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System study on higher-order brain functions

Research Project

Project/Area Number 16068101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionTamagawa University (2010)
Kyoto Prefectural University of Medicine (2004-2009)

Principal Investigator

KIMURA Minoru  玉川大学, 脳科学研究所, 教授 (40118451)

Co-Investigator(Kenkyū-buntansha) 小松 英彦  生理学研究所, 生体情報研究系, 教授 (00153669)
田中 啓治  独立行政法人理化学研究所, 脳科学総合研究センター, 領域ディレクター (00221391)
福島 菊郎  北海道大学, 大学院・医学研究科, 教授 (70091486)
川人 光男  株式会社国際電気通信基礎技術研究所, 脳情報研究所, 所長 (10144445)
泰羅 雅登  日本大学, 大学院・総合科学研究科, 教授 (50179397)
Co-Investigator(Renkei-kenkyūsha) KOMATSU Hidehiko  生理学研究所, 生体情報研究系, 教授 (00153669)
TANAKA Keiji  独立行政法人理化学研究所, 脳科学総合研究センター, 領域ディレクター (00221391)
FUKUSHIMA Kikuro  北海道大学, 大学院・医学系研究科, 教授 (70091486)
KAWATO Mitsuo  株式会社国際電気通信基礎技術研究所, 脳情報研究所, 所長 (10144445)
TAIRA Masato  日本大学, 大学院・総合科学研究科, 教授 (50179397)
SAKAI Kuniyoshi  東京大学, 大学院・総合文化研究科, 准教授 (10251216)
Project Period (FY) 2004 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥28,200,000 (Direct Cost: ¥28,200,000)
Fiscal Year 2010: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2009: ¥4,700,000 (Direct Cost: ¥4,700,000)
Fiscal Year 2008: ¥4,300,000 (Direct Cost: ¥4,300,000)
Fiscal Year 2007: ¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2006: ¥4,400,000 (Direct Cost: ¥4,400,000)
Fiscal Year 2005: ¥4,600,000 (Direct Cost: ¥4,600,000)
Fiscal Year 2004: ¥3,500,000 (Direct Cost: ¥3,500,000)
Keywords認知と記憶 / 行動と運動 / 情動 / 思考・推論 / 言語 / 脳の作動原理 / 高次脳機能 / 情報認知 / 大脳 / コミュニケーション
Research Abstract

中核となる5つの研究項目において高い成果を得た。情報認知においては、物体の形、色、奥行きなどの特徴を抽出する神経回路メカニズムと分子的基盤を網膜、視床、大脳皮質視覚領・側頭葉の神経回路と機能モジュールにおいて明らかにする知見、物体のカテゴリー、注意や輝度による判断の大脳皮質側頭葉の情報処理原理について高水準の知見が得られた。行動と運動においては、運動の企画と制御、ゴール指向的行動とその障害における大脳皮質前頭葉と小脳の役割について、感覚情報処理から運動の企画に関わる脊髄、視床、大脳基底核、大脳皮質メカニズムの理解について顕著な成果が得られた。情動においては、大脳基底核、視床、大脳皮質、脳幹における報酬価値、動機づけの表現、行動選択への関与の様式、情動に関わる神経ペプチドの作用の理解が格段に進歩した。大脳による高次情報処理においては、思考、推論、意志決定の神経機構、認知表象の脳内再構成の神経機構などの過程、複雑問題解決プロセス、直感的思考、帰納的推論、意思決定や行動選択、ルール表象の成立、認知表象の脳内再構成の理解に繋がる顕著な成果が得られた。言語では、人間の大脳皮質における「文法中枢」の存在の証明、「文法・文章理解・単語・音韻」を言語野の機能分化に対応させた大脳皮質における新しい「言語地図」を提案するなどの成果が得られた。これらの高い成果は、Nature,Scienceをはじめとするトップジャーナルに報告され、この分野の研究に強いインパクトを与えると共に、神経難病の病因や治療法について科学的な根拠を提供した。これらの成果については中間評価ヒアリングや進捗状況報告書において文部科学省に報告してきたところであるが、22年度においてこの成果をとりまとめ、350ページの成果とりまとめ冊子として作成し、領域内・外に幅広く公表、公開した。

Report

(8 results)
  • 2010 Annual Research Report
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (93 results)

All 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article (61 results) (of which Peer Reviewed: 47 results) Presentation (19 results) Book (10 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] Inactivation of the putamen selectively impairs reward history-based action selection.2011

    • Author(s)
      Muranishi M.
    • Journal Title

      Exp Brain Res.

