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生体機能分子の創製の研究統括

Research Project

Project/Area Number 16073101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionThe University of Tokyo

Principal Investigator

福山 透  The University of Tokyo, 大学院・薬学系研究科, 教授 (10272486)

Co-Investigator(Kenkyū-buntansha) 小林 資正  大阪大学, 大学院・薬学研究科, 教授 (40116033)
佐々木 誠  東北大学, 大学院・生命科学研究科, 教授 (80235267)
谷野 圭持  北海道大学, 大学院・理学研究院, 教授 (40217146)
菅 敏幸 (管 敏幸)  静岡県立大学, 薬学部, 教授 (10221904)
Project Period (FY) 2004 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥227,700,000 (Direct Cost: ¥227,700,000)
Fiscal Year 2008: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2007: ¥27,000,000 (Direct Cost: ¥27,000,000)
Fiscal Year 2006: ¥27,000,000 (Direct Cost: ¥27,000,000)
Fiscal Year 2005: ¥27,000,000 (Direct Cost: ¥27,000,000)
Fiscal Year 2004: ¥143,700,000 (Direct Cost: ¥143,700,000)
Keywords全合成 / 生体機能分子 / 天然物 / 生理活性 / 機能解明 / 生理活性物質 / 単離 / 構造決定 / 新規反応開発 / 独創的合成 / 革新的合成反応 / 分子プローブ / 生命現象の解明 / 共同研究体制 / 活性天然物質の探索 / 生物活性評価系の構築 / 稀少活性天然物質 / 各種標識分子 / プローブ / 有機合成化学 / 生物有機化学 / 大型機器
Research Abstract

平成20年6月に、取りまとめの公開シンポジウムをタワーホール船堀(東京)にて実施した。このとき代表的な研究成果を中心に公開し、成果を社会に対して発信した。これらの研究成果は、生命現象の化学的解明に飛躍的な進展や新戦略による創薬にも直結するため、製薬に代表される産業界においても有用であり、公開シンポジウムでは企業の研究者も幅広く参加した。また、本特定領域研究では、各研究項目の計画研究班員と公募班員の間での緊密な共同研究体制を構築することを重要課題として掲げた。これまで、公開シンポジウムやHPにより研究者の相互の理解を深め、有機的連携と緊密な共同研究体制を構築した。現在までに、30組以上の領域内共同研究が進行中であり、成果があがりつつある。
また、最終報告も平成21年3月に作成した。この最終報告書にはおのずと解決された問題と、さらに解決されなかった問題(既存の学術誌等には投稿できない)が例示されることとなるため、この方面の研究者にとって研究課題が容易に見つけ出せるバイブル的な存在になるように留意し整理した。また、班員、研究協力者、班友の業績を中心としたテキスト「天然物の全合成 : 2001〜2008」の編纂を行った。現在最終校正の段階にあり、平成21年中に発売可能な状態にある。本特定領域ではすでに50を超える生理活性天然物(生体機能分子)の全合成を達成している。それらを網羅する本書は、インパクトが大きい。

Report

(5 results)
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (93 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (51 results) (of which Peer Reviewed: 21 results) Presentation (35 results) Book (3 results) Remarks (2 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Total Synthesis of (+)-Yatakemycin2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Chem. Asian J. 3

      Pages: 296-309

    • Related Report
      2008 Annual Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total Synthesis of (-)-Serotobenine2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      J. Am. Chem. Soc 130

      Pages: 16854-16855

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Mild Inter and Intramolecurar Amination of Aryl Halides with a Combination of CuI and CsOAc2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Tetrahedron 64

      Pages: 11230-11236

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mild Debenzylation of Aryl Benzyl Ether with BCI3 in the Presence of Pentamethylbenzene as a Non-Lewis-Basic Cation Scavenger2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Synlett

      Pages: 1977-1980

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthetic Studies on (+)Manzamine A : Stereoselective Synthesis of the Tetracyclic Core Framework2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett 10

      Pages: 3251-3253

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] (1-Nosyl-5-nitroindol-3-yl)methyl Ester : A Noyel Protective Group for Carboxylic Acids2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett 10

      Pages: 2601-2604

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Eudistomin C and E : Improved Preparation of the Indole Unit2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett 10

      Pages: 2369-2372

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Simple Chiral Template for the Synthesis of Fuctionalized α-Arylglycine Derivatives2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Heterocycles 76

      Pages: 747-757

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] O-TBS-N-tosylhydroxylamine : A Reagent for Facile Conversion of Alcohols to Oximes2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 10

      Pages: 2259-2261

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total Synthesis of (-)-Kainic Acid via Intramolecular Michael Addition : A SecondGeneration Route2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett 10

