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Coevolution of primate diet and gut microbe(Fostering Joint International Research)

Research Project

Project/Area Number 15KK0256
Research Category

Fund for the Promotion of Joint International Research (Fostering Joint International Research)

Allocation TypeMulti-year Fund
Research Field Ecology/Environment
Research InstitutionKyoto University

Principal Investigator

Hanya Goro  京都大学, 霊長類研究所, 准教授 (40444492)

Research Collaborator SHIMIZU Kentaro  チューリッヒ大学, 進化生物・環境学研究所, 准教授
Ngomanda Alfred  Institut de la Recherche en Ecologie Tropicale, 進化生物・Institut de la Recherche en Ecologie Tropicale, 所長
ZHANG Peng  中山大学, 人類学部門, 教授
FANG Pengfei  中山大学, 生物学部門, 教授
Malaivijitnond Suchinda  
Project Period (FY) 2016 – 2018
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Keywords腸内細菌 / 霊長類 / 共進化 / 食性 / 系統 / 消化 / 16S rRNA / 発酵 / トランスクリプトーム / 次世代シーケンス
Outline of Final Research Achievements

The aim of this study is to clarify how gut microbe has coevolved with primate diet, with special reference to the digestive function, both at the ecological and evolutionary time scales. For that purpose, first, we examined the relationship between primate phylogeny and/or digestive system and the similarity of gut microbe species composition by collecting samples from 31 species of non-human primates living in Japan, China, Thailand, Malaysia, Uganda and Gabon. Second, in order to understand the digestive function of the gut microbe, we conducted in vitro fermentation assay and genetic analysis for the fresh fecal samples collected for Japanese macaques living in the highland and lowland of Yakushima, where they have contrasting diets.

Academic Significance and Societal Importance of the Research Achievements

近年、腸内細菌が消化や免疫機能、神経系と関連して、ヒトの健康に大きな影響を与えていることが注目されている。ヒトは進化の過程できわめて特殊な食性を獲得しており、とくに現代日本人は、料理された、栄養価の高い食事を恒常的に摂取している点で、ほかのどの動物とも、ヒトのこれまでの進化過程のいずれとも異なっている。動物が腸内細菌をどのように利用して暮らしているかを理解するためには、より厳しく、季節的に大きく変動する環境で暮らす、多数の動物種を対象にした研究が不可欠である。多数の種の腸内細菌を比較し、さらに腸内細菌の消化機能を明らかにする本研究は、きわめて学術的価値の高いものである。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (27 results)

All 2018 2017 2016 Other

All Int'l Joint Research (3 results) Journal Article (16 results) (of which Int'l Joint Research: 9 results,  Peer Reviewed: 16 results,  Open Access: 6 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) Book (1 results) Remarks (2 results)

  • [Int'l Joint Research] 中山大学(中国)2018

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Institut de la Recherche en Ecologie Tropicale(ガボン)2017

    • Year and Date
      2017-02-08
    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] チューリヒ大学進化生物・環境学研究所(スイス)2016

    • Year and Date
      2016-09-29
    • Related Report
      2018 Annual Research Report
  • [Journal Article] Within-Population Variations in Home Range Use and Food Patch Use of Japanese Macaques: A Perspective of Intergroup Hostility2018

    • Author(s)
      Kurihara Yosuke、Hanya Goro
    • Journal Title

      Folia Primatologica

      Volume: 89 Issue: 6 Pages: 397-414

    • DOI

      10.1159/000493574

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Seasonal variation of energy expenditure in Japanese macaques (Macaca fuscata)2018

    • Author(s)
      Sha John Chih Mun、Kurihara Yosuke、Tsuji Yamato、Take Makiko、He Tianmeng、Kaneko Akihisa、Suda-Hashimoto Naoko、Morimoto Mayumi、Natsume Takayoshi、Zahariev Alexandre、Blanc St?phane、Hanya Goro
    • Journal Title

      Journal of Thermal Biology

      Volume: 76 Pages: 139-146

    • DOI

      10.1016/j.jtherbio.2018.07.009

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Improving the standards for gut microbiome analysis of fecal samples: insights from the field biology of Japanese macaques on Yakushima Island2018

