosimetry in radiotherapy quality assurance. This developed method will be the remarkable progress of the advanced dosimetry in radiotherapy and contribute to establishment and promotion of the precision and personalized radiotherapy treatment.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (35 results)

All 2017 2016 2015 Other

All Journal Article (10 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 10 results,  Open Access: 6 results,  Acknowledgement Compliant: 1 results) Presentation (24 results) (of which Int'l Joint Research: 9 results,  Invited: 1 results) Remarks (1 results)

  • [Journal Article] A novel radiation protection device based on tungsten functional paper for application in interventional radiology.2017

    • Author(s)
      Monzen H, Tamura M, Shimomura K, Onishi Y, Nakayama S, Fujimoto T, Matsumoto K, Hanaoka K, Kamomae T.
    • Journal Title

      J Appl Clin Med Phys.

      Volume: 18(3) Issue: 3 Pages: 215-220

    • DOI

      10.1002/acm2.12083

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of multi-leaf collimator leaf transmission on head and neck intensity-modulated radiation therapy and volumetric-modulated arc therapy planning2017

    • Author(s)
      Sasaki Motoharu、Tominaga Masahide、Kamomae Takeshi、Ikushima Hitoshi、Kitaoka Motonori、Bando Ryota、Sakuragawa Kanako、Oita Masataka
    • Journal Title

      Japanese Journal of Radiology

      Volume: 35 Issue: 9 Pages: 511-525

    • DOI

      10.1007/s11604-017-0661-8

    • NAID

      50012661035

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical usefulness of MLCs in robotic radiosurgery systems for prostate SBRT2017

    • Author(s)
      Tomida Masashi、Kamomae Takeshi、Suzuki Junji、Ohashi Yoichi、Itoh Yoshiyuki、Oguchi Hiroshi、Okuda Takahito
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: 18 Issue: 5 Pages: 124-133

    • DOI

      10.1002/acm2.12128

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three-dimensional printer-generated patient-specific phantom for artificial in vivo dosimetry in radiotherapy quality assurance2017

    • Author(s)
      Kamomae Takeshi、Shimizu Hidetoshi、Nakaya Takayoshi、Okudaira Kuniyasu、Aoyama Takahiro、Oguchi Hiroshi、Komori Masataka、Kawamura Mariko、Ohtakara Kazuhiro、Monzen Hajime、Itoh Yoshiyuki、Naganawa Shinji
    • Journal Title

      Physica Medica

      Volume: 44 Pages: 205-211

    • DOI

      10.1016/j.ejmp.2017.10.005

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dosimetric feasibility of using tungsten-based functional paper for flexible chest wall protectors in intraoperative electron radiotherapy for breast cancer2017

    • Author(s)
      Kamomae Takeshi、Monzen Hajime、Kawamura Mariko、Okudaira Kuniyasu、Nakaya Takayoshi、Mukoyama Takashi、Miyake Yoshikazu、Ishihara Yoshitomo、Itoh Yoshiyuki、Naganawa Shinji
    • Journal Title

      Phys Med Biol.

      Volume: 63 Issue: 1 Pages: 015006-015006

    • DOI

      10.1088/1361-6560/aa96cf

    • NAID

      120006473526

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of stochastic noise and post-irradiation density growth for reflective-type radiochromic film in therapeutic photon beam dosimetry.2016

    • Author(s)
      Takeshi Kamomae, Masataka Oita, Naoki Hayashi, Motoharu Sasaki, Hideki Aoyama, Hiroshi Oguchi, Mariko Kawamura, Hajime Monzen, Yoshiyuki Itoh, Shiniji Naganawa
    • Journal Title

      Phys Med.

