Mechanisms of brain sex differentiation induced by neurosteroids

• Project/Area Number: 16086206
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Waseda University (2006-2008); Hiroshima University (2004-2005)
• Principal Investigator: TSUTSUI Kazuyoshi Waseda University, 教育・総合科学学術院, 教授 (20163842)
• Co-Investigator(Kenkyū-buntansha): SAKAGUCHI Hironobu 獨協医科大学, 医学部, 准教授 (30162291) ; OKANOYA Kazuo 理化学研究所, 脳科学総合研究センター, 生物言語研究チームリーダー (30211121) ; UKENA Kazuyishi 広島大学, 大学院・総合科学研究科, 准教授 (10304370)
• Project Period (FY): 2004 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥84,000,000 (Direct Cost: ¥84,000,000); Fiscal Year 2008: ¥16,800,000 (Direct Cost: ¥16,800,000); Fiscal Year 2007: ¥16,800,000 (Direct Cost: ¥16,800,000); Fiscal Year 2006: ¥16,800,000 (Direct Cost: ¥16,800,000); Fiscal Year 2005: ¥16,800,000 (Direct Cost: ¥16,800,000); Fiscal Year 2004: ¥16,800,000 (Direct Cost: ¥16,800,000)
• Keywords: 脳の性分化 / 性的二型核 / ニューロステロイド / アポトーシス抑制因子 / Ad4BP / SF-1 / 鳥類 / エストラジオール / 7a-ヒドロキシプレグネノロン / P450 / cDNAマイクロアレイ / 7α-ヒドロキシプレグネノロン / 脳の性差 / CYP7b

Research Abstract

脳の性分化機構は未解明の重要課題である。本研究は、脳の自立的性分化機構の解明を目的として、脳の構造と行動に最も典型的な性差を示す鳥類のウズラを用い、脳が合成するニューロステロイドに着目して、ニューロステロイドによる脳の性分化誘導作用を解析した。その結果、脳の性分化に重要となる感受性期の間脳では、転写調節因子であるAd4BP/SF-1がニューロステロイド合成酵素の発現に性差を導くことでニューロステロイド合成に性差が生じて脳の性分化が誘導されることが見いだされた。

Research Products

• [Journal Article] Molecular evolution of multiple forms of kisspeptins and GPR54 receptors in vertebrates (2009)
  • Author(s): Y. R. Lee(筆頭著者), K. Tsutsui(最終著者),et al(著者13名)
  • Journal Title: Endocrinology doi:10.1210/en Pages: 2008-1679
  • Peer Reviewed
• [Journal Article] Diurnal changes in the synthesis of 7α-hydroxypregnenolone stimulating locomotor activity in newts (2009)
  • Author(s): T. Koyama(筆頭著者), K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: Ann. N. Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Seasonal changes in the synthesis of 7α-hydroxypregnenolone stimulating locomotor activity in newts (2009)
  • Author(s): S. Haraguchi(筆頭著者), K. Tsutsui(最終著者),et al(著者4名)
  • Journal Title: 7α-hydroxypregnenolone stimulating locomotor activity in newts (in press)
  • Peer Reviewed
• [Journal Article] Review : Neurosteroid biosynthesis : enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides (2009)
  • Author(s): J. L. DoRego(筆頭著者), K. Tsutsui(8番目), et al(著者9名)
  • Journal Title: Front. Neuroendocrinol. (in press)
  • Peer Reviewed
• [Journal Article] Review : Discovery of a novel avian neurosteroid, 7・-hydroxypregnenolone, and its role in the regulation of the diurnal rhythm of locomotor activity in Japanese quail (2009)
  • Author(s): K. Tsutsui(筆頭著者), et al(著者7名)
  • Journal Title: Gen. Comp. Endocrinol. (in press)
  • Peer Reviewed
• [Journal Article] Review : A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH) : Biosynthesis, mode of action and functional significance (2009)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: Prog. Neurobiol. 88 Pages: 76-88
  • Peer Reviewed
• [Journal Article] Review : Neurosteroid biosynthesis and action in the Purkinje cell (2009)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: cell. J. Exp. Neurosci. 2 Pages: 1-12
  • Peer Reviewed
• [Journal Article] A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH) in birds : discovery, progress and prospect (review) (2009)
  • Author(s): K. Tsutsui(筆頭著者), K. Ukena(7番目), et al(著者10名)
  • Journal Title: J. Neuroendocrinol. 21 Pages: 271-275
  • Peer Reviewed
• [Journal Article] Identification, biosynthesis and function of 7・-hydroxypregnenolone, a new key neurosteroid controlling locomotor activity, in non-mammals (review) (2009)
  • Author(s): K. Tsutsui(筆頭著者), et al(著者9名)
  • Journal Title: Ann. N.Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Molecular evolution of multiple forms of kisspeptins and GPR54 receptors in vertebrates (2009)
  • Author(s): Y. R. Lee, et.al.
  • Journal Title: Endocrinology (in press)
  • Peer Reviewed
• [Journal Article] Diurnal changes in the synthesis of 7alpha-hydroxypregnenolone stimulating locomotor activity in newts (2009)
  • Author(s): T. Koyama, et.al.
  • Journal Title: Ann. N.Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Seasonal changes in the synthesis of 7alpha-hydroxypregnenolone stimulating locomotor activity in newts. (2009)
  • Author(s): S. Haraguchi, et.al.
  • Journal Title: Ann. N.Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Review : Neurosteroid biosynthesis : enzymatic pathways and neuroendocrine regulation by neurotransmitte rs and neuropeptides (2009)
  • Author(s): J. L. Do Rego, et.al.
  • Journal Title: Front. Neuroendocrinol. (in press)
  • Peer Reviewed
• [Journal Article] Review : Discovery of a novel avian neurosteroid, 7alpha-hydroxypregnenolone, and its role in the regul ation of the diurnal rhythm of locomotor activity in Japanese quail (2009)
  • Author(s): K. Tsutsui, et.al.
  • Journal Title: Gen. Comp. Endocrinol. (in press)
  • Peer Reviewed
• [Journal Article] Review : Proximate and ultimate mechanisms driving circadian control of neuroendocrine function : Lesson s from the young and old (2009)
  • Author(s): W. P. Williams III, et.al.
  • Journal Title: Integr. Comp. Biol. (in press)
  • Peer Reviewed
• [Journal Article] Review : Gonadotropin-inhibitory hormone (GnIH) and its homologous peptides in vertebrates : discovery, mode of action and functional significance (2009)
  • Author(s): K. Tsutsui
  • Journal Title: Prog. Neurobiol. (in press)
  • Peer Reviewed
• [Journal Article] A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH) in birds : disc overy, progress and prospect (review) (2009)
  • Author(s): K. Tsutsui, et.al.
  • Journal Title: J. Neuroendocrinol 21 Pages: 271-275
  • Peer Reviewed
• [Journal Article] GnlH : A Multifunctional Neuropeptide (2009)
  • Author(s): G. E. Bentley, et.al.
  • Journal Title: J. Neuroendocrinol 21(review) Pages: 276-281
  • Peer Reviewed
• [Journal Article] Octopus GnRH (oct-GnRH), a multifunctional peptide in the endocrine and nervous systems of the cephalo pod (review) (2009)
  • Author(s): H. Minakata, et.al.
  • Journal Title: J. Neuroendocrinol 21 Pages: 322-326
  • Peer Reviewed
• [Journal Article] Evolutionary origin and divergence of GnIH and its homologous peptides (review) (2009)
  • Author(s): K. Tsutsui and T. Osugi
  • Journal Title: Gen. Comp. Endocrinol 161 Pages: 30-33
  • Peer Reviewed
• [Journal Article] Identification, biosynthesis and function of 7alpha-hydroxypregnenolone, a new key neurosteroid contro lling locomotor activity, in non-mammals (review) (2009)
  • Author(s): K. Tsutsui, et.al.
  • Journal Title: Ann. N.Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Hormone-mediated reproductive behavior in the red-bellied newt (review) (2009)
  • Author(s): S. Kikuyama, et.al.
  • Journal Title: Ann. N.Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Steroid Biosynthesis within the frog brain : A model of neuroendocrine regulation (review) (2009)
  • Author(s): J. L. Do Rego, et.al.