    • Author(s)
      Hayakawa Takashi、Sawada Akiko、Tanabe Akifumi S.、Fukuda Shinji、Kishida Takushi、Kurihara Yosuke、Matsushima Kei、Liu Jie、Akomo-Okoue Etienne-Francois、Gravena Waleska、Kashima Makoto、Suzuki Mariko、Kadowaki Kohmei、Suzumura Takafumi、Inoue Eiji、Sugiura Hideki、Hanya Goro、Agata Kiyokazu
    • Journal Title

      Primates

      Volume: 59 Issue: 5 Pages: 423-436

    • DOI

      10.1007/s10329-018-0671-x

    • NAID

      40021661058

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Activity of wild Japanese macaques in Yakushima revealed by camera trapping: Patterns with respect to season, daily period and rainfall2018

    • Author(s)
      Hanya G, Otani Y, Hongo S, Honda T, Okamura H, Higo Y
    • Journal Title

      PLoS ONE

      Volume: 13 Issue: 1 Pages: e0190631-e0190631

    • DOI

      10.1371/journal.pone.0190631

    • NAID

      120006460049

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Morphometric and Genetic Determination of Age Class and Sex for Fecal Pellets of Sika Deer (Cervus nippon)2017

    • Author(s)
      Hanya Goro、Naito Senri、Namioka Erina、Ueda Yosuke、Sato Yo、Pastrana Josue Alejandro、He Tianmeng、Yan Xiaochan、Saito Miho、Costa Raquel Filomena Pereira、Allanic Morgane、Honda Takeaki、Kurihara Yosuke、Yumoto Takakazu、Hayakawa Takashi
    • Journal Title

      Mammal Study

      Volume: 42 Issue: 4 Pages: 1-8

    • DOI

      10.3106/041.042.0406

    • NAID

      210000182462

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Thyroid hormone fluctuations indicate a thermoregulatory function in both a tropical (Alouatta palliata) and seasonally cold-habitat (Macaca fuscata) primate2017

    • Author(s)
      Thompson Cynthia L.、Powell Brianna L.、Williams Susan H.、Hanya Goro、Glander Kenneth E.、Vinyard Christopher J.
    • Journal Title

      American Journal of Primatology

      Volume: 79 Issue: 11

    • DOI

      10.1002/ajp.22714

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Estimating activity of Japanese macaques (Macaca fuscata) using accelerometers2017

    • Author(s)
      Sha John C. M.、Kaneko Akihisa、Suda-Hashimoto Naoko、He Tianmeng、Take Makiko、Peng Zhang、Hanya Goro
    • Journal Title

      American Journal of Primatology

      Volume: 79 Issue: 10

    • DOI

      10.1002/ajp.22694

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Comparison of energy balance between two different-sized groups of Japanese macaques (Macaca fuscata yakui)2017

    • Author(s)
      Kurihara Yosuke、Hanya Goro
    • Journal Title

      Primates

      Volume: 58 Issue: 3 Pages: 413-422

    • DOI

      10.1007/s10329-017-0607-x

    • NAID

      40021236811

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes of Abundance of Japanese Macaques in Yakushima over the Past 20 Years2017

    • Author(s)
      宮田 晃江、好廣 眞一、高畑 由起夫、萬田 正治、古市 剛史、栗原 洋介、早石 周平、半谷 吾郎
    • Journal Title

      Primate Research

      Volume: 33 Issue: 1 Pages: 35-42

    • DOI

      10.2354/psj.33.001

    • NAID

      130005865520

    • ISSN
      0912-4047, 1880-2117
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Factors Affecting Leaf Selection by Foregut-fermenting Proboscis Monkeys: New Insight from in vitro Digestibility and Toughness of Leaves2017

    • Author(s)
      Matsuda I, Clauss M, Tuuga A, Sugau J, Hanya G, Yumoto T, Bernard H, and Hummel J
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 42774-42774

    • DOI

      10.1038/srep42774

    • NAID

      120005997744

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 屋久島のニホンザル生息状況の過去20年間の変化2017