      Pages: 1711-1714

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthetic Studies on Altemicidin : Stereocontrolled Construction of the Core Framework2008

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett 10

      Pages: 169-171

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stereocontrolled Total Synthesis of (-)-Kainic Acid2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 9

      Pages: 1635-1638

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Convenient Synthesis of Photoaffinity Probes and Evaluation of Their Labeling Abilities2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 9

      Pages: 2055-2058

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Novel Indole Synthesis via Conjugate Addition of Pyrrolidine to o-Nitrophenylacetylenes2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Heterocycles 72

      Pages: 191-197

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Divergent Synthesis of Multifunctional Molecular Probes Enabled Elucidation of the Enzyme Specificity of Dipeptidic γ-Secretase Inhibitors on Presenilin-Type Aspartic Proteases2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      ACS Chemical Biology 2

      Pages: 408-418

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Practical Synthesis of (-)-Oseltamivir2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Angew. Chem. Int. Ed. 46

      Pages: 5734-5736

    • NAID

      130007969712

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] N,N'-Ditosylhydrazine: A Convenient Reagent for Facile Synthesis of Diazoacetates2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 9

      Pages: 3195-3197

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design and synthesis of thiazoline-thiazole hybrid macrocycles possessing strong binding affinity to Pb2+ and Cd2+2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Chem. Commun.

      Pages: 3444-3446

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of (+)-Vinblastine and Its Analogues2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 9

      Pages: 4737-4740

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Versatile Synthesis of α-Amino Acid Derivatives via the Ugi Four-Component Condensation with a Novel Convertible Isonitrile2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Heterocycles 73

      Pages: 403-417

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthetic Studies on Haplophytine: Protective Group Controlled Rearrangement2007

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Synlett

      Pages: 3137-3140

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total Synthesis of (±)-Morphine2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org. Lett. 8

      Pages: 5311-5313

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Total Synthesis of (+)-Yatakemycin2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      J. Am. Chem. Soc. 128

      Pages: 7136-7137

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Novel γ-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Bioorg. Med. Chem. Lett. 16

      Pages: 3813-3816

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A Novel Synthesis of Bicyclo[3. 3. 0]octane Ring System via a Desymmetric C-H Insertion Reaction2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Synlett

      Pages: 1583-1585

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Synthesis of biotinylated photoaffinity probes based on arylsulfonamide γ-secretase inhibitors2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Bioorg. Med. Chem. Lett. 16

      Pages: 4148-4189

    • Related Report
      2006 Annual Research Report
  • [Journal Article] C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT2006

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      J. Biol. Chem. 281

      Pages: 14670-14676

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Stereo controlled Total Synthesis of(-)-Eudistomin C2005

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      J.Am.Chem.Soc. 127

      Pages: 15038-15038

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Synthesis of Tetrahydro- -carbolines via Radical Cyclization of 2-Alkenylthioanilides2005

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Heterocycle 66

      Pages: 241-241

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Stereocontrolled Total Synthesis of(-)-Kainic Acid.Regio-and Stereoselective Lithiation of Pyrrolidine Ring with the(+)-Sparteine Surrogate2005

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Org.Lett. 7

      Pages: 4337-4337

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Synthetic Studies on(-)-Lemonomycin : Stereocontrolled Construction of the 3,8-Diazabicyclo[3.2.1]Skeleton2005

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Synlett

      Pages: 523-523

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 天然物の全合成と反応開発2005

    • Author(s)
      福山 透
    • Journal Title

      ファルマシア 41巻4号

      Pages: 304-304

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Synthetic Studies on(-)-Lemollomycin : Stereocontrolled Construction of the 3,8-Diazabicyclo[3.2.1]Skeleton2005

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Chem.Commun.

      Pages: 394-394

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Total Synthesis of (-)-Strychnine.2004

    • Author(s)
      Yosuke Kaburagi
    • Journal Title

      J.Am.Chem.Soc. 126

      Pages: 10246-10247

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Synthetic Studies on (+)-Naphthyridinomycin : Stereoselective Synthesis of the Tetracyclic Core Framework.2004

    • Author(s)
      Kazuki Mori
    • Journal Title

      Org.Lett. 6

      Pages: 3095-3097

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Stereocontrolled Total Synthesis of Potent Immunosuppressant FR9014832004

    • Author(s)
      Toshiyuki Kan
    • Journal Title

      Org.Lett. 6

      Pages: 2729-2731

    • Related Report
      2004 Annual Research Report
  • [Journal Article] A Versatile Synthesis of -Amino Acid Derivatives Via the Ugi Four-Component Condensation with a Novel Convertible Isonitrile2004