  • Journal Title: Ann. N. Y. Acad. Sci. (in press)
  • Peer Reviewed
• [Journal Article] メラトニンとGnIHの光周性 (2009)
  • Author(s): 筒井和義
  • Journal Title: 光周性の分子生物学海老原・井澤編 (印刷中)
  • Peer Reviewed
• [Journal Article] メラトニンに関する最近の話題 : メラトニンとGnIH (2009)
  • Author(s): 筒井和義
  • Journal Title: 糖尿病・代謝・内分泌2009中外医学社 5 Pages: 190-195
  • Peer Reviewed
• [Journal Article] Alterations in RFamide-related peptide expression are coordinated with the preovulatory luteinizing hormone surge (2008)
  • Author(s): M. Gibson(筆頭著者), K. Tsutsui(最終著者),et al(著者7名)
  • Journal Title: Endocrinology 149 Pages: 4958-4969
  • Peer Reviewed
• [Journal Article] Potent action of RFRP-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion (2008)
  • Author(s): I. J. Clarke(筆頭著者), K. Tsutsui(12番目), et al(著者14名)
  • Journal Title: Endocrinology 149 Pages: 5811-5821
  • Peer Reviewed
• [Journal Article] Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats (2008)
  • Author(s): M. Murakami(筆頭著者), K. Tsutsui(最終著者), et al(著者7名)
  • Journal Title: J. Endocrinol 199 Pages: 105-112
  • Peer Reviewed
• [Journal Article] 7・-Hydroxypregnenolone mediates melatonin action underlying diurnal locomotor rhythms (2008)
  • Author(s): K. Tsutsui(筆頭著者), K. Inoue(2番目),et al(著者6名)
  • Journal Title: Jneuroscience 28 Pages: 2158-2167
  • Peer Reviewed
• [Journal Article] Melatonin stimulates the release of growth hormone and prolactin by inducing the expression of frog growth hormone-releasing peptide (fGRP) and its related peptide-2 (fGRP-RP-2) in the amphibian hypothalamus (2008)
  • Author(s): V. S. Chowdhury(筆頭著者), K. Tsutsui(最終著者),et al(著者6名)
  • Journal Title: Endocrinology 149 Pages: 962-970
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin- releasing hormone-I and -II neurons in European starling brain (2008)
  • Author(s): T. Ubuka(筆頭著者), K. Tsutsui(8番目) et al(著者9名)
  • Journal Title: Endocrinology 149 Pages: 268-278
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system (2008)
  • Author(s): G. Bentley(筆頭著者), K. Tsutsui(最終著者)et al(著者10名)
  • Journal Title: Gen. Comp. Endocrinol. 156 Pages: 34-43
  • NAID: 10020188345
  • Peer Reviewed
• [Journal Article] Auditory stimulation of reproductive function in male Rufous-winged Sparrows, Aimophila carpalis (2008)
  • Author(s): T. W. Small (筆頭著者), K. Tsutsui (5番目), et al(著者7名)
  • Journal Title: Horm. Behav. 53 Pages: 28-39
  • Peer Reviewed
• [Journal Article] Review: Neurosteroids in the Purkinje cell : Biosynthesis, mode of action and functional significance (2008)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: Mol. Neurobiol. 37 Pages: 116-125
  • Peer Reviewed
• [Journal Article] Review : Recent advances in reproductive neuroendocrinology : A role for the RFamide peptides in seasonal reproduction? (2008)
  • Author(s): T. J. Greives(筆頭著者), K. Tsutsui(4番目),et al(著者5名)
  • Journal Title: Proc. R. Soc. B 275 Pages: 1943-1951
  • Peer Reviewed
• [Journal Article] Review : Progesterone biosynthesis and action in the developing neuron (2008)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: Endocrinology 149 Pages: 2757-2761
  • Peer Reviewed
• [Journal Article] Review : Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum : A new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid (2008)
  • Author(s): H. Sakamoto(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: Cerebellum 7 Pages: 18-25
  • Peer Reviewed
• [Journal Article] Changes in GnRH I, bradykinin and their receptors and GnIH in the ovary of Calotes versicolor during reproductive cycle (2008)
  • Author(s): P. Singh, et.al.
  • Journal Title: Gen.Comp. Endocrinol. 159 Pages: 158-169
  • Peer Reviewed
• [Journal Article] Alterations in RFamide-related peptide expression are coordinated with the preovulatory luteinizing hormone surge (2008)
  • Author(s): E. M. Gibson, et.al.
  • Journal Title: Endocrinology 149 Pages: 4958-4969
  • Peer Reviewed
• [Journal Article] Potent action of RFRP-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion (2008)
  • Author(s): I. J. Clarke, et.al.
  • Journal Title: Endocrinology 149 Pages: 5811-5821
  • Peer Reviewed
• [Journal Article] Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats (2008)
  • Author(s): M. Murakami, et.al.
  • Journal Title: J. Endocrinol. 199 Pages: 105-112
  • Peer Reviewed
• [Journal Article] Immunohistochemical detection and biological activities of CYP17 (P450017) in the indifferent gonad of the frog Rana rugosa (2008)
  • Author(s): N. Sakurai, et.al.
  • Journal Title: J. Steroid Biochem. Mol. Biol. 112 Pages: 5-12
  • Peer Reviewed
• [Journal Article] 7alpha-Hydroxypregnenolone mediates melatonin action underlying diurnal locomotor rhythms (2008)
  • Author(s): K. Tsutsui, et.al.
  • Journal Title: J. Neuroscience 28 Pages: 2158-2167
  • Peer Reviewed
• [Journal Article] Melatonin stimulates the release of growth hormone and prolactin by inducing the expression of frog gr owth hormone-releasing peptide and its related peptide-2 in the amphibian hypothalamus (2008)
  • Author(s): V. S. Chowdhury, et.al.
  • Journal Title: Endocrinology 149 Pages: 962-970
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and-II neurons in European starling brain (2008)
  • Author(s): T. Ubuka, et.al.
  • Journal Title: Endocrinology 149 Pages: 268-278
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system (2008)
  • Author(s): G. Bentley, et.al.
  • Journal Title: Gen. Comp. Endocrinol 156 Pages: 34-43
  • Peer Reviewed
• [Journal Article] Photoperiod-independent hypothalamic regulation of luteinizing hormone secretion in a free-living Sonoran desert bird, the Rufous-winged Sparrow (Aimophila carpalis) (2008)
  • Author(s): T. W. Small, et.al.
  • Journal Title: Brain Behay. Evol. 71 Pages: 127-142
  • Peer Reviewed
• [Journal Article] Auditory stimulation of reproductive function in male Rufous-winged Sparrows, Aimophila carpalis (2008)
  • Author(s): T. W. Small, et.al.
  • Journal Title: Norm. Behay 53 Pages: 28-39
  • Peer Reviewed
• [Journal Article] The orexigenic effect of GnIH is mediate by central opioid receptors in chicks (2008)
  • Author(s): T. Tachibana, et.al.
  • Journal Title: Comp. Biochem. Physiol. A Mol. Integr. Physiol. 150 Pages: 21-25
  • Peer Reviewed
• [Journal Article] Cerebellum, a target for hormonal signaling (2008)
  • Author(s): N. Koibuchi, et.al.
  • Journal Title: Cerebellum 7 Pages: 499-504
  • Peer Reviewed
• [Journal Article] Review : Gonadotropin-inhibitory hormone (GnIH) : biosynthesis, mode of action and functional significan ce in birds. (2008)
  • Author(s): K. Tsutsui and G. E. Bentley
  • Journal Title: Avian Biol. Res. 1 Pages: 175-186
  • Peer Reviewed
• [Journal Article] Review : Neurosteroids in the Purkinje cell : Biosynthesis, mode of action and functional significance. (2008)
  • Author(s): K. Tsutsui
  • Journal Title: Mol. Neurobiol 37 Pages: 116-125
  • Peer Reviewed
• [Journal Article] Review : Recent advances in reproductive neuroendocrinology : A role for the RFamide peptides in seasona I reproduction? (2008)
  • Author(s): T. J. Greives, et.al.
  • Journal Title: Proc. R. Soc. B. 275 Pages: 1943-1951
  • Peer Reviewed
• [Journal Article] Review : Progesterone biosynthesis and action in the developing neuron. (2008)
  • Author(s): K. Tsutsui
  • Journal Title: Endocrinology 149 Pages: 2757-2761
  • Peer Reviewed
• [Journal Article] Neurosteroid synthesis and action in the cerebellum during development (Review). (2008)
  • Author(s): K. Tsutsui
  • Journal Title: Cerebellum 7 Pages: 502-504
  • Peer Reviewed
• [Journal Article] Review : Expression, localization and possible actions of 25-Dx, a membrane-associated putative progest erone-binding protein, in the developing Purkinje cell of the cerebellum. (2008)
  • Author(s): H. Sakamoto, et.al.
