Manipulation of inorganic nanosheets by molecular information of DNA(Fostering Joint International Research)
| Project/Area Number |
15KK0217
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| Research Category |
Fund for the Promotion of Joint International Research (Fostering Joint International Research)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Inorganic industrial materials
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| Research Institution | Fukuoka Institute of Technology |
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Principal Investigator |
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| Research Collaborator |
Davidson Patrick Université Paris-Sud, Laboratoire de Physique des Solides, Professor
Asanuma Hiroyuki
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| Project Period (FY) |
2016 – 2018
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
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| Keywords | ナノシート / DNA / 液晶 / コロイド / ssDNA / 小角散乱法 |
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| Outline of Final Research Achievements |
Strong liquid crystallinity was induced by adding a small amount of DNA into isotropic clay mineral nanosheet colloids. This phenomenon was explained by unexpected DNA-nanosheet attractions. Next, we investigated immobilization of fluorescence-labeled ssDNA on nanosheet surfaces through covalent bond. The reaction product was obtained by the reaction of freeze-dried nanosheets with silylation reagents. By fluorescence microscopy and other techniques, immobiliation of the ssDNA was confirmed. Further, the immobilizaed ssDNA was found to form double stranded DNA with the ssDNA with complementary sequences.
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| Academic Significance and Societal Importance of the Research Achievements |
無機ナノシートやその集積体は、触媒能や光機能などのさまざまな特性を示すことから、機能材料を構築するための基礎部品として注目を集めてきた。一方、DNAは自在に連結可能な塩基配列に基づく「分子情報」を有しており、分子コンピューティングや、プログラマブルなナノ構造構築などのDNAテクノロジー研究が盛んに行われている。本研究では、DNAとナノシートの複合化を行うための基礎的知見を得ることができ、学術的に大きな進展がえられた。今後、ナノシートとDNAに基づく様々な機能材料の設計が可能となり、新しい省エネ材料や高性能デバイスなどが開発されることが期待され、社会的にも大きな意義のある成果である。
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Report
(4 results)
Research Products
(118 results)
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[Journal Article] A Facile Synthesis of Cd(Oh)2-RGO Nanocomposites for the Practical Electrochemical Detection of Acetaminophen2016
Author(s)
Sakthivel, M., Sivakumar, M., Chen, S.-M., Hou, Y.-S., Veeramani, V., Madhu, R. & Miyamoto, N.
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Journal Title
Electroanalysis
Volume: 29
Issue: 1
Pages: 280-286
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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