      Volume: 209(2) Pages: 235-246

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Juxtacellular labeling of tonically active neurons and phasically active neurons in the rat striatum.2010

    • Author(s)
      Inokawa H.
    • Journal Title

      Neuroscience

      Volume: 168(2) Pages: 395-404

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] View-invariant object recognition ability develops after discrimination, not mere exposure, at several viewing angles.2010

    • Author(s)
      Yamashita W.
    • Journal Title

      European Journal of neuroscience

      Volume: 31 Pages: 327-335

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Opposing effects of contextual surround in human early visual cortex revealed by functional magnetic resonance imaging with continuously modulated visual stimuli.2010

    • Author(s)
      Tanaka K.
    • Journal Title

      Journal of neuroscience

      Volume: 30 Pages: 3264-3270

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional and histological properties of caudal intrapariental area of macaque monkey.2010

    • Author(s)
      Katsuyama N.
    • Journal Title

      Neuroscience

      Volume: 167 Pages: 1-10

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Context-dependent place-selective response of the neurons in the medial parietal region of macaque monkeys.2010

    • Author(s)
      Sato N.
    • Journal Title

      Cerebral cortex

      Volume: 20 Pages: 846-858

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic readout of behaviorally relevant signals from area MT during task switching.2009

    • Author(s)
      Sasaki R., Uka T.
    • Journal Title

      Neuron 62

      Pages: 147-157

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture.2009

    • Author(s)
      Matsuki, T., Nomiyama, M, Takahira, H., Hirashima, N., Kilduff, T.S., Kunita, S., Takahashi, S., Yagami, K., Bettler, B., Yanagisawa, M., Sakurai, T.
    • Journal Title

      Proc Natl Acad Sci USA 106(11)

      Pages: 4459-4464

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor GPR109B.2009

    • Author(s)
      Irukayama-Tomobe, Y, Tanaka, H., Yokomizo, T., Hashidate-Yoshida, T., Yanagisawa, M., Sakurai, T.
    • Journal Title

      Proc Natl Acad Sci USA 106(10)

      Pages: 3930-3934

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Task-specific signal transmission from prefrontal cortex in visual selective attention.2009

    • Author(s)
      Morishima Y, Akaishi R, Yamada Y, Okuda J, Toma K, Sakai K.
    • Journal Title

      Nat Neurosci 12

      Pages: 85-91

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuronal encoding of reward value and direction of actions in the primate putamen.2009

    • Author(s)
      Hori Y, Minamimoto T., Kimura M.(研究代表者)
    • Journal Title

      J.Neurophysiol. 102(6)

      Pages: 3530-3543

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Memory and decision making in the frontal cortex during visual motion processing for smooth pursuit eye movements.2009

    • Author(s)
      Shichinohe N, Akao T, Kurkin S, Fukushima J, Kaneko CR., Fukushima K.(連携研究者)
    • Journal Title

      Neuron 62(5)

      Pages: 717-732

    • NAID

      120001390974

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Condition-dependent and condition-independent target selection in the macaque posterior parietal cortex.2009

    • Author(s)
      Ogawa T., Komatsu H.(連携研究者)
    • Journal Title

      J.Neurophysiol. 101

      Pages: 721-736

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Conflict-induced behavioural adjustment : a clue to the executive functions of the prefrontal cortex.2009

    • Author(s)
      Mansouri FA, Tanaka K., Buckley MJ.(連携研究者)
    • Journal Title

      Nat.Rev.Neurosci. 10(2)

      Pages: 141-152

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disclosing concealed information on the basis of cortical activations.2009

    • Author(s)
      Nose I, Murai J., Taira M.(連携研究者)
    • Journal Title

      Neuroimage 44

      Pages: 1380-1386

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The cortical dynamics in building syntactic structures of sentences : An MEG study in a minimal-pair paradigm.2009