  • Journal Title: Cerebellum 7 Pages: 18-25
  • Peer Reviewed
• [Journal Article] 生殖神経内分泌学の新たな展開 : GnIHとキスペプチンの発見 (2008)
  • Author(s): 筒井和義
  • Journal Title: 増刊号「ホルモンの病態異常と臨床検査」臨床検査Journal of Medioal Technology(医学書院) 52 Pages: 1207-1207
  • Peer Reviewed
• [Journal Article] GnlHと6niH同属ペプチド(LPXRFamideペプチド) : 構造と機能の普遍性と多様性 (2008)
  • Author(s): 筒井和義
  • Journal Title: 生化学 80 Pages: 849-854
  • Peer Reviewed
• [Journal Article] 総説 : ステロイドのnon-genomic action特集 : 合成ステロイドホルモン-最新の基礎・臨床研究- (2008)
  • Author(s): 徳元俊伸、筒井和義
  • Journal Title: 日本臨床 66 Pages: 70-76
  • Peer Reviewed
• [Journal Article] 7alpha-Hydroxypregnenolone mediates melatonin action underlying diurnal locomotor rhythms. (2008)
  • Author(s): K. Tsutsui et al.
  • Journal Title: J Neuroscience 28 Pages: 2158-2167
  • Peer Reviewed
• [Journal Article] Melatonin stimulates the release of growth hormone and prolactin by inducing the expression of frog growth hormone-releasing peptide and its related peptide-2 in the amphibian hypothalamus. (2008)
  • Author(s): V. S. Chowdhury et al.
  • Journal Title: Endocrinology 149 Pages: 962-970
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-reeasing hormone-l and-ll neurons in European starling brain. (2008)
  • Author(s): T. Ubuka et al.
  • Journal Title: Endocrinology 149 Pages: 268-278
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system. (2008)
  • Author(s): G. E. Bentley et al.
  • Journal Title: Gen. Comp. Endocrinol. 156 Pages: 34-43
  • Peer Reviewed
• [Journal Article] Photoperiod-independent hypothalamic regulation of luteinizing hormone secretion in a free-living Sonoran desert bird, the Rufous-winged Sparrow (Aimophila carpalis). (2008)
  • Author(s): T. W. Small et al.
  • Journal Title: Brain Behav. Evol. 71 Pages: 127-142
  • Peer Reviewed
• [Journal Article] Auditory stimulation of reproductive function in male Rufous-wingde Sparrows, Aimophila carpalis. (2008)
  • Author(s): T. W. Small et al.
  • Journal Title: Horm. Behav. 53 Pages: 28-39
  • Peer Reviewed
• [Journal Article] The orexigenic effect of GnlH is mediate by central opioid receptors in chicks. (2008)
  • Author(s): T. Tachibana et al.
  • Journal Title: Comp. Biochem. Phvsiol. (in press)
  • Peer Reviewed
• [Journal Article] Review: Neurosteroids in the Purkinje cell: Biosynthesis, mode of action and functional significance. (2008)
  • Author(s): K. Tsutsui
  • Journal Title: Mol. Neurobiol. (in press)
  • Peer Reviewed
• [Journal Article] Review: Recent advances in reproductive neuroendocrinology: A role for the RFamide peptides in seasonal reproduction? (2008)
  • Author(s): T. J, Greives et al.
  • Journal Title: Proc. R. Soc. B (in press)
  • Peer Reviewed
• [Journal Article] Review: Progesterone biosynthesis and action in the developing neuron. (2008)
  • Author(s): K. Tsutsui
  • Journal Title: Endocrinology (in press)
  • Peer Reviewed
• [Journal Article] Cerebellum, a target for hormonal signaling. (2008)
  • Author(s): N. Koibuchi et al.
  • Journal Title: Cerebellum (in press)
  • Peer Reviewed
• [Journal Article] Review: Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum. (2008)
  • Author(s): H. Sakamoto et al.
  • Journal Title: Cerebellum (in press)
  • Peer Reviewed
• [Journal Article] Neurosteroid synthesis and action in the cerebellum during development (Review). (2008)
  • Author(s): K.Tsutsui
  • Journal Title: Cerebellum (in press)
  • Peer Reviewed
• [Journal Article] Variability in preference for conspecific songs with syntactical complexity in female Bengalese finches: towards an understanding of song evolution. (2008)
  • Author(s): T.Morisaka et al.
  • Journal Title: Ornithol. Sci. (in press)
  • Peer Reviewed
• [Journal Article] Expression analysis of cadherins in the songbird brain: relationship to vocalsystem develooment. (2008)
  • Author(s): E.Matsunaga et al.
  • Journal Title: J.Comp. Neurol. 508 Pages: 329-342
  • Peer Reviewed
• [Journal Article] Sex differences in audiovisual discrimination learning by Bengalese finches (Lonchura striata var. domestics). (2008)
  • Author(s): Y.Seki et al.
  • Journal Title: J.Comp. Psvchol. 122 Pages: 25-34
  • Peer Reviewed
• [Journal Article] Genetic and developmental effects, and morphological influences on the acoustic structure of individual distance calls in female Bengalese finches Lonchura striata var. domestica. (2008)
  • Author(s): M.Soma et al.
  • Journal Title: J.Avian Biol. 39 Pages: 101-107
  • Peer Reviewed
• [Journal Article] Mode of action and functional significance of estrogen inducing dendritic growth, spinogenesis and synaptogenesis in the developing Purkinje cell (2007)
  • Author(s): K. Sasahara (筆頭著者), K. Tsutsui (最終著者), et al(著者7名)
  • Journal Title: J Neuroscience 27 Pages: 7408-7417
  • Peer Reviewed
• [Journal Article] Cerebellum, a target for hormonal signaling (2007)
  • Author(s): N. Koibuchi(筆頭著者), K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: Cerebellum 7 Pages: 499-504
  • Peer Reviewed
• [Journal Article] Mode of action and functional significance of estrogen inducing dendritic growth, spinogenesis and synaptogenesis in the developing Purkinje cell. (2007)
  • Author(s): K.Sasahara et al.
  • Journal Title: J Neuroscience 27 Pages: 7408-7417
  • Peer Reviewed
• [Journal Article] Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat. (2007)
  • Author(s): M. A. Johnson et al.
  • Journal Title: Horm Behav. 51 Pages: 171-180
  • Peer Reviewed
• [Journal Article] Review: Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance. (2007)
  • Author(s): K. Tsutsui et al.
  • Journal Title: J. Ornithol. 148
  • Peer Reviewed
• [Journal Article] Review: Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: Neuroanatomy and functional biology. (2007)
  • Author(s): G. E. Bentley et al.
  • Journal Title: J. Ornithol. 148
  • Peer Reviewed
• [Journal Article] Comparative reproductive neuroendocrinology. (2007)
  • Author(s): P. J. Sharp et al.
  • Journal Title: Gen. Comp. Endocrinol. 153 Pages: 344-345
  • Peer Reviewed
• [Journal Article] Review: The general and comparative biology of gonadotropin-inhibitory hormone(GnIH). (2007)
  • Author(s): K. Tsutsui et a1.
  • Journal Title: Gen. Comp. Endocrinol. 153 Pages: 365-370
  • Peer Reviewed
• [Journal Article] Sex-specific maternal effect on egg mass, laying order, and sibling competition in the Bengalese finch (Lonchura striata var. domestica). (2007)
  • Author(s): M. Soma et al.
  • Journal Title: Behav. Ecol. Sociobiol. 61 Pages: 1695-1705
  • Peer Reviewed
• [Journal Article] Cerebellum, a target for hormonal signaling. (2007)
  • Author(s): N.Koibuchi et al.
  • Journal Title: Cerebellum (in press)
• [Journal Article] Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat. (2007)
  • Author(s): M.A.Johnson et al.
  • Journal Title: Horm Behav. 51 Pages: 171-180
• [Journal Article] Neurosteroid synthesis and action in the cerebellum during development (Review). (2007)
  • Author(s): K.Tsutsui
  • Journal Title: Cerebellum (in press)
• [Journal Article] Review : Discovery of gonadotropin-inhibitory hormone in a domesticated bird, and its mode of action and functional significance. (2007)
  • Author(s): K.Tsutsui et al.
  • Journal Title: J. Ornithol. (in press)
• [Journal Article] Review : Gonadotropin-inhibitory hormone in seasonally-breeding songbirds : Neuroanatomy and functional biology. (2007)
  • Author(s): G.E.Bentley et al.
  • Journal Title: J. Ornithol. (in press)
• [Journal Article] Review : The general and comparative biology of gonadotropin-inhibitory hormone (GnIH). (2007)
  • Author(s): K.Tsutsui et al.
