Studying on Switching of Reproductive System in Planarian
| Project/Area Number |
16086209
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Keio University |
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Principal Investigator |
MATSUMOTO Midori Keio University, 理工学部, 准教授 (00211574)
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| Co-Investigator(Kenkyū-buntansha) |
HOSHI Motonori 放送大学, 教養学部, 教授 (20012411)
KOBAYASHI Kazuya 慶應義塾大学, 理工学部, 助教 (50360110)
TAKEDA Noriyo 慶應義塾大学, 理工学部, 助手 (40433742)
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| Project Period (FY) |
2004 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥48,000,000 (Direct Cost: ¥48,000,000)
Fiscal Year 2008: ¥9,600,000 (Direct Cost: ¥9,600,000)
Fiscal Year 2007: ¥9,600,000 (Direct Cost: ¥9,600,000)
Fiscal Year 2006: ¥9,600,000 (Direct Cost: ¥9,600,000)
Fiscal Year 2005: ¥9,600,000 (Direct Cost: ¥9,600,000)
Fiscal Year 2004: ¥9,600,000 (Direct Cost: ¥9,600,000)
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| Keywords | 無性生殖 / 有性生殖 / プラナリア / 生殖様式 / D-アミノ酸 / Piwi / ネオブラスト / 有性化因子 / ESTデータベース / 生殖戦略 / 有性化物質 / ESTデータベー |
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| Research Abstract |
独自に開発したプラナリア無性生殖個体を有性生殖個体に転換させる系(有性化)を用いて、(1)有性化因子の単離、(2)有性化関連遺伝子群の解析、(3)全能性幹細胞ネオブラストの生殖細胞分化能について研究を進めてきた。有性化因子の一つとしてD-Trpが卵巣の顕著な発達と異所的な卵巣形成を誘導することを示し、有性化誘導初期に発現する遺伝子群を探索し見いだした。また、誕生時の生殖様式によってネオブラストの生殖細胞への分化能が異なることが示した。
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Report
(6 results)
Research Products
(64 results)
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[Journal Article] The Dugesia ryukyuensis Database as a Molecular Resource for Studying on Switching of Reproductive System2007
Author(s)
Hideyuki Ishiduka, Takanobu Maezawa, Junpei Kawauchi, Hanae Nodono, Yukako Hirao, Osamu Nishimura, Haruka Nakagawa, Kiyono Sekii, Kenta Tasaka, Hiroshi Tarui, Kiyokazu Agata, Motonori Hoshi, Kazuya Kobayashi, Yasufumi Sakakibara and Midori Matsumoto
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Journal Title
Zoological Science 24
Pages: 31-37
NAID
Related Report
Peer Reviewed
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[Journal Article] The Dugesia ryukyuensis Database as a Molecular Resource for Studying on Switching of Reproductive System2007
Author(s)
Hideyuki Ishizuka, Takanobu Maezawa, Junpei Kawauchi, Hanae Nodono, Yukako Hirao, Osamu Nishimura, Haruka Nakagawa, Kiyono Sekii, Kenta Tasaka, Hiroshi Tarui, Kiyokazu Agata, Motonori Hoshi, Kazuya Kobayashi, Yasubumi Sakakibara, Midori Matsumoto
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Journal Title
Zool Sci. 24
Pages: 31-37
NAID
Related Report
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[Presentation] Comprehensive studies in planarians2004
Author(s)
Midori Matsumoto, Kazuya Kobayashi, Motonori Hoshi
Organizer
10th International Congress of Reproduction and Development Jun
Place of Presentation
Newcastle -upon-Tyne UK
Year and Date
2004-06-21
Related Report
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