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Implantable glucose sensor toward fully implantable glucose monitoring system(Fostering Joint International Research)

Research Project

Project/Area Number 15KK0209
Research Category

Fund for the Promotion of Joint International Research (Fostering Joint International Research)

Allocation TypeMulti-year Fund
Research Field Electron device/Electronic equipment
Research InstitutionNara Institute of Science and Technology

Principal Investigator

Tokuda Takashi  奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授 (50314539)

Research Collaborator Sawan Mohamad  モントリオール理工科大学, Depart of Electrical Engineering, 教授
Ohta Jun  奈良先端科学技術大学院大学, 先端科学技術研究科, 教授
Sasagawa Kiyotaka  奈良先端科学技術大学院大学, 先端科学技術研究科, 助教
Haruta Makito  奈良先端科学技術大学院大学, 先端科学技術研究科, 助教
Noda Toshihiko  豊橋技術科学大学, エレクトロニクス先端融合研究所, 准教授
Project Period (FY) 2016 – 2018
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
KeywordsCMOS / 生体埋め込みデバイス / グルコースセンサ / ワイヤレス電力伝送 / エナジーハーベスティング / CMOSセンサ / ワイヤレス
Outline of Final Research Achievements

This project was performed to develop an ultra-small power receiving platform for implantable bioelectornics. The research was partly done under a collaboration with Prof. Mohamad Sawan in Polytechnique Montreal. Considering the requirements for ultra-small implantable lectronic devices, An optical powering scheme was chosen in the project. CMOS-based circuits, as well as integrated power receiving chip were designed and characterized. Some of significantly essential function were demonstrated successfully and basic characteristics of the proposed optical powering platform were analyzed and published.

Academic Significance and Societal Importance of the Research Achievements

本研究の成果により、超小型の生体内デバイスに利用可能なワイヤレス電力伝送技術が実現できた。生体内で赤色もしくは赤外光から電力を得て蓄積し、一回の動作に必要な電力がたまれば負荷を駆動するという方式は、単純な回路で高い電圧の回路を駆動するのに有効な新技術である。さらには複数の電力パルスにわたるシーケンス動作を可能とする回路構成も実現・実証した。これにより生体内センシングの機能性実現に向けた基礎的な機能を実現したといえる。実現された技術は、間欠駆動するマイクロデバイス系に利用可能であるため、IoTシステムにおける安価な端末駆動技術にも応用できると期待される。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (17 results)

All 2019 2018 2017 2016

All Int'l Joint Research (1 results) Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 2 results) Book (1 results)

  • [Int'l Joint Research] モントリオール理工科大学(カナダ)2016

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Design Optimization of CMOS Control Circuit for Integrated Photovoltaic Power Transfer2018

    • Author(s)
      T. Tokuda, T. Ishizu, N. Wuthibenjaphonchai M. Haruta, T. Noda, K. Sasagawa, M. Sawan, and . Ohta
    • Journal Title

      Sensors and Materials

      Volume: 30 Issue: 10 Pages: 2343

    • DOI

      10.18494/SAM.2018.1945

    • ISSN
      0914-4935, 2435-0869
    • Year and Date
      2018-10-25
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 1 mm3-sized Optical Neural Stimulator based on CMOS Integrated Photovoltaic Power Receiver2018

    • Author(s)
      T. Tokuda, T. Ishizu, W. Nattakarn, M. Haruta, T. Noda, K. Sasagawa, M. Sawan, and J. Ohta
    • Journal Title

      AIP Advances

      Volume: 8 Issue: 4 Pages: 45018-45018

    • DOI

      10.1063/1.5024243

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] CMOS-based optical energy harvesting circuit for biomedical and Internet of Things devices2018

    • Author(s)
      Wuthibenjaphonchai Nattakarn, Takaaki Ishizu, Makito Haruta, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Mohamad Sawan and Jun Ohta
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 57 Issue: 4S Pages: 04FM05-04FM05

    • DOI

      10.7567/jjap.57.04fm05

    • NAID

      210000148977

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] In-vitro long-term performance evaluation and improvement in the response time of CMOS-based implantable glucose sensors2016

    • Author(s)
      T. Tokuda, T. Kawamura, K. Masuda, T. Hirai, Hironari Takehara, Y. Ohta, M. Motoyaa, Hiroaki Takehara, T. Noda, K. Sasagawa, T. Okitsu, S. Takeuchi, and J. Ohta
    • Journal Title

