| Project/Area Number |
15K21237
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Tumor diagnostics
General surgery
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 乳癌 / ホルモン療法 / 効果予測 / 乳がん / 効果予測因子 |
|---|
| Outline of Final Research Achievements |
①DNA copy number abberation algorithm of pre-treatment tumor DNA showed little relationship to Ki67 decrease between pre- and post treatment.
②Whole blood RNA were analyzed by 90 cases. Test set (N=10) revealed microRNAs, which were correlated with PEPI score, such as miR503-5p, miR127-3p, miR135b-5p, miR126-3p, let7e-3, and miR647.These microRNAs had been reported as factor of cancer initiation and progression.
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