Lipid-bilayer-assisted self-assembly of DNA origami arrays and their functionalization
| Project/Area Number |
15K21093
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanobioscience
Nanostructural chemistry
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| Research Institution | Tohoku University (2016)
Kyoto University (2015) |
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Principal Investigator |
Suzuki Yuki 東北大学, 学際科学フロンティア研究所, 助教 (50636066)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | DNAナノテクノロジー / DNAオリガミ / 脂質二分子膜 / 自己集合化 / 自己組織化 / ボトムアップ技術 / 原子間力顕微鏡 / 人工脂質二分子膜 |
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| Outline of Final Research Achievements |
In this study, we established a method to self-assemble DNA origami nanostructures into two-dimensional crystalline structures on planar lipid bilayer membranes. By changing the shape of DNA nanostructures and designing interactions between the DNA nanostructures, various two-dimensional crystalline structures were constructed. The self-assembled structures can be modified with heterogeneous molecules and be used as a scaffold for periodic arrangement of protein molecules and other nanostructures.
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Report
(3 results)
Research Products
(12 results)