    • Author(s)
      宮田晃江、好廣眞一、高畑由起夫、萬田正治、古市剛史、栗原洋介、早石周平、半谷吾郎
    • Journal Title

      霊長類研究

      Volume: 印刷中

    • NAID

      130005865520

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Draft genome sequences of Sarcina ventriculi isolated from wild Japanese macaques in Yakushima island2016

    • Author(s)
      Ushida K, Tsuchida S, Ogura Y, Hayashi T, Sawada A, Hanya G
    • Journal Title

      Genome Announcements

      Volume: 4 Issue: 1 Pages: 1-2

    • DOI

      10.1128/genomea.01694-15

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Seasonal and inter-island variation in the foraging strategy of the critically endangered Red-headed Wood Pigeon Columba janthina nitens in disturbed island habitats derived from high-throughput sequencing.2016

    • Author(s)
      Ando H, Suzuki S, Horikoshi K, Suzuki H, Umehara S, Yamasaki M, Hanya G, Inoue-Murayama M, Isagi Y
    • Journal Title

      Ibis

      Volume: 158 Issue: 2 Pages: 291-304

    • DOI

      10.1111/ibi.12345

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Seasonally consistent small home range and long ranging distance in Presbytis rubicunda in Danum Valley, Borneo2016

    • Author(s)
      Hanya G, Bernard H
    • Journal Title

      International Journal of Primatology

      Volume: 37 Issue: 3 Pages: 390-404

    • DOI

      10.1007/s10764-016-9907-z

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Frugivore assemblage of Ficus superba in a warm-temperate forest in Yakushima, Japan2016

    • Author(s)
      Hamada A, Hanya G
    • Journal Title

      Ecological Research

      Volume: 31 Issue: 6 Pages: 903-911

    • DOI

      10.1007/s11284-016-1398-z

    • NAID

      40021004163

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Species Richness and Distribution of Primates in Disturbed and Converted Forest Landscapes in Northern Borneo2016

    • Author(s)
      Bernard H, Bili R, Matsuda I, Hanya G, Wearn OR, Wong A, and Ahmad AH
    • Journal Title

      Tropical Conservation Science

      Volume: 9 Issue: 4 Pages: 1-11

    • DOI

      10.1177/1940082916680104

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 屋久島に生息するニホンザルの高順位個体は採食競合による利益を得ているか2017

    • Author(s)
      栗原洋介、半谷吾郎
    • Organizer
      第64回日本生態学会大会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2017-03-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 屋久島山頂部におけるヤクシマザルの季節移動2017

    • Author(s)
      本田剛章、半谷吾郎
    • Organizer
      第64回日本生態学会大会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2017-03-15
    • Related Report
      2016 Research-status Report
  • [Presentation] カメラトラップで明らかになった野生ニホンザルの活動時間2017

    • Author(s)
      半谷吾郎、大谷洋介、本郷峻、本田剛章、岡村弘樹、肥後悠馬
    • Organizer
      第33回日本霊長類学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 屋久島海岸域に生息するニホンザルにおけるエネルギー収支の季節変化2016

    • Author(s)
      栗原洋介、半谷吾郎
    • Organizer
      第32回日本霊長類学会大会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
  • [Presentation] ボルネオ島・ダナムバレーのレッドリーフモンキーの遊動パターン2016

    • Author(s)
      半谷吾郎、Henry Bernard
    • Organizer
      第32回日本霊長類学会大会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
  • [Book] 旅するミシン店2018

    • Author(s)
      半谷吾郎、松原始
    • Total Pages
      320
    • Publisher
      サルと屋久島: ヤクザル調査隊とフィールドワーク
    • Related Report
      2018 Annual Research Report
  • [Remarks] 半谷吾郎

    • URL

      http://www.pri.kyoto-u.ac.jp/shakai-seitai/ecolcons/hanya/

    • Related Report
      2018 Annual Research Report
  • [Remarks] 半谷吾郎

    • URL

      http://www.pri.kyoto-u.ac.jp/sections/ecolcons/hanya/

    • Related Report
      2017 Research-status Report 2016 Research-status Report

URL: 

Published: 2016-10-04   Modified: 2020-03-30  

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