  • Journal Title: Gen. Comp. Endocrinol. Epub ahead of print
• [Journal Article] Control of luteinizing hormone and testosterone secretion in a flexibly breeding male passerine, the Rufous-winged Sparrow, Aimophila carpalis (2006)
  • Author(s): P. J. Deviche (筆頭著者), K. Tsutsui (最終著者), et al(著者4名)
  • Journal Title: Gen. Comp. Endocrinol. 149 Pages: 226-235
  • Peer Reviewed
• [Journal Article] Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family : Insights from novel lamprey RFamide peptides (2006)
  • Author(s): T. Osugi(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者5名)
  • Journal Title: FEBS Journal 273 Pages: 1731-1743
  • Peer Reviewed
• [Journal Article] Rapid inhibition of female sexual behavior by gonadotropin-inhibitory hormone (GnIH) (2006)
  • Author(s): G. E. Bentley(筆頭著者), K. Tsutsui(5番目), et al(著者6名)
  • Journal Title: Horm. Behav. 49 Pages: 550-555
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail (2006)
  • Author(s): T. Ubuka(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者5名)
  • Journal Title: Endocrinology 147 Pages: 1187-1194
  • Peer Reviewed
• [Journal Article] Novel hypothalamic neuropeptides stimulate the release of gonadotropins and growth hormone from the pituitary of sockeye salmon (2006)
  • Author(s): M. Amano(筆頭著), K. Ukena(7番目), K. Tsutsui(最終著者), et al(著者8名)
  • Journal Title: J. Endocrinology 188 Pages: 417-423
  • Peer Reviewed
• [Journal Article] Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals (2006)
  • Author(s): L. J. Kriegsfeld(筆頭著者), K. Ukena(7番目), K. Tsutsui(8番目), et al(著者9名)
  • Journal Title: Proc. Natl. Acad. Sci. USA 103 Pages: 103-103
  • Peer Reviewed
• [Journal Article] A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes (2006)
  • Author(s): O. Whitney(筆頭著者), S. Sakaguchi(8番目), et al(著者15名)
  • Journal Title: Proc. Natl. Acad. Sci. USA 103 Pages: 15212-15217
  • Peer Reviewed
• [Journal Article] Lesions of an avian forebrain nucleus prevent changes in protein kinase C levels associated with deafening-induced vocal plasticity in adult songbirds (2006)
  • Author(s): A. Watanabe(筆頭著者), K. Okanoya(3番目), S. Sakaguchi(最終著者), et al(著者4名)
  • Journal Title: Eur. J. Neurosci. 23 Pages: 1460-9568
  • Peer Reviewed
• [Journal Article] Review : Biosynthesis, mode of action and functional significance of neurosteroids in the developing Purkinje cell (2006)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: J. Steroid Biochem. Mol. Biol. 102 Pages: 187-194
  • Peer Reviewed
• [Journal Article] Review : Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell (2006)
  • Author(s): K. Tsutsui(単独著者)
  • Journal Title: Cerebellum 5 Pages: 89-96
  • Peer Reviewed
• [Journal Article] Review : Hypothalamic LPXRF-amide peptides in vertebrates : Identification, localization and hypophysiotropic activity (2006)
  • Author(s): K. Tsutsui(筆頭著者) and K. Ukena(最終著者)
  • Journal Title: Peptides 27 Pages: 1121-1129
  • Peer Reviewed
• [Journal Article] Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH): A review. (2006)
  • Author(s): K. Tsutsui(筆頭著者), K. Ukena(5番目), et al(著者11名)
  • Journal Title: J. Exp. Zool. 305A Pages: 801-806
  • Peer Reviewed
• [Journal Article] Neurosteroidbiosynthesis in the quail brain : A review (2006)
  • Author(s): K. Tsutsui(筆頭著者), K. Ukena(最終著者) et al(著者4名)
  • Journal Title: J. Exp. Zool. 305A Pages: 733-742
  • Peer Reviewed
• [Journal Article] Review : Neurosteroids in the brain neuron : Biosynthesis, action and medicinal impact on neurodegenerative disease (2006)
  • Author(s): K. Tsutsui(筆頭著者) and S. H. Mellon(最終著者)
  • Journal Title: Central Nerv. Syst. Agents Med. Chem. 6 Pages: 73-82
  • Peer Reviewed
• [Journal Article] 総説:鳥類における脳の性分化機構ホルモンと臨床 (2006)
  • Author(s): 筒井和義(筆頭著者)・加藤真樹・岡ノ谷一夫(最終著者)
  • Journal Title: 54 Pages: 13-20
  • Peer Reviewed
• [Journal Article] 総説:脳が合成するニューロステロイドと脳の自立的性分化機構 (2006)
  • Author(s): 筒井和義(単独著者)
  • Journal Title: 特集♂と♀のバイオロジー:生物の多様な性分化の仕組み細胞工学 25 Pages: 388-392
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail. (2006)
  • Author(s): T.Ubuka et al.
  • Journal Title: Endocrinology 147 Pages: 1187-1194
• [Journal Article] Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals. (2006)
  • Author(s): L.J.Kriegsfeld et al.
  • Journal Title: Proc. Natl. Acad. Sci. USA 103 Pages: 2410-2415
• [Journal Article] Novel fish hypothalamic neuropeptides stimulate the release of gonadotropins and growth hormone from the pituitary of sockeye salmon. (2006)
  • Author(s): M.Amano et al.
  • Journal Title: J. Endocrinology 188 Pages: 417-423
• [Journal Article] peptides in the RFamide peptide family : Insights from novel lamprey RFamide peptides. (2006)
  • Author(s): T.Osugi et al.
  • Journal Title: FEBS Journal 273 Pages: 1731-1743
• [Journal Article] Molecular cloning and functional characterization of a prolactin-releasing peptide homolog from Xenopus laevis. (2006)
  • Author(s): T.Sakamoto et al.
  • Journal Title: Peptides 27 Pages: 3347-3351
• [Journal Article] Rapid inhibition of female sexual behavior by gonadotropin-inhibitory hormone (GnIH) (2006)
  • Author(s): G.E.Bentley et al.
  • Journal Title: Horm. Behav. 49 Pages: 550-555
• [Journal Article] Control of luteinizing hormone and testosterone secretion in a flexibly breeding male passerine, the Rufous-winged Sparrow, Aimophila carpalis. (2006)
  • Author(s): P.J.Deviche et al.
  • Journal Title: Gen. Comp. Endocrinol. 149 Pages: 226-235
• [Journal Article] Gonadotropin-inhibitory hormone in birds : possible mode of action. (2006)
  • Author(s): G.E.Bentley et al.
  • Journal Title: Acta Zool Sinica. 52 Pages: 178-182
• [Journal Article] and the suprachiasmatic nucleus with the paraventricular organ in the Japanese grass lizard (Takydromus tachydromoides). (2006)
  • Author(s): E.Kawano et al.
  • Journal Title: Zool Sci. 23 Pages: 277-287
• [Journal Article] Review : Biosynthesis, mode of action and functional significance of neurosteroids in the developing Purkinje cell. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: J. Steroid Biochem. Mol. Biol. 102 Pages: 187-194
• [Journal Article] Review : Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: Cerebellum 5 Pages: 89-96
• [Journal Article] Review : Hypothalamic LPXRF-amide peptides in vertebrates : Identification, localization and hypophysiotropic activity. (2006)
  • Author(s): K.Tsutsui et al.
  • Journal Title: Peptides 27 Pages: 1121-1129
• [Journal Article] Review : Gonadotropin-Inhibitory Hormone (GnIH) : Discovery, Progress and Perspective. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: J. Poult. Sci. 43 Pages: 191-198
• [Journal Article] Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH) : A review. (2006)
  • Author(s): K.Tsutsui et al.
  • Journal Title: J. Exp. Zool. 305A Pages: 801-806
• [Journal Article] Review : Interactions of gonadotropin-releasing hormone (GnRH) and onadotropin-inhibitory hormone (GnIH) in birds and mammals. (2006)
  • Author(s): G.E.Bentley et al.
  • Journal Title: J. Exp. Zool. 305A Pages: 807-814
• [Journal Article] Structures and diverse functions of frog growth hormone-releasing peptide (fGRP) and its related peptides (fGRP-RPs) : A review. (2006)
  • Author(s): K.Ukena et al.
  • Journal Title: J. Exp. Zool. 305A Pages: 815-821
• [Journal Article] Neurosteroid biosynthesis in the quail brain : A review. (2006)
  • Author(s): K.Tsutsui et al.
  • Journal Title: J. Exp. Zool. 305A Pages: 733-742
• [Journal Article] Review : Neurosteroids in the brain neuron : Biosynthesis, action and medicinal impact on neurodegenerative disease. (2006)
  • Author(s): K.Tsutsui et al.
  • Journal Title: Central Nervous System Agents in Medicinal Chemistry 6 Pages: 73-82
• [Journal Article] Lesions of an avian forebrain nucleus prevent changes in protein kinase C levels associated with deafening-induced vocal plasticity in adult songbirds. (2006)
  • Author(s): A.Watanabe et al.