      IEEE Design & Test

      Volume: 33 Issue: 4 Pages: 37-48

    • DOI

      10.1109/mdat.2016.2560137

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] CMOS技術による生体埋植マイクロデバイス2016

    • Author(s)
      徳田 崇, 太田 淳
    • Journal Title

      応用物理

      Volume: 65 Pages: 889-894

    • NAID

      130007715244

    • Related Report
      2016 Research-status Report
  • [Presentation] Wireless Sticker-like Health-monitoring Devices Operated by Optical Power Transfer2019

    • Author(s)
      Nattakarn Wuthibenjaphonchai・Thanet Pakpuwadon・川崎祐久・春田牧人・笹川清隆・徳田 崇・太田 淳
    • Organizer
      平成31年電気学会全国大会(日本、北海道科学大学)
    • Related Report
      2018 Annual Research Report
  • [Presentation] Battery-Free Sticker-Like Device for Health Monitoring Operated by Optical Power Transfer2018

    • Author(s)
      N. Wuthibenjaphonichai, M Haruta, T. Noda, K. Sasagawa, T. Tokuda, M. Sawan, S. Carrara, and J. Ohta
    • Organizer
      2018 IEEE Biomedical Circuits and Systems Conference (BioCAS2018), Cleveland, USA
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Live Demonstration: IoT Micronode with Optical ID Transmission Capability Operated by Optical Energy Harvesting2018

    • Author(s)
      T. Tokuda, W. Nattakarn, T. Ishizu, M. Haruta, T. Noda, K. Sasagawa, and J. Ohta
    • Organizer
      IEEE International Symposium on Circuit and Systems, Florence, Italy,
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光電力伝送によるバッテリレス生体埋植光刺激デバイス2018

    • Author(s)
      川野裕祐、石津岳明、春田牧人、野田俊彦、笹川清隆、徳田崇、太田淳
    • Organizer
      平成30年電気学会全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] CMOS-based Optical Energy Harvesting Circuit for Bio-implantable and IoT Devices2017

    • Author(s)
      Nattakarn Wuthibenjaphonchai, Makito Haruta, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, and Jun Ohta
    • Organizer
      第64回応用物理学会春季学術講演会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2017-03-14
    • Related Report
      2016 Research-status Report
  • [Presentation] CMOS-base optical energy harvesting for biomedical and IoT devices2017

    • Author(s)
      Wuthibenjaphonchai Nattakarn, Makito Haruta, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, and Jun Ohta
    • Organizer
      日本光学会年次学術講演会
    • Related Report
      2017 Research-status Report
  • [Presentation] 光エナジーハーベスティングによる生体埋植型光刺激デバイス2017

    • Author(s)
      石津 岳明、N. Wuthibenjaphonchai、春田 牧人、野田 俊彦、笹川 清隆、徳田 崇、太田 淳
    • Organizer
      第78回応用物理学会秋季講演会
    • Related Report
      2017 Research-status Report
  • [Presentation] CMOS-based optical energy harvesting circuit for medical and iot devices2017

    • Author(s)
      N. Wuthibenjaphonchai, M. Haruta, T. Noda, K. Sasagawa, T. Tokuda, and J. Ohta
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Design and Evaluation of Implantable CMOS Chips2016

    • Author(s)
      T. Tokuda, T. Noda, K. Sasagawa, and J. Ohta
    • Organizer
      IEEE/ACM Workshop on Variability Modeling and Characterization
    • Place of Presentation
      Doubletree Hotel, Austin, TX, USA
    • Year and Date
      2016-11-10
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] CMOS-based implantable biodevices2016

    • Author(s)
      T. Tokuda
    • Organizer
      Inviter Seminar of The Quebec IEEE Engineering in Medicine and Biology / Circuits and Systems Chapter
    • Place of Presentation
      Laval University, Quebec City, Canada
    • Year and Date
      2016-10-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] 『IoTを指向するバイオセンシング・デバイス技術』第2章3節2016

    • Author(s)
      徳田 崇, 竹原 宏明, 野田 俊彦, 笹川 清隆, 太田 淳
    • Total Pages
      8
    • Publisher
      シーエムシー出版
    • Related Report
      2016 Research-status Report

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Published: 2016-10-04   Modified: 2020-03-30  

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