Synchronized behavior analysis with delayed-mirror system in ASD model primate
| Project/Area Number |
15K21651
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic / Social brain science
Statistical science
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| Research Institution | National Institutes for Quantum and Radiological Science and Technology (2017)
National Center of Neurology and Psychiatry (2015-2016) |
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Principal Investigator |
Mimura Koki 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 脳機能イメージング研究部, 研究員(任常) (60747377)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 社会性 / 同調 / 霊長類 / 自閉症 / 空間測定 / 自由行動 / 行動神経学 / 計算モデル |
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| Outline of Final Research Achievements |
In this study, we focused on synchronized behavior, one of the significant part of social ability. First, we developed new autism spectrum disorder (ASD) model animal in common marmoset (Callithrix jacchus) with exposed valproate in utero. These animals represented significant atypical brain structure in neonate and confused familial vocalization (Mimura et al., in press). Then, to quantify free moving synchronized behavior, we developed a new motion tracking system by using multi-depth cameras and machine learning algorithm. As a result, we succeeded to track head, body, hip, and face direction of 3D free moving common marmoset without any kind of body markers. These high resolution free movement database could be the basis of mutual interaction analysis with statistical contextual segmentation techniques.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] 3D reconstruction of brain section images for creating axonal projection maps in marmosets.2017
Author(s)
Abe H, Tani T, Mashiko H, Kitamura N, Miyakawa N, Mimura K, Sakai K, Suzuki W, Kurotani T, Mizukami H, Watakabe A, Yamamori T, Ichinohe N.
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Journal Title
J Neurosci Methods
Volume: 286
Pages: 102-113
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] 3D-Tracker, an open-source 3D video based behavioral analysis system for laboratory animals for neuroscience2017
Author(s)
J. Matsumoto, H. Nishimaru, Y. Takamura, K. Mimura, A. Asaba, W. Suzuki, N. Ichinohe, T. Minamimoto, T. Ono, H. Nishijo
Organizer
Neuroscience 2017
Related Report
Int'l Joint Research
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