  • Journal Title: Eur J Neurosci 23 Pages: 1460-9568
• [Journal Article] Differential localization of protein kinase C isoforms in the song system of the zebra finch forebrain. (2006)
  • Author(s): H.Sakaguchi
  • Journal Title: Orthonological Sci 5 Pages: 31-37
  • NAID: 130004935008
• [Journal Article] A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes. (2006)
  • Author(s): O.Whitney et al.
  • Journal Title: Proc. Natl. Acad. Sci. USA 103 Pages: 15212-15217
• [Journal Article] Early rearing conditions affect the development of body size and song in Bengalese finches. (2006)
  • Author(s): M.Soma et al.
  • Journal Title: Ethology 112 Pages: 1071-1078
• [Journal Article] Non-singing female Bengalese finches (Lonchura striata var. domestica) possess neuronal projections connecting a song learning region to a song motor region. (2006)
  • Author(s): Y.Tobari et al.
  • Journal Title: Ornithological Science 5 Pages: 47-55
• [Journal Article] Trade-offs and correlations among multiple song traits in Bengalese finches. (2006)
  • Author(s): M.Soma et al.
  • Journal Title: Ornithological Science 5 Pages: 77-84
• [Journal Article] 総説 : 鳥類における脳の性分化機構 (2006)
  • Author(s): 筒井和義 et al.
  • Journal Title: ホルモンと臨床 54 Pages: 13-20
• [Journal Article] 総説 : 脳が合成するニューロステロイドと脳の自立的性分化機構 特集♂と♀のバイオロジー : 生物の多様な性分化の仕組み (2006)
  • Author(s): 筒井和義
  • Journal Title: 細胞工学 25 Pages: 388-392
• [Journal Article] 小鳥のさえずりの維持と可塑性-成鳥における聴覚フィードバックの役割について- (2006)
  • Author(s): 渡辺愛子 et al.
  • Journal Title: 比較生理生化学 23(1) Pages: 20-31
• [Journal Article] Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family : Insights from novel lamprey RFamide peptides. (2006)
  • Author(s): T.Osugi
  • Journal Title: FEBS Journal (in press)
• [Journal Article] Lesions of an avian forebrain nucleus prevent changes in protein kinase C levels associated with deafening-induced vocal plasticity in adult songbirds. (2006)
  • Author(s): A.Watanabe
  • Journal Title: Eur.J.Neurosci. (in press)
• [Journal Article] Neural interaction of gonadotropin-regulating hormone immunoreactive neurons and the suprachiasmatic nucleus with the paraventricular organ in the Japanese grass lizard (Takydromus tachydromoides). (2006)
  • Author(s): E.Kawano
  • Journal Title: Zool Sci. (in press)
• [Journal Article] Review : Hypothalamic LPXRF-amide peptides in vertebrates : Identification, localization and hypophysiotropic activity. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: Peptides (in press)
• [Journal Article] Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH) : A review. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: J.Exp.Zool. (in press)
• [Journal Article] Review : Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals. (2006)
  • Author(s): G.E.Bentley
  • Journal Title: J.Exp.Zool. (in press)
• [Journal Article] Structures and diverse functions of frog growth hormone-releasing peptide (fGRP) and its related peptides (fGRP-RPs) : A review. (2006)
  • Author(s): K.Ukena
  • Journal Title: J.Exp.Zool. (in press)
• [Journal Article] Neurosteroid biosynthesis in the quail brain : A review. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: J.Exp.Zool. (in press)
• [Journal Article] Review : Gonadotropin-Inhibitory Hormone (GnIH) : Discovery, Progress and Perspective. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: J.Poult.Sci. (in press)
• [Journal Article] Rapid inhibition of female sexual behavior by gonadotropin-inhibitory hormone (GnIH). (2006)
  • Author(s): G.E.Bentley
  • Journal Title: Horm.Behav 49 Pages: 550-555
• [Journal Article] Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail. (2006)
  • Author(s): T.Ubuka
  • Journal Title: Endocrinology 147 Pages: 1187-1194
• [Journal Article] Novel fish hypothalamic neuropeptides stimulate the release of gonadotropins and growth hormone from the pituitary of sockeye salmon. (2006)
  • Author(s): M.Amano
  • Journal Title: J.Endocrinology 188 Pages: 417-423
• [Journal Article] Identification and characterization of a gonadotropin-inhibitory system in the brain of mammals. (2006)
  • Author(s): L.J.Kriegsfeld
  • Journal Title: Proc.Natl.Acad.Sci.USA 103 Pages: 2410-2415
• [Journal Article] Review : Neurosteroids in the brain neuron : Biosynthesis, action and medicinal impact on neurodegenerative disease. (2006)
  • Author(s): K.Tsutsui
  • Journal Title: Central Nervous System Agents in Medicinal Chemistry 6 Pages: 73-82
• [Journal Article] 総説:脳が合成するニューロステロイドと脳の自立的性分化機構 特集 ♂と♀のバイオロジー:生物の多様な性分化の仕組み (2006)
  • Author(s): 筒井和義
  • Journal Title: 細胞工学 25 Pages: 388-392
• [Journal Article] Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain,Nature Reviews Highlight (2005)
  • Author(s): T. Ubuka(筆頭著者), K. Ukena(3番目), K. Tsutsui(最終著者), et al(著者5名)
  • Journal Title: Proc. Natl. Acad. Sci. USA, Nat. Rev. Neurosci. 102,6
  • Peer Reviewed
• [Journal Article] A novel G protein-coupled receptor for gonadotropin- inhibitory hormone in the Japanese quail (Coturnix japonica) : identification, expression and binding activity (2005)
  • Author(s): H. Yin(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: J. Endocrinology 184 Pages: 257-266
  • Peer Reviewed
• [Journal Article] Review : A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides : Structure, localization and function (2005)
  • Author(s): K. Ukena(筆頭著者) and K. Tsutsui(最終著者)
  • Journal Title: Spectrom. Rev. 24 Pages: 469-486
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks. (2005)
  • Author(s): T.Tachibana
  • Journal Title: Brain Res. 1050 Pages: 94-100
• [Journal Article] Expression of aromatase mRNA in the abdominal gland of the newt, Cynops pyrrhogaster. (2005)
  • Author(s): Y.Ito
  • Journal Title: Ann.N.Y.Acad.Sci. 1040 Pages: 348-350
• [Journal Article] Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain. (2005)
  • Author(s): T.Ubuka
  • Journal Title: Proc.Natl.Acad.Sci.USA [Nature Reviews Highlight] 102 Pages: 3052-3057
• [Journal Article] A novel G protein-coupled receptor for gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica) : identification, expression and binding activity. (2005)
  • Author(s): H.Yin
  • Journal Title: J.Endocrinology 184 Pages: 257-266
• [Journal Article] Review : Gonadotropin-inhibitory hormone (GnIH). (2005)
  • Author(s): K.Tsutsui
  • Journal Title: Jpn.J.Reprod.Endocrinol. 10 Pages: 49-53
• [Journal Article] Review : A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides : Structure, localization and function. (2005)
  • Author(s): K.Ukena
  • Journal Title: Mass Spectrometry Reviews 24 Pages: 469-486
• [Journal Article] 総説:発達期の小脳プルキンエ細胞における25-Dxの発現-プルキンエ細胞が合成するプロゲステロンの作用機構-特集:脳の遺伝子-どこでどのように働いているのか (2005)
  • Author(s): 筒井和義
  • Journal Title: 生体の科学 56 Pages: 296-302
• [Journal Article] Sex differences in the telencephalic song control circuitry in Bengalese finches (Lonchura striata var.domestica). (2005)
  • Author(s): Y.Tobari
  • Journal Title: Zool.Sci. 22 Pages: 1089-1094
• [Journal Article] Review : Hypothalamic LPXRF-amide peptides in vertebrates : Identification, localization and hypophysiotropic activity. (2005)
  • Author(s): K.Tsutsui
  • Journal Title: Peptides In press(印刷中)
• [Journal Article] Review : A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides : Structure, localization and function. (2005)
  • Author(s): K.Ukena
  • Journal Title: Mass Spectrometry Reviews In press(印刷中)
• [Journal Article] Review : Organizing actions of neurosteroids in the Purkinje neuron. (2005)
  • Author(s): K.Tsutsui
  • Journal Title: Neurosci.Res. 49 Pages: 273-279
• [Journal Article] Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain. (2005)
  • Author(s): T.Ubuka
  • Journal Title: Proc.Natl.Acad.Sci.USA(プレスリリース:米国のThe Scientist, Reuters, Health Magazine,読売新聞,日経新聞、共同通信,NHK) 102 Pages: 3052-3057
• [Journal Article] A novel G protein-coupled receptor for gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica):identification, expression and binding activity. (2005)
  • Author(s): H.Yin