      Volume: 32 Issue: 10 Pages: 1314-1320

    • DOI

      10.1016/j.ejmp.2016.07.091

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Late Rectal Toxicity from Image-guided Intensity Modulated Radiotherapy for Prostate Cancer2016

    • Author(s)
      Sayo Maki, Yoshiyuki Itoh, Seiji Kubota, Tohru Okada, Rie Nakahara, Junji Ito, Mariko Kawamura, Takeshi Kamomae, Shinji Naganawa, Yasushi Yoshio, Momokazu Gotoh, Mitsuru Ikeda
    • Journal Title

      Anticancer Research

      Volume: 36 (6) Pages: 2967-2973

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationship between prostate volume changes and treatment duration of neoadjuvant androgen deprivation during intensity-modulated radiation therapy for Japanese patients with prostate cancer2016

    • Author(s)
      Masashi Tomida, Kuniyasu Okudaira, Takeshi Kamomae, Hiroshi Oguchi, Yoshikazu Miyake, Kazuo Yoneda, Yoshiyuki Itoh
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 78 (3) Pages: 313-321

    • NAID

      120005837933

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dosimetric impact of dental metallic crown on intensity-modulated radiotherapy and volumetric-modulated arc therapy for head and neck cancer2016

    • Author(s)
      Takeshi Kamomae, Yoshiyuki Itoh, Kuniyasu Okudaira, Takayoshi Nakaya, Masashi Tomida, Yoshikazu Miyake, Hiroshi Oguchi, Takehiro Shiinoki, Mariko Kawamura, Noriyuki Yamamoto, Shinji Naganawa
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: 17 Issue: 1 Pages: 234-245

    • DOI

      10.1120/jacmp.v17i1.5870

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Comparison of Dose Accuracy between Film and Two-dimensional Detectors in Intensity-modulated Radiation Therapy2015

    • Author(s)
      Yuichi Onishi, Shinichi Nakayama, Shinsaku Watanabe, Souichirou Kaneshige, Hajime Monzen, Kenji Matsumoto, Naoya Shintani, Takeshi Kamomae
    • Journal Title

      Journal of the Korean Physical Society

      Volume: 67 Issue: 1 Pages: 89-95

    • DOI

      10.3938/jkps.67.89

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] A new shield for intra operative electron radiotherapy (IOERT) of early breast cancer2017

    • Author(s)
      Mariko Kawamura, Takeshi Kamomae, Yoshiyuki Itoh, Tohru Okada, Seiji Kubota, Kana Kimura, Yuka Kozai, Yumi Oie, Yuki Takase, Shinji Naganawa
    • Organizer
      The 2nd Meeting of Federation of Asisan Organizations for Radiation Oncology (FARO)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] MRI-visible phantom fabricated using material jetting three-dimensional printing with nanocomposite hydrogel for MRI-guided therapy simulation2017

    • Author(s)
      Takeshi Kamomae, Tomohiro Komada, Yutaka Kato, Kuniyasu Okudaira, Takashi Matsumura, Yoshihiro Norikane, Tatsuya Niimi, Yoshiyuki Itoh, Shinji Naganawa
    • Organizer
      8th Japan-Korea Joint Meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characterization of stochastic noise and post-irradiation density growth for GAFCHROMIC EBT-XD films in therapeutic photon beam dosimetry2017

    • Author(s)
      Yuichi Onishi, Hajime Monzen, Takeshi Kamomae, Shinichi Nakayama, Yutako Oyama, Hirofumi Enomoto, Miharu Oshima, Ayako Mori
    • Organizer
      8th Japan-Korea Joint Meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 3Dプリンタの医用応用と放射線治療品質管理への利用に向けて2017

    • Author(s)
      加茂前 健
    • Organizer
      東海放射線腫瘍研究会第45回技術部会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] An attempt to create a blood vessel model by 3D printer using a hydrogel2017

    • Author(s)
      Tomohiro Komada, Takeshi Kamomae, Jun Ito, Hiroyasu Umakoshi, Ken Nagasaka, Masaya Matsushima, Kojiro Suzuki, Makoto Tsuduki, Takeshi Uemura, Takashi Matsumura, Yoshihiro Norikane, Tatsuya Niimi, Shinji Naganawa
    • Organizer
      第46回日本IVR学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] A sensitivity calibration of radiophotoluminescent glass dosimeter for scattered therapeutic x-ray in water equivalent phantom2017