    • Author(s)
      Kentaro Rikimaru
    • Journal Title

      Synlett

      Pages: 41-43

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Enantioselective Total Synthesis of FR9004822004

    • Author(s)
      Masashi Suzuki
    • Journal Title

      J.Org.Chem. 69

      Pages: 2831-2843

    • Related Report
      2004 Annual Research Report
  • [Journal Article] New Odorless Protocols for the Synthesis of Aldehydes and Ketones from Thiol Esters2004

    • Author(s)
      Tohru Miyazaki
    • Journal Title

      Synlett

      Pages: 477-480

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Ns Strategies : A Highly Versatile Synthetic Method for Amines2004

    • Author(s)
      Toshiyuki Kan
    • Journal Title

      Chem.Commun

      Pages: 353-354

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Parallel Synthesis of DAPT Derivatives and Their Secretase Inhibitory Activity2004

    • Author(s)
      Toshiyuki Kan
    • Journal Title

      Bioorg.Med.Chem.Lett 14

      Pages: 1983-1986

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Highly Efficient Synthesis of Medium-Sized Lactams Via Intramolecular Staudinger-Aza-Wittig Reaction of omega-Azide Pentaphenyl Ester : Synthesis and Biological Evaluation of LY411575 Analogues2004

    • Author(s)
      Haruhiko Fuwa
    • Journal Title

      Tetrahedron Lett 45

      Pages: 2323-2327

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Stereoselective Nucleophilic Addition Reaction with a New Chiral Template and Its Application to Synthesis of Optically Active -Aryglycine Derivatives2004

    • Author(s)
      Sigemitsu Tohma
    • Journal Title

      Synthesis

      Pages: 909-917

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 4-(t-Butyldimethylsilyloxy)benzylidene Acetal : A Novel Benzylidene-type Protecting Group for 1,2-Diols2004

    • Author(s)
      Yosuke Kaburagi
    • Journal Title

      Tetrahedron Lett 45

      Pages: 3817-3821

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Stereocontrolled Total Synthesis of (+)-Vincristine2004

    • Author(s)
      Takeshi Kuboyama
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 11966-11970

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Total Synthesis of (-)-Ephedradine A (Orantine) : An Efficient Construction of Optically Active Dihydrobenzofuran-ring via C-H Insertion Reaction2004

    • Author(s)
      Wataru Kurosawa
    • Journal Title

      Tetrahedron 60

      Pages: 9615-9628

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Synthetic Studies on (-)-Lemonomycin : Stereocontrolled Construction of the 3,8-Diazabicyclo[3.2.1] Skeleton2004

    • Author(s)
      Kentaro Rikimaru
    • Journal Title

      Chem.Commun

      Pages: 394-396

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Palladium-Mediated Synthesis of Aldehydes and Ketones from Thiol Esters.2004

    • Author(s)
      Tohru Fukuyama
    • Journal Title

      Aldrichimica Acta 37

      Pages: 87-96

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 世界をリードする日本の化学、実用的な有機合成を目指す-ビンブラスチン全合成の考え方-2004

    • Author(s)
      福山 透
    • Journal Title

      現代化学 7

      Pages: 38-43

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 注目の論文「(-)-テトロドトキシンの全合成:古くから知られる天然物の新しい全合成」2004

    • Author(s)
      菅 敏幸
    • Journal Title

      化学 8

      Pages: 66-67

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 提案「今こそ、天然物の全合成!」2004

    • Author(s)
      菅 敏幸
    • Journal Title

      化学 11

      Pages: 50-52

    • Related Report
      2004 Annual Research Report
  • [Presentation] 海洋天然物ユーディストミンの新規類縁体合成2008

    • Author(s)
      福山透
    • Organizer
      第56回有機合成化学協会関東支部シンポジウム(新潟シンポジウム)
    • Place of Presentation
      新潟
    • Year and Date
      2008-11-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] (-)-モルヒネの全合成研究2008

    • Author(s)
      福山透
    • Organizer
      第27回メデイシナルケミストリーシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Huperzine Aの全合成2008

    • Author(s)
      福山透
    • Organizer
      第27回メデイシナルケミストリ-シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Anisatinの合成研究2008

    • Author(s)
      福山透
    • Organizer
      第94回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] (-)-モルヒネの全合成研究2008

    • Author(s)
      福山透
    • Organizer
      第34回反応と合成の進歩シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-11-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] キラルなプロパルギルアミンを用いた立体選択的アレン合成2008

    • Author(s)
      福山透
    • Organizer
      第52回日本薬学会関東支部大会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] HuperzineAの全合成2008