    • Author(s)
      Iijima K, Fukui N., Sakai KL.(連携研究者)
    • Journal Title

      NeuroImage 44

      Pages: 1387-1396

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of the thalamic CM-PF complex-Basal ganglia circuit in externally driven rebias of action.2009

    • Author(s)
      Minamimoto T, Hod Y. & Kimura M.
    • Journal Title

      Brain Research Bulletin 78

      Pages: 75-79

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eye-pursuit and re-afferent head movement signals carried by pursuit neurons in the caudal part of the frontal eye fields during head-free pursuit2009

    • Author(s)
      Fukushima K, Kasahara S, Akao T, Kurkin S, Fukushima J. & Peterson BW.
    • Journal Title

      Cerebral Cortex 19

      Pages: 263-275

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bistble swiched for synaptic plasticity2009

    • Author(s)
      Ogasawara H, & Kawato M.
    • Journal Title

      Science Signaling 2

      Pages: 7-7

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A parametric relief signal in human ventrolateral prefrontal cortex2009

    • Author(s)
      Fujiwara J, Tobler PN, Taira M, lijima T. & Tsutsui K.
    • Journal Title

      Neuroimage 44

      Pages: 1163-1170

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The cortical dynamics in building syntactic structures of sentences : An MEG study in a minimal-pair paradigm.2009

    • Author(s)
      lijima K, Fukui N. & Sakai KL.
    • Journal Title

      Neuroimage 44

      Pages: 1387-1396

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reward prediction based on stimulus categorization in primate lateral prefrontal cortex.2008

    • Author(s)
      Pan X, Sawa K, Tsuda I, Tsukada M., Sakagami M.
    • Journal Title

      Nature Neurosci 11

      Pages: 703-712

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two distinct activity patterns of fast-spiking interneurons during neocortical UP-states.2008

    • Author(s)
      Puig MV, Ushimaru M., Kawaguchi Y.
    • Journal Title

      Proc Natl Acad Sci USA 105

      Pages: 8428-8433

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Matching categorical object representations in inferior temporal cortex of man and monkey2008

    • Author(s)
      Kriefeskorte N, Mur M, Ruff DA, Kiani R, Bodurka J, Esteky H, Tanaka K, Bandettini PA.
    • Journal Title

      Neuron 60

      Pages: 1126-1141

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between color discrimination and neural responses in the inferior temporal cortex of the monkey2008

    • Author(s)
      Matsumora T, Koida K. & Komatsu H.
    • Journal Title

      J Neurophysiol 100

      Pages: 3361-3374

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of the cerebellar dorsal vermis in vergence eye movements in monkeys2008

    • Author(s)
      Nitta T, Akao T, kurkin S, Fukushima K.
    • Journal Title

      Cerebral Cortex 18

      Pages: 1042-1057

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of task demands on the responses of color-selective neurons in the inferior temporal cortex.2007

    • Author(s)
      Koida K, Komatsu H.
    • Journal Title

      Nature Neurosci 10

      Pages: 108-116

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Categorization of behavioral sequences in the prefrontal cortex.2007

    • Author(s)
      Shima K, Isoda M, Mushiake H, Tanji J
    • Journal Title

      Nature 445

      Pages: 17183266-17183266

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Medial Prefrontal Cell Activity Signaling Prediction Errors of Action Values.2007

    • Author(s)
      Matsumoto M, *Matsumoto K, Abe H, Tanaka K.
    • Journal Title

      Nature Neurosci 10

      Pages: 647-656

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A temporal frequency-dependent functional architecture in human V1 revealed by high-resolution fMRI.2007

    • Author(s)
      Sun P, Ueno K, Waggoner RA, Gardner JL, Tanaka K, Cheng K.
    • Journal Title

      Nature Neurosci. 10

      Pages: 1404-1406

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mnemonic function of lateral prefrontal cortex in conflict-induced behavioral adjustment.2007

    • Author(s)
      *Mansouri FA, Buckley MJ, Tanaka K.
    • Journal Title

      Science 318

      Pages: 987-990

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] History- and current instruction-based coding of forthcoming behavioral outcomes in the striatum2007