    • Author(s)
      Shouichi Yokose, Masataka Komori, Takeshi Kamomae, Hidetoshi. Shimizu, Kuniyasu Okudaira, Fumiaki Kawabata, Hiroshi Oguchi
    • Organizer
      第113回日本医学物理学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 放射線治療分野における3Dプリンタの活用2017

    • Author(s)
      加茂前 健
    • Organizer
      平成28年度東北大学医学物理セミナー
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a patient-specific QA system by three-dimensional printing technique2016

    • Author(s)
      Takeshi Kamomae, Hidetoshi Shimizu, Takayoshi Nakaya, Takashi Mukouyama, Kuniyasu Okudaira, Yoshikazu Miyake, Masataka Komori, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
    • Organizer
      22nd International Conference on Medical Physics
    • Place of Presentation
      Bangkok (Thailand)
    • Year and Date
      2016-12-09
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] CLINICAL ADVANTAGES OF A ROBOTIC RADIOSURGERY SYSTEM EQUIPPED WITH A MULTI-LEAF COLLIMATOR IN PROSTATE STEREOTACTIC BODY RADIATION THERAPY2016

    • Author(s)
      Masashi Tomida, Junji Suzuki, Hironori Takahashi, Kyohei Hamajima, Takeshi Kamomae, Yoichi Ohashi, Hiroshi Oguchi, Takahito Okuda
    • Organizer
      22nd International Conference on Medical Physics
    • Place of Presentation
      Bangkok (Thailand)
    • Year and Date
      2016-12-09
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] MAGICゲル線量計の容器サイズに起因する感度変化の補正2016

    • Author(s)
      小島優芽, 田淵麻香, 小口 宏, 奥平訓康, 加茂前健, 櫻井康雄, 小森雅孝
    • Organizer
      第5回3次元ゲル線量計研究会
    • Place of Presentation
      京都大学宇治キャンパス(京都府宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 名古屋大学におけるMAGICゲル線量計のR2値の変動2016

    • Author(s)
      田中沙弥, 小島優芽, 田淵麻香, 小口 宏, 奥平訓康, 櫻井康雄, 加茂前健, 小森雅孝
    • Organizer
      第5回 3次元ゲル線量計研究会
    • Place of Presentation
      京都大学宇治キャンパス(京都府宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 甲状腺機能亢進症の131I内用療法における吸収線量測定の基礎的検討2016

    • Author(s)
      柳 秀輝, 阿部真治, 藤田尚利, 櫻木庸博, 加茂前健, 清水秀年, 小森雅孝, 小芝有美子, 本田将之, 国本啓太, 加藤克彦
    • Organizer
      第36回日本核医学技術学会総会学術大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2016-11-03
    • Related Report
      2016 Research-status Report
  • [Presentation] Development of a patient-specific QA system by three-dimensional printing technique2016

    • Author(s)
      Takeshi Kamomae, Hidetoshi Shimizu, Takayoshi Nakaya, Takashi Mukouyama, Kuniyasu Okudaira, Yoshikazu Miyake, Masataka Komori, Hiroshi Oguchi, Yoshiyuki Itoh, Shinji Naganawa
    • Organizer
      第112回日本医学物理学会学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-10-08
    • Related Report
      2016 Research-status Report
  • [Presentation] Dose Impact of Rectal Gas on Prostate VMAT2016

    • Author(s)
      Motoharu Sasaki, Hitoshi Ikushima, Masahide Tominaga, Tetsuya Kawashita, Takeshi Kamomae, Ryota Bando, Kanako Sakuragawa, Masataka Oita.
    • Organizer
      2016 AAPM Annual Meeting
    • Place of Presentation
      Washington, D.C. (USA)
    • Year and Date
      2016-07-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The influence of container size on polymer gel dosimetry2016

