Molybdenum-Catalyzed Carbon-Hydrogen Bond Functionalization
| Project/Area Number |
15K21180
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
Organic chemistry
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| Research Institution | Okayama University |
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Principal Investigator |
Asako Sobi 岡山大学, 自然科学研究科, 助教 (80737289)
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| Research Collaborator |
ISHIKAWA Sae
HAYASHI Miyuki
ISHIHARA Seina
HIRATA Keiya
KOBASHI Takaaki
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | モリブデン / 炭素－水素結合切断 / 不活性結合活性化 / カルベン / インドール / ヒドロシリル化 / アレン / 脱酸素 |
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| Outline of Final Research Achievements |
The molybdenum-catalyzed deoxygenative cyclizations of carbonyl compounds through C(sp3)-H and C(sp2)-H bond cleavage have been developed, where the carbonyl carbon functions as a carbene equivalent. The molybdenum-catalyzed hydrosilylation of allenes for synthesis of linear allylsilanes has also been developed. The origin of the unprecedented linear selectivity was revealed by DFT studies. Both the reactions showed reactivity and selectivity unique to molybdenum.
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Report
(4 results)
Research Products
(13 results)
