| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
We created a macaque model of central poststroke pain (CPSP), and investigated its behavior and brain function using a high magnetic field MRI. Functional connectivities between pain related brain regions increased after pain development. Primary motor cortex stimulation using repetitive transcranial magnetic stimulation (rTMS) alleviated hyperesthesia, and decreased functional connectivities between pain related brain regions. The findings from this study have suggested that the functional connectivity between pain related brain regions is involved in mechanisms of CPSP development and pain relief after rTMS.
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