  • Journal Title: J.Endocrinology 184 Pages: 257-266
• [Journal Article] 7・-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system (2004)
  • Author(s): M. Matsunaga(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: Proc. Natl. Acad. Sci. USA 101 Pages: 17282-17287
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone in Gambel's white-crowned sparrow : cDNA identification, transcript localization and functional effects in laboratory and field experiments (2004)
  • Author(s): T. Osugi(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者7名)
  • Journal Title: J. Endocrinology 182 Pages: 33-42
  • Peer Reviewed
• [Journal Article] Expression and localization of 25-Dx, a membrane-associated putative progesterone- binding protein, in the developing Purkinje cell (2004)
  • Author(s): H. Sakamoto(筆頭著者), K. Ukena(2番目), K. Tsutsui(最終著者), et al(著者6名)
  • Journal Title: Neuroscience 126 Pages: 325-334
  • Peer Reviewed
• [Journal Article] Identification of 3・, 5・-tetrahydroprogesterone,a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain (2004)
  • Author(s): M. Matsunaga(筆頭著者), K. Ukena(3番目) K. Tsutsui(最終著者), et al(著者4名)
  • Journal Title: Brain Res. 1007 Pages: 160-166
  • Peer Reviewed
• [Journal Article] Differential expression of glutamate receptors in avian neural pathways for learned vocalization. (2004)
  • Author(s): K.Wada
  • Journal Title: J.Comp.Neurol. 476 Pages: 44-64
• [Journal Article] Effect of social factors on the development of PKC expression in songbird brain. (2004)
  • Author(s): H.Sakaguchi
  • Journal Title: NeuroReport 15 Pages: 2819-2823
• [Journal Article] Gonadotrophin inhibitory hormone depresses gonadotrophin α and follicle-stimulating hormone β subunit expression in the pituitary of the domestic chicken. (2004)
  • Author(s): N.A.Ciccone
  • Journal Title: J.Neuroendocrinology 16 Pages: 999-1006
• [Journal Article] 7α-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system. (2004)
  • Author(s): M.Matsunaga
  • Journal Title: Proc.Natl.Acad.Sci.USA(プレスリリース:読売新聞、NHKなど) 101 Pages: 17282-17287
• [Journal Article] Does gonadotrophin inhibiting hormone (GnIH) play a functional role in avian reproduction? (2004)
  • Author(s): N.A.Ciccone
  • Journal Title: Br.Poult.Sci. 45 Pages: 28-29
• [Journal Article] Gonadotropin-inhibitory hormone in Gambel's white-crowned sparrow : cDNA identification, transcript localization and functional effects in laboratory and field experiments. (2004)
  • Author(s): T.Osugi
  • Journal Title: J.Endocrinology 182 Pages: 33-42
• [Journal Article] Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell. (2004)
  • Author(s): H.Sakamoto
  • Journal Title: Neuroscience 126 Pages: 325-334
• [Journal Article] Dendritic growthin response to environmental estrogens in the developing Purkinje cell. (2004)
  • Author(s): H.Shikimi
  • Journal Title: Neurosci.Lett. 364 Pages: 114-118
• [Journal Article] Expression and distribution of octopus GnRH in the central nervous system and peripheral organs of the octopus (Octopus vulgaris) by in situ hybridization and immunohistochemistry. (2004)
  • Author(s): E.Iwakoshi-Ukena
  • Journal Title: J.Comp.Neurol. 477 Pages: 310-323
• [Journal Article] Photoperiodic response of serotonin- and galanin-immunoreactive neurons of the paraventricular organ and infundibular nucleus in Japanese quail, Coturnix coturnix japonica. (2004)
  • Author(s): Y.Haida
  • Journal Title: Zool.Sci. 21 Pages: 575-582
• [Journal Article] Identification of 3β,5β-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain. (2004)
  • Author(s): M.Matsunaga
  • Journal Title: Brain Res. 1007 Pages: 160-166
• [Journal Article] Neural correlates of song complexity in Bengalese finch high vocal center. (2004)
  • Author(s): K.Z.Nakamura
  • Journal Title: NeuroReport 15 Pages: 1359-1363
• [Journal Article] Song syntax in Bengalese finches : proximate and ulitimate analyses. (2004)
  • Author(s): K.Okanoya
  • Journal Title: Adva.Stud.Behavior 34 Pages: 297-341
• [Journal Article] The Bengalese finch : a window on the behavioral neurobiology of bird song syntax. (2004)
  • Author(s): K.Okanoya
  • Journal Title: Ann.N.Y.Acad.Sci. 1016 Pages: 724-735
• [Journal Article] Functional and structural pre-adaptations to language : insight from comparative cognitive science into the study of language origin. (2004)
  • Author(s): K.Okanoya
  • Journal Title: Jpn.Psychol.Research 46 Pages: 207-215
• [Journal Article] Spontaneous construction of "Chinese boxes" by Degus(Octodon degu):A rudiment of recursive intelligence? (2004)
  • Author(s): N.Tokimoto
  • Journal Title: Jpn.Psychol.Research 46 Pages: 255-261
• [Journal Article] Estimation of hearing range in raptors using unconditioned responses. (2004)
  • Author(s): Y.Yamazaki
  • Journal Title: Ornithol.Science 3 Pages: 85-92
• [Presentation] Gonadotropin-inhibitory hormone (GnIH) : discovery, progress and prospect (2008)
  • Author(s): K. Tsutsui
  • Organizer: prospectThe 5th International Symposium on Molecular Endocrinology
  • Place of Presentation: Gwangju, Korea(基調講演)
  • Year and Date: 2008-04-04
• [Presentation] Gonadotropin-inhibitory hormone (GnIH) : discovery, progress and prospect (2008)
  • Author(s): K. Tsutsui
  • Organizer: The 5th International Symposium on Molecular Endocrinology
  • Place of Presentation: Gwangju, Korea.
  • Year and Date: 2008-04-04
• [Presentation] The novel neurosteroid 7alpha-hydroxypregnenolone is a key factor inducing sex-dependent locomotor activity (2008)
  • Author(s): K. Tsutsui
  • Organizer: 第85日本生理学会シンポジウム「性差の分子メカニズム Moiecular Mechanisms of Sexual Differences」
  • Place of Presentation: 京王プラザホテル
  • Year and Date: 2008-03-27
• [Presentation] GnlHとGnlH同族ペプチドの多様性と分子進化 (2008)
  • Author(s): 筒井和義
  • Organizer: 基礎生物学研究所研究会「生殖生物学の歴史と展望」
  • Place of Presentation: 岡崎力ンファレンス
  • Year and Date: 2008-03-24
• [Presentation] Novel molecular mechanism inducing sex difference in locomotor activity by 7・-hydroxypregnenolone, a newly discovered neurosteroid (2008)
  • Author(s): K. Tsutsui
  • Organizer: International Symposium for Gonad and Brain Sex Differentiation
  • Place of Presentation: Fukuoka, Japan(招待講演)
• [Presentation] Discovery of gonadotropin-inhibitory hormone (GnIH), and its mode of action and functional significance (2008)
  • Author(s): K.Tsutsui
  • Organizer: US/Japan International Symposium on Neurosteroids
  • Place of Presentation: Gifu, Japan(招待講演)
• [Presentation] Identification, biosynthesis and function of 7・-hydroxypregnenolone, a new key neurosteroid controlling locomotor activity (2008)
  • Author(s): K. Tsutsui
  • Organizer: The 24th Conference European Comparative Endocrinologists
  • Place of Presentation: Genova, Italy(招待講演)
• [Presentation] Evolutionary origin and divergence of GnIH and its homologous peptides (2008)
  • Author(s): K. Tsutsui
  • Organizer: The 6th International Symposium on Fish Endocrinology and Neuroendocrinology
  • Place of Presentation: Calgary, Canada(基調講演)
• [Presentation] Novel molecular mechanism inducing sex difference in locomotor activity by 7alpha-hydroxypregnenolone, a newly discovered neurosteroid. (2008)
  • Author(s): K. Tsutsui
  • Organizer: International Symposium for Gonad and Brain Sex Differentiation
  • Place of Presentation: Fukuoka, Japan
• [Presentation] Discovery of gonadotropin-inhibitory hormone(GnIH), and its mode of action and functional significance. (2008)
  • Author(s): K. Tsutsui
  • Organizer: US/Japan International Symposium on Neurosteroids
  • Place of Presentation: Gifu, Japan
• [Presentation] Rapid stimulation of locomotor activity by 7alpha-hydroxypregnenolone identified as a novel neuronal a ctivator. (2008)
  • Author(s): S. Haraguchi and K. Tsutsui
  • Organizer: US/Japan International Symposium on Neurosteroids
  • Place of Presentation: Gifu, Japan
• [Presentation] Identification, biosynthesis and function of 7alpha-hydroxypregnenolone, a new key neurosteroid contro fling locomotor activity. (2008)
  • Author(s): K. Tsutsui.