    • Author(s)
      Yamada H, Matsumoto N, Kimura, M.
    • Journal Title

      J Neurophysiol 98

      Pages: 3557-3567

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mnemonic function of lateral prefrontal cortex in conflict-induced behavioral adjustment2007

    • Author(s)
      Mansouri FA, Buckley MJ, Tanaka K.
    • Journal Title

      Science 318

      Pages: 987-990

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficient reinforcement learning:computational theories,neuroscience and robotics2007

    • Author(s)
      Kawato M, Samejima K.
    • Journal Title

      Curr Opin Neurobiol 17

      Pages: 205-212

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Co-Activation of the secondary somatosensory and auditory cortices facilitates freqency discrimination of vibrotactile stimuli2007

    • Author(s)
      Iguchi Y, Hoshi Y, Nemoto M, Taira M, Hashimoto I
    • Journal Title

      Neuroscience 148

      Pages: 461-472

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cortical plasticity for language processing in the human brain2007

    • Author(s)
      Sakai KL, Muto M.
    • Journal Title

      Cognit Sci 1

      Pages: 211-225

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of task demands on the responses of color-selective neurons in the inferior temporal cortex.2007

    • Author(s)
      Koida, K., Komatsu, H.
    • Journal Title

      Nat. Neurosci. 10・1

      Pages: 108-116

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Latency of vestibular responses of pursuit neurons in the caudal frontal eye fields to whole body rotation.2007

    • Author(s)
      Akao, T., Saito, H., Fukushima, J., Kurkin, S., Fukushima, K.
    • Journal Title

      Exp. Brain Res. 177・3

      Pages: 400-410

    • NAID

      120000965344

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Activity in the lateral prefrontal cortex reflects multiple steps of future events in action plans.2006

    • Author(s)
      *Mushiake, H., Saito, N., Sakamoto, K., Itoyama, Y., Tanji, J.
    • Journal Title

      Neuron 50

      Pages: 631-641

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] High density presynaptic transporters are required for glutamate removal from the first visual synapse.2006

    • Author(s)
      Hasegawa, J., Obara, T., Tanaka, K., Tachibana, M.
    • Journal Title

      Neuron 50

      Pages: 63-74

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inactivation of the central thalamus delays self-timed saccades.2006

    • Author(s)
      *Tanaka, M.
    • Journal Title

      Nature Neurosci 9

      Pages: 20-22

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct and fast detection of neuronal activation in the human brain with diffusion MRI.2006

    • Author(s)
      Le Bihan, D., Urayama, S., Aso, T., Hanakawa, T., Fukuyama, H.
    • Journal Title

      Proc Natl Acad Sci USA 103

      Pages: 8263-8268

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.2006

    • Author(s)
      Takayasu, S., Sakurai, T., Iwasaki, S., Teranishi, H., Yamanaka, A., Williams, SC., Iguchi, H., Kawasawa, YI., Ikeda, Y., Sakakibara, I., Ohno, K., Ioka, RX., Murakami, S., Dohmae, N., Xie, J., Suda, T., Motoike, T., Ohuchi, T., Yanagisawa, M., Sakai, J.
    • Journal Title

      Proc Natl Acad Sci USA 103(19)

      Pages: 7438-7443

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Navigation-associated medial parietal neurons in monkeys.2006

    • Author(s)
      Sato N., Sakata H., Tanaka Y., Taira M.
    • Journal Title

      Proc Natl Acad Sci 103

      Pages: 17001-17006

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reward association affects neuronal responses to visual stimuli in macaque TE and perirhinal cortices.2006

    • Author(s)
      Mogami, T., Tanaka, K.
    • Journal Title

      J. Neurosci. 26・25

      Pages: 6761-6770

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Neural correlates of internal model loading.2006

    • Author(s)
      Bursztyn, L.C.D., Ganesh, G., Imamizu, H., Kawato, M., Flanagan, R.
    • Journal Title

      Curr.Biol. 16・24

      Pages: 2440-2445

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Navigation-associated medial parietal neurons in monkeys.2006

    • Author(s)
      Sato, N., Sakata, H., Tanaka, Y., Taira, M.
    • Journal Title

