Identificaition of novel tyrosine kinase fusion genes in gynecological tumors

Research Project

Project/Area Number	15K21606
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Obstetrics and gynecology Tumor diagnostics
Research Institution	Japanese Foundation for Cancer Research
Principal Investigator	SAKATA Seiji 公益財団法人がん研究会, がん研究所分子標的病理プロジェクト, 研究員 (00617433)
Project Period (FY)	2015-04-01 – 2017-03-31
Project Status	Completed (Fiscal Year 2016)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	チロシンキナーゼ / 融合遺伝子
Outline of Final Research Achievements	We discovered a tyrosine kinase fusion gene in 4 gynecological tumors by fluorescence in situ hybridization and real-time PCR. A point mutation of the tyrosine kinase was found in 0.8% of uterine cervical tumors.

Report

(3 results)