  • Organizer: The 24th Conference European Comparative Endocrinologists
  • Place of Presentation: Genova, Italy
• [Presentation] Hormone-mediated reproductive behavior in the newt (2008)
  • Author(s): S. Kikuyama and K. Tsutsui
  • Organizer: The 24th Conference European Comparative Endocrinologists
  • Place of Presentation: Genova, Italy
• [Presentation] The novel avian neurosteroid 7alpha-hydroxypregnenolone mediates melatonin action underlying diurnal I ocomotor rhythms. (2008)
  • Author(s): K. Tsutsui
  • Organizer: The 9th International Symposium on Avian Endocrinology
  • Place of Presentation: Leuven, Belgium
• [Presentation] Neurosteroid synthesis and action in the cerebellar Purkinje cell (2007)
  • Author(s): K.Tsutsui
  • Organizer: 第30回日本分子生物学会年会・第80回日本生化学会大会合同大会シンポジウム「局所ステロイドの合成と機能」
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2007-12-12
• [Presentation] イモリから同定した新規ニューロステロイドの生理作用 (2007)
  • Author(s): 筒井和義
  • Organizer: 日本動物学会第78回大会シンポジウム「両生類はワンダーランド」
  • Place of Presentation: 弘前大学
  • Year and Date: 2007-09-22
• [Presentation] ニューロステロイド合成の日周性とメラトニンによる調節 (2007)
  • Author(s): 筒井和義
  • Organizer: 第29回日本比較生理生化学会シンポジウム「生体リズムにおける振動制御機構と出力機構〜研究の現状と新展開〜」
  • Place of Presentation: 岡山大学
  • Year and Date: 2007-07-06
• [Presentation] 鳥類から発見された生殖腺刺激ホルモン放出抑制ホルモン(GnlH)とその受容体 (2007)
  • Author(s): 筒井和義
  • Organizer: 第4回GPCR研究会シンポジウム「GPCRと内分泌・生殖機能」
  • Place of Presentation: 日本科学未来館
  • Year and Date: 2007-05-12
• [Presentation] The novel avian neurosteroid 7・-hydroxypregnenolone mediates melatonin action underlying diurnal locomotor rhythms (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 9th International Symposium on Avian Endocrinology
  • Place of Presentation: Leuven, Belgium(Farner Medal受賞講演)
• [Presentation] Gonadotropin-inhibitory hormone (GnIH) in a new reproductive axis (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 6th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Siliguri, India(基調講演)
• [Presentation] Gonadotropin-inhibitory hormone (GnIH) : discovery, mode of action, functional significance and prospective application to reproductive dysfunction (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 5th Anniversary Congress of International Drug Discovery Science and Technology (IDDST)-2007
  • Place of Presentation: Xi'an, China(招待講演)
• [Presentation] Melatonin regulates the production of 7・-hydroxypregnenolone identified as an active neurosteroid stimulating locomotor activity in vertebrates (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 2nd World Congress of Chronobiology
  • Place of Presentation: Tokyo, Japan(招待講演)
• [Presentation] Structures, diverse actions and functional significance of frog growth hormone-releasing peptide (fGRP) and its related peptides (fGRP-RPs) (2007)
  • Author(s): K. Tsutsui
  • Organizer: International Symposium on Amphibian and Reptile Endocrinology and Neurobiology
  • Place of Presentation: Berkeley, California, USA(基調講演)
• [Presentation] Gonadotropin-inhibitory hormone (GnIH): discovery, mode of action, functional significance and prospective application to reproductive dysfunction (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 5th Anniversary Congress of International Drug Discovery Science and Technology (IDDST)-2007
  • Place of Presentation: Xi'an, China
• [Presentation] Melatonin regulates the production of 7alpha-hydroxypregnenolone identified as an active neurosteroid stimulating locomotor activity in vertebrates (2007)
  • Author(s): K. Tsutsui
  • Organizer: The 2nd World Congress of Chronobiology
  • Place of Presentation: Tokyo, Japan
• [Presentation] The comparative biology of gonadotrophin-inhibitory hormone (GnIH) and its homologous peptides (2006)
  • Author(s): K. Tsutsui
  • Organizer: The23rdConference of European Comparative Endocrinologists
  • Place of Presentation: Manchester, UK(基調講演)
• [Presentation] Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance (2006)
  • Author(s): K. Tsutsui
  • Organizer: The24thInternational Ornithological Congress
  • Place of Presentation: Hamburg, Germany(基調講演)
• [Presentation] Dendritic growth, spinogenesis and synaptogenesis in response to neurosteroids in the developing Purkinje cell (2006)
  • Author(s): K. Tsutsui
  • Organizer: InternationalSymposium on Hormonal Regulation on Neurons and Network : Synaptogenesis to Behavior, The 29th Annual Meeting(Neuroscience 2006) of the Japan Neuroscience Society
  • Place of Presentation: Kyoto, Japan(招待講演)
• [Presentation] Biosynthesis, mode of action and functional significance of neurosteroids in the developing Purkinje cell (2006)
  • Author(s): K. Tsutsui
  • Organizer: The 17th International Symposium of the Journal of Steroid Biochemistry and Molecular Biology
  • Place of Presentation: Seefeld, Tyrol, Austria(招待講演)
• [Presentation] Neurosteroid biosynthesis and function in the quail brain (2005)
  • Author(s): K. Tsutsui
  • Organizer: The15thInternationalCongressofComparative Endocrinology
  • Place of Presentation: Boston, Massachusetts, USA(招待講演)
• [Presentation] Mode of action and functional significance of avian gonadotropin-inhibitory hormone(GnIH) (2005)
  • Author(s): K. Tsutsui
  • Organizer: The 15thInternationalCongressofComparative Endocrinology
  • Place of Presentation: Boston, Massachusetts, USA(招待講演)
• [Presentation] Molecular evolution of the RF-amide peptide family (2005)
  • Author(s): K. Tsutsui
  • Organizer: Satellite Workshop on Reproductive Endocrine System in Agnathans and Protochordates of the 15th International Congress of Comparative Endocrinology
  • Place of Presentation: Boston, Massachusetts, USA(招待講演)
• [Presentation] Discovery of gonadotropin-inhibitory hormone (GnIH) and its mode of action and functional significance (2005)
  • Author(s): K.Tsutsui
  • Organizer: ISCE Symposium on "Comparative Endocrinology and Reproductive Physiology: Retrospect and Prospect"
  • Place of Presentation: New Delhi, India(特別講演)
• [Presentation] Synapse formation in response to neurosteroids in the Purkinje neuron (2004)
  • Author(s): K. Tsutsui
  • Organizer: The 7th International Symposium on Molecular Medicine
  • Place of Presentation: Crete, Greece(招待講演)
• [Presentation] Probing neurosteroids and novel neuropeptides in the avian brain : discovery, progress and perspective (2004)
  • Author(s): K. Tsutsui
  • Organizer: The8thInternational Symposium on Avian Endocrinology
  • Place of Presentation: Phoenix, Arizona, USA(基調講演)
• [Presentation] GnIH and its related peptides in the quail brain : Identification, localization and function (2004)
  • Author(s): K. Ukena and K. Tsutsui
  • Organizer: The8thInternationalSymposiumonAvianEndocrinology
  • Place of Presentation: Phoenix, Arizona, USA(基調講演)
• [Presentation] Classical and novel neurosteroids in vertebrate brains (2004)
  • Author(s): K. Tsutsui
  • Organizer: The 5th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Nara, Japan(招待講演)
• [Book] Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain (2007)
  • Author(s): K. Tsutsui, T. Ubukaand G.E.Bentley
  • Total Pages: 14
  • Publisher: In : Melatonin : From Molecules to Therapy, (S. R. Pandi-PerumalandD. P. Cardinali (eds) NovaScience Publishers, New York)
• [Book] Gonadotropin-inhibitory hormone (GnIH) in the avian brain (2007)
  • Author(s): K. Tsutsui
  • Total Pages: 7
  • Publisher: In : Hormone Biotechnology(S. K. Maitra (ed), Daya Publishing House, Delhi)
• [Book] Neuronal neurosteroidogenesis and organizing actions of neurosteroids during cerebellar development (2007)
  • Author(s): K.Tsutsui
  • Total Pages: 18
  • Publisher: In : Evolutionary Molecular Strategies and Plasticity(M. Canonaco and R. M. Facciolo (eds) Research SignpostPublishers,Trivandrum)
• [Book] Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain. In: Melatonin: From Molecules to TheraPy. (2007)
  • Author(s): K. Tsutsui et al.