      P.N.A.S. 103・45

      Pages: 17001-17006

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cortical hemoglobin-concentration changes under the coil induced by single-pulse TMS in humans : A simultaneous recording with near-infrared spectroscopy.2006

    • Author(s)
      Mochizuki, H., Ugawa, Y., Terao, Y., Sakai, K.L.
    • Journal Title

      Exp. Brain Res. 169・3

      Pages: 302-310

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Representation of action-specific reward values in the striatum.2005

    • Author(s)
      *Samejima, K., Ueda, Y., Doya, K., Kimura, M.
    • Journal Title

      Science 310

      Pages: 1337-1340

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Complementary process to response bias in the centromedian nucleus of the thalamus.2005

    • Author(s)
      Minamimoto, T., Hori, Y., Kimura, M.
    • Journal Title

      Science 308

      Pages: 1798-1801

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Input of Orexin/Hypocretin Neurons Revealed by a Genetically Encoded Tracer in Mice.2005

    • Author(s)
      Sakurai, T., Nagata, R., Yamanaka, A., Kawamura, H., Tsujino, N., Muraki, Y., Kageyama, H., Kunita, S., Takahashi, S., Goto, K., Koyama, Y., Shioda, S., Yanagisawa, M.
    • Journal Title

      Neuron 46(2)

      Pages: 297-308

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] View-invariant object recognition without experience of object rotations.2005

    • Author(s)
      Wang, G., Obama, S., Yamashita, W., Sugihara, T., Tanaka, K.
    • Journal Title

      Nature Neurosci 8

      Pages: 1568-1575

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synchronized retinal oscillations encode essential information for escape behavior in frogs.2005

    • Author(s)
      Ishikane, H., Gangi, M., Honda, S., Tachibana, M.
    • Journal Title

      Nature Neurosci 8

      Pages: 1087-1095

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Representation of action-specific reward values in the striatum.2005

    • Author(s)
      Samejima K, Ueda Y, Doya K, Kimura M.
    • Journal Title

      Science 310・5752

      Pages: 1337-1340

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Neural responses in the macaque V1 to bar stimuli with various lengths presented on the blind spot.2005

    • Author(s)
      Matsumoto M, Komatsu H.
    • Journal Title

      J Neurophysiol 93・5

      Pages: 2374-2387

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Prior experience of rotation is not required for recognizing objects seen from different angles.2005

    • Author(s)
      Wang G, Obama S, Yamashita W, Sugihara T, Tanaka K.
    • Journal Title

      Nat Neurosci 8・12

      Pages: 1768-1775

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Discharge characteristics of pursuit neurons in MST during vergence eye movements.2005

    • Author(s)
      Akao T, Mustari MJ, Fukushima J, Kurkin S, Fukushima K.
    • Journal Title

      J Neurophysiol 93・5

      Pages: 2415-2434

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Insoitol, 1, 4, 5-trisphosphate-dependent Ca2+ threshold dynamics detect spike timing in cerebellar Purkinje Cells.2005

    • Author(s)
      Doi T, Kuroda S, Michikawa T, Kawato M.
    • Journal Title

      J Neurosci 25・4

      Pages: 950-961

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Information processing of geometrical features of a surface based on binocular disparity cues : an fMRI study.2005

    • Author(s)
      Naganuma T, Nose I, Inoue K, Takemoto A, Taira M.
    • Journal Title

      Neurosci Res 51・2

      Pages: 147-155

    • NAID

      10015450776

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Language Acquisition and Brain Development2005

    • Author(s)
      Sakai KL.
    • Journal Title

      Science 310・5749

      Pages: 815-819

    • NAID

      40019429312

    • Related Report
      2005 Annual Research Report
  • [Journal Article] シンポジウム「統合的脳研究への新展開-新特定領域研究の発足にあたって-」の開催(「統合脳」5領域主催)

    • Journal Title

      開催年月日・場所:平成16年10月2日・東京

    • Related Report
      2004 Annual Research Report
  • [Presentation] Value signals for decision and action selection in the basal ganglia2011

