| Budget Amount *help |
¥91,800,000 (Direct Cost: ¥91,800,000)
Fiscal Year 2009: ¥12,900,000 (Direct Cost: ¥12,900,000)
Fiscal Year 2008: ¥12,900,000 (Direct Cost: ¥12,900,000)
Fiscal Year 2007: ¥12,500,000 (Direct Cost: ¥12,500,000)
Fiscal Year 2006: ¥12,500,000 (Direct Cost: ¥12,500,000)
Fiscal Year 2005: ¥29,400,000 (Direct Cost: ¥29,400,000)
Fiscal Year 2004: ¥11,600,000 (Direct Cost: ¥11,600,000)
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| Research Abstract |
All the subunit proteins were localized in the baseplate before and after infection by a combination of X-ray crystallography and three-dimensional image econstruction from electron-micrographs. As a result, the gross structural change of the baseplate upon infection can be interpreted by the change of the relative positions of the subunits. Also, a new method was developed, which indicated that the stringent sequential assembly of the baseplate wedge is based on the induced-fit of the subunits upon binding.
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