  • Total Pages: 14
  • Publisher: Nova Science Publishers, New York
• [Book] Gonadotropin-inhibitory hormone (GnIH) in the avian brain. In: Hormone Biotechnology. (2007)
  • Author(s): K. Tsutsui
  • Total Pages: 7
  • Publisher: Daya Publishing House, Delhi
• [Book] Neuronal neurosteroidogenesis and organizing actions of neurosteroids during cerebellar development. In: Evolutionary Molecular Strategies and Plasticity. (2007)
  • Author(s): K. Tsutsui
  • Total Pages: 18
  • Publisher: Research Signpost Publishers, Trivandrum
• [Book] 脳ホルモン新領域シリーズ21世紀の動物科学10内分泌と生命現象第5章脳ホルモンの新領域長濱嘉孝・井口泰泉共編 (2007)
  • Author(s): 筒井和義, et. al.
  • Total Pages: 39
  • Publisher: 培風館
• [Book] ホルモンハンドブック新訂eBook版脂溶性情報分子(細胞内受容体結合分子ファミリー)日本比較内分泌学会編 (2007)
  • Author(s): 筒井和義
  • Total Pages: 130
  • Publisher: 南江堂
• [Book] Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain. (2007)
  • Author(s): K.Tsutsui et al.
  • Publisher: In : Melatonin : From Molecules to Therapy, S.R. Pandi-Perumal and D. P. Cardinali (eds) Nova Science Publishers, New York(in press)
• [Book] Gonadotropin-inhibitory hormone (GnIH) in the avian brain. (2007)
  • Author(s): K.Tsutsui
  • Total Pages: 7
  • Publisher: In : Hormone Biotechnology, S.K. Maitra (ed), Daya Publishing House, Delhi
• [Book] Neuronal neurosteroidogenesis and organizing actions of neurosteroids during cerebellar development. (2007)
  • Author(s): K Tsutsui
  • Total Pages: 18
  • Publisher: In : Evolutionary Molecular Strategies and Plasticity, M. Canonaco and R. M. Facciolo (eds) Research Signpost Publishers, Trivandrum, India
• [Book] Endocrinology of reproduction (2006)
  • Author(s): G. E. Bentley, K. Tsutsuiand J. C. Wingfield
  • Total Pages: 62
  • Publisher: In : ReproductiveBiologyandPhylogeny of Birds(Barrie G. M. Jamieson (ed) Science Publishers, Enfield, USA)
• [Book] The Rfamide-related peptides (2006)
  • Author(s): N. Chartrel, K. Tsutsui, J. Costentin and H. Vaudry
  • Total Pages: 8
  • Publisher: In : The Handbook of Biologically Active Peptides(In : The Handbook of Biologically Active Peptides)
• [Book] Endocrinology of reproduction. (2006)
  • Author(s): G.E.Bentley et al.
  • Total Pages: 62
  • Publisher: In : Reproductive Biology and Phylogeny of Birds, Barrie G.M. Jamieson (ed) Science Publishers, Enfield, USA
• [Book] Avian gonadotropin-inhibitory hormone (GnIH) : Identification, mode of action and functional significance. (2006)
  • Author(s): K.Tsutsui
  • Total Pages: 5
  • Publisher: In : Comparative Endocrinology and Biodiversity in Asia and Oceania, P. Tangpraprutgul et al. (eds) Chulalongkorn University Press, Bangkok
• [Book] Melatonin action on the induction of gonadotropin-inhibitory hormone in the avian brain. (2006)
  • Author(s): V.S.Chowdhurv et al.
  • Total Pages: 4
  • Publisher: In : Comparative Endocrinology and Biodiversity in Asia and Oceania, P. Tangpraprutgul et al. (eds) Chulalongkorn University Press, Bangkok
• [Book] The RFamide-related peptides (2006)
  • Author(s): N.Chartrel et al.
  • Total Pages: 8
  • Publisher: In : The Handbook of Biologically Active Peptides, A. J. Kastin (ed) Elsevier publisher
• [Book] Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain. (In : MELATONIN : from Molecules to Therapy)(S.R.Pandi-Perumal and D.P.Cardinali (eds)) (2006)
  • Author(s): K.Tsutsui
  • Publisher: Nova Science Publishers, New York(in press)
• [Book] Gonadotropin-inhibitory hormone (GnIH) in the avian brain. (In : Hormone Biotechnology)(S.K.Maitra (ed)) (2006)
  • Author(s): K.Tsutsui
  • Publisher: M/S Daya Publishing House, Delhi(in press)
• [Book] The RFamide-related peptides (In : The Handbook of Biologically Active Peptides)(A.J.Kastin (ed)) (2006)
  • Author(s): N.Chartrel
  • Total Pages: 8
  • Publisher: Elsevier publisher
• [Book] Avian gonadotropin-inhibitory hormone (GnIH) : Identification, mode of action and functional significance.(In : Comparative Endocrinology and Biodiversity in Asia and Oceania)(P.Tangpraprutgul et al. (eds)) (2006)
  • Author(s): K.Tsutsui
  • Total Pages: 5
  • Publisher: Chulalongkorn University Press, Bangkok, Thailand
• [Book] Melatonin action on the induction of gonadotropin-inhibitory hormone in the avian brain.(In : Comparative Endocrinology and Biodiversity in Asia and Oceania)(P.Tangpraprutgul et al. (eds)) (2006)
  • Author(s): V.S.Chowdhury
  • Total Pages: 4
  • Publisher: Chulalongkorn University Press, Bangkok, Thailand
• [Book] Structure, action and functional significance of GnIH (2005)
  • Author(s): K. Tsutsui, G. Bentley and N. Ciccone
  • Total Pages: 10
  • Publisher: In : Functional Avian Endocrinology(A. Dawson and P. J. Sharp (eds) Narosa Publishing House, New Delhi)
• [Book] Structure, action and functional significance of GnIH.(In : Functional Avian Endocrinology)(A.Dawson and P.J.Sharp (eds)) (2005)
  • Author(s): K Tsutsui
  • Total Pages: 10
  • Publisher: Narosa Publishing House, New Delhi
• [Book] Trends in Comparative Endocrinology (2004)
  • Author(s): T. Oishi, K. Tsutsui, S. Tanaka and S. Kikuyama
  • Total Pages: 593
  • Publisher: AOSCE
• [Book] Treads in Comparative Endocrinology (2004)
  • Author(s): K.Tsutsui
  • Total Pages: 593
  • Publisher: Asia and Oceania Society for Comparative Endocrinology
• [Book] Classical and novel neurosteroids in vertebrate brains. Trends in Comparative Endocrinology (T.oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): K.Tsutsui
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] Synapse formation in response to estrogen synthesized de novo in the developing Purkinje cell. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): H.Shikimi
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] A novel amphibian neurosteroid stimulating locomotor activity. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): M.Matsunaga
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] Comparative aspects of novel hypothalamic LPXRF-amide peptides in the vertebrate brain : Structure, localization and function. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): K.Ukena
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] Novel avian neurosteroid : Identification of 7a-hydroxypregnenolone in the quail brain. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, and S.Kikuyama (eds)) (2004)
  • Author(s): H.Miyabara
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] Identification and localization of a novel lamprey hypothalamic neuropeptide of the RF-amide peptide family. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): T.Osugi
  • Total Pages: 3
  • Publisher: AOSCE
• [Book] Effects of RF-amide peptides on the release of TSH from the bullfrog pituitary. Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka and S.Kikuyama (eds)) (2004)
  • Author(s): K.Yamamoto
  • Total Pages: 3
  • Publisher: AOSCE
• [Remarks] 2008年3月2日読売新聞掲載
• [Remarks] 2008年3月2日YOMIURI ONLINE掲載
• [Remarks] 2008年7月15日Farner Medal受賞(International Society for Avian Endocrinology)
• [Remarks] 2007年9月10日asahi.com OPINION(朝日新聞社報)掲載
  • URL: http://www.f.waseda.jp/k-tsutsui/
• [Remarks]
  • URL: http://vnwi.f.waseda.jp/k-tsutsui/fworks.htmI
• [Remarks]
  • URL: http://www.f.waseda.jp/k-tsutsui/
• [Patent(Industrial Property Rights)] 新規メタスチン同族体およびその用途 (2009)
  • Inventor(s): 筒井和義
  • Industrial Property Rights Holder: 筒井和義
  • Industrial Property Number: 2008-253859
  • Acquisition Date: 2009-09-30
  • Acquisition Year: 2009
• [Patent(Industrial Property Rights)] 新規メタスチン同族体およびその用途 (2008)
  • Inventor(s): 筒井和義
  • Industrial Property Rights Holder: 筒井和義
  • Industrial Property Number: 2008-253859
  • Filing Date: 2008-09-30
  • Application Year: 2008