    • Author(s)
      Kimura M.
    • Organizer
      Janelia Conference Neural Circuits of Decision-Making
    • Place of Presentation
      Janelia Farm Research Campus, VA, USA
    • Year and Date
      2011-03-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] Differential encoding of reward value and its prediction error by dopamine neurons located in ventromedial and dorsolateral parts of the midbrain2010

    • Author(s)
      Enomoto K.
    • Organizer
      The 40th annual meeting of Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Top-down signal from the frontal cortex regulates social value orientation.2010

    • Author(s)
      Haruno M.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸国際会議場,兵庫県
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Dopamine neurons in ventromedial and dorsolateral part of the midbrain differentially encode reward value and its error.2010

    • Author(s)
      Enomoto K.
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸国際会議場,兵庫県
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Involvement of the basal ganglia in valuation and selection of actions.2009

    • Author(s)
      Kimura M, Yamada H, Enomoto K, Matsumoto N, Hori Y, Ueda Y., Yamanaka K.(研究代表者)
    • Organizer
      The 36^<th> Congress of the International Union of Physiological Sciences(IUPS2009)(シンポジウム特別講演)
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-07-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Adaptation of reward-based free-choices is impaired by D1 but not D 2 dopamine receptor antagonist in the striatum.2008

    • Author(s)
      Ueda Y, Samejima K, Yamanaka K, Doya K, Kimura M.
    • Organizer
      The 38th annual meeting of Society for Neuroscience.
    • Place of Presentation
      Washington DC, USA.
    • Year and Date
      2008-11-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] Shogi pattern recognition in professional players2008

    • Author(s)
      Wan X, Nakatani H, Ueno K, Asamizuya T, Cheng K, Tanaka, K.
    • Organizer
      The 38th annual meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Anatomical dissociation of CIP and LIP in the macaque intraparietal cortex.2008

    • Author(s)
      Katsuyama N, Yamashita A, Sato N, Usui N, Taira M
    • Organizer
      The 38th annual meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Towards Manipulative Neuroscience based on Brain -Network- Interface.2008

    • Author(s)
      Kawato M.
    • Organizer
      Neuroinformatics 2008
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2008-09-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] Neural processing of colour in higher cortical areas.2008

    • Author(s)
      Komatsu H.
    • Organizer
      5th Asian-Pacific Conference on Vision
    • Place of Presentation
      Brisbane, Australia Fragm
    • Year and Date
      2008-07-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Towards the neuroscience of language2008

    • Author(s)
      酒井邦嘉
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Visual Motion-Memory and Predictive Pursuit : Comparison of SEF and FEE.2008

    • Author(s)
      Fukushima K.
    • Organizer
      A Festschrift in Honor of Albert F Fuchs. Neural mechanisms of ocular and vestibular function
    • Place of Presentation
      Medford, Oregon, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] 価値判断と意志決定に関わる大脳基底核の神経信号2007

    • Author(s)
      木村 實
    • Organizer
      第30回日本分子生物学年会・第80回日本生化学会大会合同大会(BMB2007)
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] Uniquely Human Language Processing2007

    • Author(s)
      Sakai KL
    • Organizer
      The 10th Annual Symposium of Japanese-American Frontiers of Science(JAFoS)Symposium
    • Place of Presentation
      神奈川県三浦郡
    • Year and Date
      2007-12-03
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cerebellar long term depression as a supervised learning rule with all or nothing character at each synapse2007

    • Author(s)
      Kawato M
    • Organizer
      14th International Conference on Neural Information Processing(ICONIP2007)
    • Place of Presentation
      北九州サイエンスリサーチパーク
    • Year and Date
      2007-11-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] Activation of ventromedial parietal cortex during apparent motion perception induced by cast shadows2007

    • Author(s)
      Katsuyama N, Usui N, Nose I, Taira M
    • Organizer
      37th Society for Neuroscience Meeting
    • Place of Presentation
      San Diego,U.S.A.
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Color-related subregions in the monkey inferior temporal cortex revealed by functional MRI2007

    • Author(s)
      Harada T, Goda N, Ogawa T, Ito M, Toyoda H, Sadato N, Komatsu H
    • Organizer
      37th Society for Neuroscience Meeting
    • Place of Presentation
      San Diego,U.S.A.
    • Year and Date
      2007-11-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] Integration of features along the dorsal and ventral visual pathways to represent biologically meaningful information2007