    • Author(s)
      Yume Kojima, Takayuki Miyachi, Hiroshi Oguchi, Kuniyasu Okudaira, Takeshi Kamomae, Yasuo Sakurai, Masataka Komori
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2016 Research-status Report
  • [Presentation] PHITSを用いた放射線治療用電子線に対する金属粉含有機能紙の遮蔽性能評価2016

    • Author(s)
      加茂前健, 門前一, 川村麻里子, 奥平訓康, 中谷隆佳, 向山隆史, 末澤正太郎, 川端文隆, 杉田和真, 三宅良和, 小口宏, 伊藤善之, 長縄慎二
    • Organizer
      PHITS研究会
    • Place of Presentation
      TKP熱海研修センター(静岡県熱海市)
    • Related Report
      2016 Research-status Report
  • [Presentation] CTによるポリマーゲル線量計の信号取得2015

    • Author(s)
      宮地貴之, 小島優芽, 小口宏, 奥平訓康, 堤貴紀, 加茂前健, 小森雅孝
    • Organizer
      第4回3Dゲル線量計研究会
    • Place of Presentation
      帝京大学(東京都板橋区)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
  • [Presentation] MAGICゲル線量計の有用性の総合評価2015

    • Author(s)
      田中文野, 宮地貴之, 小島優芽, 小口宏, 奥平訓康, 櫻井康雄, 加茂前健, 小森雅孝
    • Organizer
      第4回3Dゲル線量計研究会
    • Place of Presentation
      帝京大学(東京都板橋区)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
  • [Presentation] カラギーナンを用いたMAG系ゲル線量計の基礎的検討2015

    • Author(s)
      田淵麻香, 宮地貴之, 小島優芽, 小口宏, 奥平訓康, 櫻井康雄, 加茂前健, 小森雅孝
    • Organizer
      第4回3Dゲル線量計研究会
    • Place of Presentation
      帝京大学(東京都板橋区)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
  • [Presentation] ポリマーゲル線量計での算出線量に対する容器サイズの影響2015

    • Author(s)
      小島優芽, 宮地貴之, 小口 宏, 奥平訓康, 加茂前健, 櫻井康雄, 小森雅孝
    • Organizer
      第4回3Dゲル線量計研究会
    • Place of Presentation
      帝京大学(東京都板橋区)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
  • [Presentation] Characterization of Stochastic Noise and Post-Exposure Density Growth for Reflective-Type Radiochromic Film in Therapeutic Photon Beam Dosimetry2015

    • Author(s)
      Takeshi Kamomae, Masataka Oita, Naoki Hayashi, Motoharu Sasaki, Hideki Aoyama, Yoshiyuki Itoh, and Shinji Naganawa
    • Organizer
      15th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      西安(中華人民共和国)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Double-energy CT scanによる陽子線阻止能比の算出2015

    • Author(s)
      下小牧遼太, 小森雅孝, 大町千尋, 柴田洋希, 歳藤利行, 加茂前健, 小口宏
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Dual energy CTを利用したポリマーゲル線量計の信号取得の評価2015

    • Author(s)
      宮地貴之, 小島優芽, 小口宏, 奥平訓康, 加茂前健, 堤貴紀, 小森雅孝
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Evaluation of Tungsten-Based Functional Paper for Attenuation Device in Intraoperative Radiotherapy for Breast Cancer2015

    • Author(s)
      Takeshi Kamomae, Hajime Monzen, Kuniyasu Okudaira, Yoshikazu Miyake, Hiroshi Oguchi, Masataka Komori, Mariko Kawamura, Yoshiyuki Itoh, Toyone Kikumori, Shinji Naganawa
    • Organizer
      2015 AAPM Annual Meeting
    • Place of Presentation
      Anaheim(アメリカ合衆国)
    • Year and Date
      2015-07-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 名古屋大学学術機関リポジトリ

    • URL

      http://hdl.handle.net/2237/27925

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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