Implantable optical diagnostic and therapeutic devices based on biophotonic LSI technology
Project/Area Number |
15K21164
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Nanobioscience
Electron device/Electronic equipment
|
Research Institution | The University of Tokyo (2016-2018) Nara Institute of Science and Technology (2015) |
Principal Investigator |
Takehara Hiroaki 東京大学, 大学院工学系研究科(工学部), 助教 (60723088)
|
Research Collaborator |
Ohta Jun
Tokuda Takashi
Sasagawa Kiyotaka
Noda Toshihiko
|
Project Period (FY) |
2015-04-01 – 2019-03-31
|
Project Status |
Completed (Fiscal Year 2018)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 体内埋植デバイス / 半導体集積回路 / ハイドロゲル材料 / 細胞応答 / バイオデバイス / 埋め込みデバイス / フレキシブルデバイス / 光導波路 / 光半導体デバイス / 光治療 / 蛍光イメージング |
Outline of Final Research Achievements |
In this research, a novel method for optical diagnosis and therapy based on the integration between biocompatible polymer materials and large-scale integration (LSI) chip technology was proposed. Implantable optical theranostic devices and implantable optical waveguides enabled regional illumination inside the body and contact imaging of biological tissues for optical diagnosis and therapy.
|
Academic Significance and Societal Importance of the Research Achievements |
光を用いて診断・治療を一体化する新たな医療技術が注目されている。本研究で確立した生体内光センシング・光治療一体化デバイス技術は、生体と親和して生体内で光を操作する手法を提供し、光を利用するバイオメディカルデバイス技術の発展に貢献する。また、半導体デバイス研究分野において本研究は、医療応用を指向した体内埋植型集積回路センサ技術という新たな応用分野の開拓に資する。
|
Report
(5 results)
Research Products
(25 results)
-
-
-
-
[Journal Article] Implantable optogenetic device with CMOS IC technology for simultaneous optical measurement and stimulation2017
Author(s)
Makito Haruta,Naoya Kamiyama,Shun Nakajima,Mayumi Motoyama,Mamiko Kawahara Yasumi Ohta,Atsushi Yamasaki,Hiroaki Takehara,Toshihiko Noda,Kiyotaka Sasagawa,Yasuyuki Ishikawa,Takashi Tokuda,Hitoshi Hashimoto,Jun Ohta
-
Journal Title
Japanese Journal of Applied Physics
Volume: 56
Issue: 5
Pages: 057001-057001
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
-
-
[Journal Article] In-vitro long-term performance evaluation and improvement in the response time of CMOS-based implantable glucose sensors2016
Author(s)
T. Tokuda, T. Kawamura, K. Masuda, T. Hirai, Hironari Takehara, Y. Ohta, M. Motoyaa, Hiroaki Takehara, T. Noda, K. Sasagawa, T. Okitsu, S. Takeuchi, and J. Ohta
-
Journal Title
IEEE Design & Test
Volume: 33
Issue: 4
Pages: 37-48
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-