    • Author(s)
      Tanaka K.
    • Organizer
      7th IBRO World Congress of Neuroscience
    • Place of Presentation
      Melbourne,Australia
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Discharge of pursuit neurons in the caudal part of the frontal eye fields during head-free pursuit2007

    • Author(s)
      Fukushima K
    • Organizer
      Gordon Research Conference.Oculomotor System Biology
    • Place of Presentation
      Bates College,Lewiston,ME,USA
    • Related Report
      2007 Annual Research Report
  • [Book] Neuroeconomics : Decision Making and the Brain2009

    • Author(s)
      Doya K. & Kimura M.
    • Total Pages
      538
    • Publisher
      Academic Press
    • Related Report
      2008 Annual Research Report
  • [Book] Systems Biology2009

    • Author(s)
      Ogasawara H. & Kawato M.
    • Publisher
      Springer
    • Related Report
      2008 Annual Research Report
  • [Book] 脳の情報処理2008

    • Author(s)
      小松英彦
    • Publisher
      情報処理学会
    • Related Report
      2008 Annual Research Report
  • [Book] Using Eye Movements as an Experimental Probe of Brain Function. A Symposium in Honor of Jean Buttner-Ennever.Prog Brain Res vol 171.2008

    • Author(s)
      Fukushima J, Asaka T. & Fukushima K.
    • Publisher
      Elsevier Science Ltd.
    • Related Report
      2008 Annual Research Report
  • [Book] 哲学の歴史別巻2008

    • Author(s)
      酒井邦嘉
    • Publisher
      中央公論新社
    • Related Report
      2008 Annual Research Report
  • [Book] The Senses:A Comprehensive Reference, Vol 2-Vision II2008

    • Author(s)
      Komatsu H
    • Publisher
      Academic Press
    • Related Report
      2007 Annual Research Report
  • [Book] Using Eye Movements as an Experimental Probe of Brain Function, edited by R John Leigh and C Kennard.Prog Brain Res vol.1712008

    • Author(s)
      Fukushima K, Akao T, Shichinohe N Nitta T, Kurkin S, Fukushima J.
    • Publisher
      Elsevier
    • Related Report
      2007 Annual Research Report
  • [Book] Attention and Performance, XXII2008

    • Author(s)
      Haggard P, Rossetti Y, Kawato M
    • Publisher
      Oxford University Press
    • Related Report
      2007 Annual Research Report
  • [Book] 生命システムをどう理解するか-細胞から脳機能・進化にせまる融合科学2007

    • Author(s)
      酒井 邦嘉
    • Publisher
      共立出版
    • Related Report
      2007 Annual Research Report
  • [Book] Recent Breakthroughs in Basal Ganglia Research. (Motivational Signals of Dopamine Neurons. pp.81-90)2006

    • Author(s)
      Kimura, M., Satoh, T., Sato, T., Enomoto, K., Matsumoto, N.
    • Total Pages
      450
    • Publisher
      Nova Science Publishers, New York. (Ed. By Bezard, E.)
    • Related Report
      2006 Annual Research Report
  • [Patent(Industrial Property Rights)] 画像特徴抽出装置、画像特徴抽出方法、画像認識装置、及び画像認識方法2009

    • Inventor(s)
      大澤五住、新井稔也、眞田尚久
    • Industrial Property Rights Holder
      大阪大学
    • Filing Date
      2009-10-26
    • Acquisition Date
      2009-10-26
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 内因性オピオイドペプチド産生ニューロの可視化に利用可能なトランスジェニック非ヒト動物およびその利用2005

    • Inventor(s)
      金子武嗣
    • Industrial Property Rights Holder
      独立行政法人科学技術振興機構
    • Filing Date
      2005-12-14
    • Acquisition Date
      2005-12-14
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] リハビリ装置2005

    • Inventor(s)
      神作憲司、松田圭司
    • Industrial Property Rights Holder
      自然科学研究機構、吉川弘之
    • Filing Date
      2005-07-15
    • Acquisition Date
      2005-07-15
    • Related Report
      2009 Final Research Report

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Published: 2004-04-01   Modified: 2018-08-07  

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