    • Author(s)
      福山透
    • Organizer
      第50回天然有機化合物討論会
    • Place of Presentation
      福岡
    • Year and Date
      2008-10-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] スルホニル基の特性を活用した新規ジアゾ酢酸エステル及びオキシム合成法の開発2008

    • Author(s)
      福山透
    • Organizer
      第93回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-06-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] インドールの特性を利用した新規カルボン酸保護基の開発2008

    • Author(s)
      福山透
    • Organizer
      第55回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2008-05-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Chartelline Aの合成研究2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 天然物合成中間体ライブラリーからのγセクレターゼ阻害剤の探索2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] キラルなプロパルギルアミンを用いた立体選択的アレン合成2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] spirotryprostatin Aの合成研究2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] Synthetic Studies on Manzamine A2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] トリプロスタチン類の合成2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 海洋天然物ユーディストミンの新規類縁体合成2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] インドールの特性を利用した新規力ルボン酸保護基の開発2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] (-)-Huperzine Aの合成研究2008

    • Author(s)
      福山 透
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] プラキニジン類の全合成研究2008

    • Author(s)
      福山 透
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] (-)-メルシカルピンの全合成研究2008

    • Author(s)
      福山 透
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 穏和な条件で切断可能なリンカーユニットの開発とフォトアフィニティープローブへの応用2008

    • Author(s)
      福山 透
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] (-)-テトロドトキシンの合成研究2008

    • Author(s)
      福山 透
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] オセルタミビル誘導体の合成2008

    • Author(s)
      福山透
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] トリプロスタチン類の全合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第54回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      新潟
    • Year and Date
      2007-12-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 天然物合成中間体ライブラリーを用いた新規γーセクレターゼ阻害剤の探索研究2007

    • Author(s)
      福山 透
    • Organizer
      第26回メデイシナルケミストリーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-11-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Manzamine Aの合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第92回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-11-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] エクチナサイジン743の合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第33回反応と合成の進歩シンポジウム
    • Place of Presentation
      長崎
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] (+)-Lysergic acidの合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第37回複素環化学討論会
    • Place of Presentation
      長野
    • Year and Date
      2007-10-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] 穏和な条件で切断可能なリンカーユニットの開発とフォトアフィニティープローブへの応用2007

    • Author(s)
      福山 透
    • Organizer
      第51回薬学会関東支部大会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] (-)-Conophyllineの全合成2007

    • Author(s)
      福山 透
    • Organizer
      第49回天然有機化合物討論会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] スルホニル基の特性を活用した新規ジアゾ酢酸エステル及びオキシム合成法の開発2007

    • Author(s)
      福山 透
    • Organizer
      第24回有機合成化学セミナー
    • Place of Presentation
      淡路島
    • Year and Date
      2007-09-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] (-)-モルヒネの合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第91回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-06-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] (-)-Lemonomycinの合成研究2007

    • Author(s)
      福山 透
    • Organizer
      第5回次世代を担う有機化学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-05-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] スルホニル基の特性を活用した新規ジアゾ酢酸エステル及びオキシム合成法の開発2007

    • Author(s)
      福山 透
    • Organizer
      第53回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2007-05-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Eudistomin類の改良合成2007

    • Author(s)
      福山 透
    • Organizer
      第53回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2007-05-11
    • Related Report
      2007 Annual Research Report
  • [Book] インタラクティブ有機化学英語2007

    • Author(s)
      福山 透
    • Publisher
      有機合成化学協会
    • Related Report
      2006 Annual Research Report
  • [Book] 演習で学ぶ有機反応機構 大学院入試から最先端まで2005

    • Author(s)
      福山 透 他
    • Total Pages
      271
    • Publisher
      化学同人
    • Related Report
      2005 Annual Research Report
  • [Book] 化学系薬学 I.化学物質の性質と反応(日本薬学会編)2004

    • Author(s)
      徳山英利(分担執筆)
    • Total Pages
      353
    • Publisher
      東京化学同人
    • Related Report
      2004 Annual Research Report
  • [Remarks]

    • URL

      http://www.f.u-tokyo.ac.Jp/~fukuyama/index-j.htm

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://organic2.scl.hokudal.ac.JP/seitaikinou/

    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] モルヒネの製造方法2008

    • Inventor(s)
      福山透
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2008-161165
    • Filing Date
      2008-06-20
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] イソキヌクリジン誘導体およびこれを利用した1-シクロヘキセン-1-カルボン酸誘導体の製法2006

    • Inventor(s)
      福山 透
    • Industrial Property Number
      2006-206987
    • Filing Date
      2006-07-28
    • Related Report
      2006 Annual Research Report

URL: 

Published: 2004-04-01   Modified: 2018-03-28  

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