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Development of nutritional therapy aimed at prolonging the healthy life span in patients with cirrhosis after sustained virological response.

Research Project

Project/Area Number 15K21289
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Applied health science
Research InstitutionFukushima Medical University (2016-2017)
Osaka City University (2015)

Principal Investigator

HAYASHI FUMIKAZU  福島県立医科大学, 医学部, 助教 (30723291)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords慢性肝炎 / サルコペニア / 骨粗鬆症 / 運動耐容能 / 栄養学 / 慢性肝疾患 / 肝疾患 / 栄養 / 身体活動 / 肝硬変
Outline of Final Research Achievements

Sarcopenia associated with chronic liver disease is a risk of deteriorating prognosis and falling into a condition requiring long-term care. Therefore, we focused on lifestyle habits in patients with liver disease and conducted research. As a result, we showed that osteoporosis and decreased peak oxygen consumption are associated with a decrease in skeletal muscle mass. These results suggest that sarcopenia associated with liver disease is more likely to be associated with physical inactivity and nutritional factors.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (6 results) (of which Invited: 1 results)

  • [Journal Article] Loss of skeletal muscle mass in patients with chronic liver disease is related to decrease in bone mineral density and exercise tolerance2018

    • Author(s)
      Hayashi Fumikazu、Kaibori Masaki、Sakaguchi Tatsuma、Matsui Kosuke、Ishizaki Morihiko、Kwon A-Hon、Iwasaka Junji、Kimura Yutaka、Habu Daiki
    • Journal Title

      Hepatology Research

      Volume: 48 Issue: 5 Pages: 345-354

    • DOI

      10.1111/hepr.13000

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 慢性肝疾患に伴うサルコペニア・フレイルティに関する一連の検討.2018

    • Author(s)
      林史和、羽生大記.
    • Organizer
      第21回日本病態栄養学会年次学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 慢性肝疾患に伴うサルコペニアにおける筋・骨連関及び生活習慣との関連性.2018

    • Author(s)
      林史和、羽生大記.
    • Organizer
      第54回肝臓学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 慢性肝疾患に伴うサルコペニアの診断2017

    • Author(s)
      新宅令花、鈴森響子、林史和、安井洋子、羽生大記、楊和典、西川浩樹、榎本 平之、西口修平
    • Organizer
      第20回日本病態栄養学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2017-01-13
    • Related Report
      2016 Research-status Report
  • [Presentation] 抗ウイルス療法がC型慢性肝炎患者の栄養状態に及ぼす影響.2017

    • Author(s)
      山野裕加、林史和、鈴森響子、楊和典、西川浩樹、榎本平之、西口修平、安井洋子、羽生大記.
    • Organizer
      第40回日本栄養アセスメント研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] SVR後C型肝炎患者の栄養学的な評価と今後のマネージメント2017

    • Author(s)
      林 史和、羽生 大記
    • Organizer
      日本消化器病学会近畿支部 第106回例会
    • Place of Presentation
      大阪国際交流センター
    • Related Report
      2016 Research-status Report
  • [Presentation] 肝切除術前肝がん患者のサルコペニアは、骨密度・運動耐容能の減少と関連する2016

    • Author(s)
      林 史和、海掘 昌樹、羽生 大記
    • Organizer
      第52回日本肝臓学会総会
    • Place of Presentation
      東京ベイ幕張ホール(千葉県・千葉市)
    • Year and Date
      2016-05-19
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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